|
![]() |
|
|
Zanamivir
drug data and news
Zanamivir drug data, resources, and news articles (when available). Onconews.org provides news on cancer research. This section, which includes profiles on medicines that may or not be cancer-related is in beta form. If things run smoothly we will be releasing a new format late in the summer of 2006.
|
| Generic name | Zanamivir | ||
| Brand Names/Synonyms | GANA; GG 167; GNA; MODIFIED SIALIC ACID; Relenza; See Remark 8; ZMR; Zanamavir; Zanamivir | ||
| Indication | For the prevention and treatment of influenza | ||
| Sponsored links | Description | Not Available | |
| Pharmacology | Zanamivir, an antiviral agent, is a neuraminidase inhibitor indicated for treatment of uncomplicated acute illness due to influenza A and B virus in adults and pediatric patients 7 years and older who have been symptomatic for no more than 2 days. | ||
| Mechanism Of Action | The proposed mechanism of action of zanamivir is via inhibition of influenza virus neuraminidase with the possibility of alteration of virus particle aggregation and release. | ||
| Zanamivir News (When available) |
'Flu and children 17 May 2006 Bird Flu May Infect People Through Digestive Tract (Update2) May 9, 2006 Experts weigh bird flu threat May 14, 2006 Conference of Federal-Provincial Territorial Ministers of Health ... May 13, 2006 Gen ID to develop new bird flu drugs May 9, 2006 AXE THREAT PLANT WINS 100 JOBS May 12, 2006 GSK board okays sale of animal health unit Apr 28, 2006 Cornell Bird Experts Monitor for Signs of Avian Flu (Update2) May 6, 2006 Live bird flu virus found in victim's blood May 4, 2006 GlaxoSmithKline Awarded $274 Million HHS Contract; Company to ... May 4, 2006 GSK initiates human trial programme with two H5N1 pandemic flu ... Apr 20, 2006 Full Text Apr 20, 2006 | ||
| Dosage Forms | POWDER | ||
| Drug_Category | Antivirals; Enzyme Inhibitors; Neuraminidase Inhibitors; ATC:J05AH01 | ||
| Absorption | 4% to 17% following an orally inhaled dose | ||
| Interactions |
-->Interactions for Zanamivir: No clinically significant pharmacokinetic drug interactions are predicted based on data from in vitro studies. | ||
| Toxicity | Not Available | ||
| Organisms Affected | Influenza A virus; Influenza B virus | ||
| Chemical IUPAC Name | 5-acetamido-4-guanidino-6-(1,2,3-trihydroxypropyl)-5,6-dihydro-4H-pyran-2-carboxylic acid | ||
| Chemical Formula | C12H20N4O7 | ||
| Molecular Weight | 332.31 g/mol | ||
| Smiles String | CC(=O)NC1C(C=C(OC1C(C(CO)O)O)C(=O)O)N=C(N)N | ||
| Melting Point | Not Available | ||
| Water Solubility | Not Available | ||
| State | Solid | ||
| LogP/Hphobicity | -3.67 | ||
| Isoelectric Point | Not Available | ||
| Biotransformation | Not metabolized | ||
| Half Life | 2.5-5.1 hours | ||
| Protein Binding [%] | <10% | ||
| RxList Link | RXlist | ||
| Sponsored links | |||
| Drug Reference |
http://www.drugs.com/cons/Zanamivir.html http://www.rxlist.com/cgi/generic2/zanam.htm | ||
| Drug Type | Approved Drug | ||
| Accession No | APRD00378 | ||
| CAS Registry Number | 139110-80-8 | ||
| KEGG Compound ID | C08095 | ||
| PubChem ID | SID:197092 | ||
| PharmGKB ID | PA451953 | ||
| SwissProt ID | Not Available | ||
| GenBank ID | Not Available | ||
| Drug ID Number [DIN] | 2240863 |
|
Home | About | Cancers | Treatment | Medications Copyright onconews.org 2005. All Rights Reserved. |