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Vitamin C
drug data and news
Vitamin C drug data, resources, and news articles (when available). Onconews.org provides news on cancer research. This section, which includes profiles on medicines that may or not be cancer-related is in beta form. If things run smoothly we will be releasing a new format late in the summer of 2006.
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| Generic name | Vitamin C | ||
| Brand Names/Synonyms | AA; Adenex; Allercorb; Antiscorbic Vitamin; Antiscorbutic Vitamin; Arco-Cee; Ascoltin; Ascor-B.I.D.; Ascorb; Ascorbajen; Ascorbate; Ascorbic Acid; Ascorbicab; Ascorbicap; Ascorbicin; Ascorbin; Ascorbutina; Ascorin; Ascorteal; Ascorvit; C-Level; C-Long; C-Quin; C-Span; C-Vimin; Cantan; Cantaxin; Catavin C; Ce Lent; Cebicure; Cebid; Cebion; Cebione; Cecon; Cee-Caps Td; Cee-Vite; Cegiolan; Ceglion; Celaskon; Celin; Cemagyl; Cemill; Cenetone; Cenolate; Cereon; Cergona; Cescorbat; Cetamid; Cetane; Cetane-Caps Tc; Cetane-Caps Td; Cetebe; Cetemican; Cevalin; Cevatine; Cevex; Cevi-Bid; Cevimin; Cevital; Cevitamic Acid; Cevitamin; Cevitan; Cevitex; Cewin; Ciamin; Cipca; Citriscorb; Colascor; Component of Chromagen; Component of Cortalex; Component of E and C-Level; Component of Endoglobin Forte; Component of Ferancee; Component of Freancee; Component of Stuartinic; Component of Tolfrinic; Component of Veliten; Concemin; Davitamon C; Duoscorb; Ferrous Ascorbate; Hicee; Hybrin; IDO-C; Iron-Ascorbic Acid Complexes; Kyselina Askorbova; L-Ascorbate; L-Ascorbic Acid; L-Ascorbic Acid Extra Pure; L-Lyxoascorbic Acid; L-Xyloascorbic Acid; Laroscorbine; Lemascorb; Liqui-Cee; Mediatric Component Of; Meri-C; NCI-C54808; NSC 33832; Natrascorb; Natrascorb Injectable; Planavit C; Proscorbin; Redoxon; Ribena; Roscorbic; Scorbacid; Scorbu-C; Secorbate; Sodascorbate; Testascorbic; Vicelat; Vicin; Vicomin C; Viforcit; Viscorin; Vitace; Vitacee; Vitacimin; Vitacin; Vitamin C; Vitamisin; Vitascorbol; Xitix; Xyloascorbic Acid, L- | ||
| Indication | Used to treat vitamin C deficiency, scurvy, delayed wound and bone healing, urine acidification, and in general as an antioxidant. It has also been suggested to be an effective antiviral agent. | ||
| Sponsored links | Description | Not Available | |
| Pharmacology | Ascorbic Acid (vitamin C) is a water-soluble vitamin indicated for the prevention and treatment of scurvy, as ascorbic acid deficiency results in scurvy. Collagenous structures are primarily affected, and lesions develop in bones and blood vessels. Administration of ascorbic acid completely reverses the symptoms of ascorbic acid deficiency. | ||
| Mechanism Of Action | In humans, an exogenous source of ascorbic acid is required for collagen formation and tissue repair by acting as a cofactor in the posttranslational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins. Ascorbic acid is reversibly oxidized to dehydroascorbic acid in the body. These two forms of the vitamin are believed to be important in oxidation-reduction reactions. The vitamin is involved in tyrosine metabolism, conversion of folic acid to folinic acid, carbohydrate metabolism, synthesis of lipids and proteins, iron metabolism, resistance to infections, and cellular respiration. | ||
| Vitamin C News (When available) |
Fight Premature Aging with Supplements 17 May 2006 DSM making long-term investment in China 17 May 2006 Short and sweet 17 May 2006 Can the right diet prevent breast cancer? 17 May 2006 Chill naturally 17 May 2006 “Power UP!� with ZESPRI Kiwifruit 17 May 2006 What food could ease my husband's depression? 17 May 2006 In some cases, vitamins do more harm than good 17 May 2006 Pack an anti-ageing lunchbox 17 May 2006 This versatile lawn weed is a dandy for salads, side dishes 17 May 2006 In Season: Dandelion greens 17 May 2006 Questions and Answers on Health and Nutrition Claims 17 May 2006 Janson Beckett Cosmeceuticals Launches Lip Plumper; Latest ... 17 May 2006 Spring Into Light & Healthy Meals 17 May 2006 Versatility and bite make arugula a greater green 17 May 2006 Cashews add distinction to two entrees 17 May 2006 Which of the Hundreds of Tomato Varieties Should I Plant? 17 May 2006 Beach Body Basics 17 May 2006 Dutch consortium could yield controlled release technology 17 May 2006 Clinical Study Shows Zila's Ester-C(R) Superior to Vitamin C ... May 4, 2006 Vitamin C, lysine still blight BASF margins May 4, 2006 Zila stakes out Ester-C advantage with enhanced product May 3, 2006 Ester-C gets tolerability boost May 5, 2006 Extra Vitamin C and E Don't Prevent Preeclampsia Apr 26, 2006 Study: Vitamin C and E don't reduce risk of pregnancy-related ... Apr 27, 2006 Vitamin C, E found ineffective to prevent late pregnancy ... Apr 27, 2006 Cigarette with added vitamin C Apr 27, 2006 Vitamin C, E Intake Does Not Reduce Pre-eclampsia Risk, Study Says Apr 27, 2006 Vitamin C and E Supplements Do Not Prevent Pre-Eclampsia Apr 27, 2006 Doctor cautious of vitamin C study Apr 28, 2006 Antioxidants Don't Decrease Preeclampsia -- Vitamin C and E ... Apr 27, 2006 Britain's daily dose of Vitamin C may be about to get a lot more ... May 15, 2006 New Warnings About Vitamins C & E May 1, 2006 Call for More Study on Vitamin C and Cancer Apr 24, 2006 Cold or flu? May 15, 2006 12-Hour Vitamin C Capsules: New Beadlets Maintain Optimal Levels ... Apr 17, 2006 Call for More Study on Vitamin C and Cancer Apr 24, 2006 Paper studies tartaric acid, vitamin C in grape Apr 19, 2006 Strawberries pack nutritional punch May 15, 2006 Beauty: wellness treatments May 15, 2006 | ||
| Dosage Forms | Capsules, tablets (chewable, immediate and extended release), lozenges, solution, and parenteral injection | ||
| Drug_Category | ATC:A11GA01; Antioxidants; Essential Vitamin; Free Radical Scavengers; Vitamins (Vitamin C) | ||
| Absorption | 70% to 90% | ||
| Interactions |
Drug Interactions for Vitamin C: Limited evidence suggests that ascorbic acid may influence the intensity and duration of action of bishydroxycoumarin. | ||
| Toxicity | Not Available | ||
| Organisms Affected | Humans and other mammals | ||
| Chemical IUPAC Name | 2-(1,2-dihydroxyethyl)-4,5-dihydroxy-furan-3-one | ||
| Chemical Formula | C6H8O6 | ||
| Molecular Weight | 176.124 g/mol | ||
| Smiles String | C(C(C1C(=O)C(=C(O1)O)O)O)O | ||
| Melting Point | 191 °C | ||
| Water Solubility | 4E+005 mg/L | ||
| State | Solid | ||
| LogP/Hphobicity | -1.305 | ||
| Isoelectric Point | 4.7 | ||
| Biotransformation | Hepatic. Ascorbic acid is reversibly oxidised (by removal of the hydrogen from the enediol group of ascorbic acid) to dehydroascorbic acid. The two forms found in body fluids are physiologically active. Some ascorbic acid is metabolised to inactive compounds including ascorbic acid-2-sulfate and oxalic acid. | ||
| Half Life | 16 days (3.4 hours in people who have excess levels of vitamin C) | ||
| Protein Binding [%] | 25% | ||
| RxList Link | RXlist | ||
| Sponsored links | |||
| Drug Reference |
http://www.drugs.com/cons/Vitamin_C.html http://www.rxlist.com/cgi/generic3/vitamc.htm http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/vit_0264.shtml | ||
| Drug Type | Approved Drug | ||
| Accession No | APRD00084 | ||
| CAS Registry Number | 50-81-7 | ||
| KEGG Compound ID | C00072 | ||
| PubChem ID | SID:313686 | ||
| PharmGKB ID | PA451898 | ||
| SwissProt ID | Not Available | ||
| GenBank ID | Not Available | ||
| Drug ID Number [DIN] | 583960 |
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