Vitamin C drug data and news

Vitamin C drug data, resources, and news articles (when available). Onconews.org provides news on cancer research. This section, which includes profiles on medicines that may or not be cancer-related is in beta form. If things run smoothly we will be releasing a new format late in the summer of 2006.

Generic name Vitamin C
Brand Names/Synonyms AA; Adenex; Allercorb; Antiscorbic Vitamin; Antiscorbutic Vitamin; Arco-Cee; Ascoltin; Ascor-B.I.D.; Ascorb; Ascorbajen; Ascorbate; Ascorbic Acid; Ascorbicab; Ascorbicap; Ascorbicin; Ascorbin; Ascorbutina; Ascorin; Ascorteal; Ascorvit; C-Level; C-Long; C-Quin; C-Span; C-Vimin; Cantan; Cantaxin; Catavin C; Ce Lent; Cebicure; Cebid; Cebion; Cebione; Cecon; Cee-Caps Td; Cee-Vite; Cegiolan; Ceglion; Celaskon; Celin; Cemagyl; Cemill; Cenetone; Cenolate; Cereon; Cergona; Cescorbat; Cetamid; Cetane; Cetane-Caps Tc; Cetane-Caps Td; Cetebe; Cetemican; Cevalin; Cevatine; Cevex; Cevi-Bid; Cevimin; Cevital; Cevitamic Acid; Cevitamin; Cevitan; Cevitex; Cewin; Ciamin; Cipca; Citriscorb; Colascor; Component of Chromagen; Component of Cortalex; Component of E and C-Level; Component of Endoglobin Forte; Component of Ferancee; Component of Freancee; Component of Stuartinic; Component of Tolfrinic; Component of Veliten; Concemin; Davitamon C; Duoscorb; Ferrous Ascorbate; Hicee; Hybrin; IDO-C; Iron-Ascorbic Acid Complexes; Kyselina Askorbova; L-Ascorbate; L-Ascorbic Acid; L-Ascorbic Acid Extra Pure; L-Lyxoascorbic Acid; L-Xyloascorbic Acid; Laroscorbine; Lemascorb; Liqui-Cee; Mediatric Component Of; Meri-C; NCI-C54808; NSC 33832; Natrascorb; Natrascorb Injectable; Planavit C; Proscorbin; Redoxon; Ribena; Roscorbic; Scorbacid; Scorbu-C; Secorbate; Sodascorbate; Testascorbic; Vicelat; Vicin; Vicomin C; Viforcit; Viscorin; Vitace; Vitacee; Vitacimin; Vitacin; Vitamin C; Vitamisin; Vitascorbol; Xitix; Xyloascorbic Acid, L-
Indication Used to treat vitamin C deficiency, scurvy, delayed wound and bone healing, urine acidification, and in general as an antioxidant. It has also been suggested to be an effective antiviral agent.
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Description Not Available
Pharmacology Ascorbic Acid (vitamin C) is a water-soluble vitamin indicated for the prevention and treatment of scurvy, as ascorbic acid deficiency results in scurvy. Collagenous structures are primarily affected, and lesions develop in bones and blood vessels. Administration of ascorbic acid completely reverses the symptoms of ascorbic acid deficiency.
Mechanism Of Action In humans, an exogenous source of ascorbic acid is required for collagen formation and tissue repair by acting as a cofactor in the posttranslational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins. Ascorbic acid is reversibly oxidized to dehydroascorbic acid in the body. These two forms of the vitamin are believed to be important in oxidation-reduction reactions. The vitamin is involved in tyrosine metabolism, conversion of folic acid to folinic acid, carbohydrate metabolism, synthesis of lipids and proteins, iron metabolism, resistance to infections, and cellular respiration.
Vitamin C News
(When available)

Fight Premature Aging with Supplements  17 May 2006
...and appearance. Yet almost a third of women don't get enough Vitamin C, and 9 out of 10 Americans fail to get enough Vitamin E. A ... - Fashion Monitor Toronto,

DSM making long-term investment in China  17 May 2006
When the multiple approvals come through – hopefully by the end of next year - the venture will allow DSM to sell vitamin C in China for the first time. ... - NutraIngredients.com,

Short and sweet  17 May 2006
To begin with, they are an excellent source of beta-carotene, vitamin C, iron, potassium and fiber. And, "they make great pies," says Ferriera. ... - Cherry Hill Courier Post,

Can the right diet prevent breast cancer?  17 May 2006
...risk of cancer. In fact, high doses of vitamin C (more than 1g a day) may damage genes in cells, which could promote cancer. It is ... - Daily Mail - UK,

Chill naturally  17 May 2006
These would include kokam sharbat and lime juice that are also a good source of vitamin C; panha, the raw mango drink, made with jaggery is a perfect ... - Expressindia.com,

“Power UP!â€? with ZESPRI Kiwifruit  17 May 2006
Pratt touts kiwifruit’s high nutrient density, and stores of vitamin C, fiber, potassium and vitamin E among the reasons it is essential to a healthy diet. ... - FreshPlaza,

What food could ease my husband's depression?  17 May 2006
...foods can, independent of medication, have a positive impact on mood by stimulating endorphin production — most notably foods rich in protein and vitamin C. ... - Times Online,

In some cases, vitamins do more harm than good  17 May 2006
And the most recent reversal in the news: Higher doses of vitamin C and E for pregnant women did not reduce the risk for pre-eclampsia, a dangerous late-term ... - The Grand Rapids Press,

Pack an anti-ageing lunchbox  17 May 2006
Dark leafy vegetables such as broccoli and spinach are a rich source of vitamin C and anti-cancer substances, and berries are great for building up collagen in ... - ic Harrow.co.uk,

This versatile lawn weed is a dandy for salads, side dishes  17 May 2006
Two to three cups of greens provides 8 milligrams of beta carotene, 35 milligrams of vitamin C, 187 milligram of calcium and 3 milligrams of iron. ... - Centre Daily Times,

In Season: Dandelion greens  17 May 2006
...lion's teeth. Dandelion leaves are high in vitamin C, vitamin A and iron and have been used as a tonic for centuries. The bright ... - Salt Lake Tribune,

Questions and Answers on Health and Nutrition Claims  17 May 2006
...of a food. Examples include “high in vitamin C�, “low fat�, “no added sugar“and “high fibre�. Health claims maintain ... - EUROPA (press release),

Janson Beckett Cosmeceuticals Launches Lip Plumper; Latest ...  17 May 2006
AlphaDerma CE, the Janson Beckett regimen includes certified organic cleansers and toners, an Argireline-based facial prep, a dual source Vitamin C facial serum ... - Business Wire (press release),

Spring Into Light & Healthy Meals  17 May 2006
...fat and cholesterol free. They also provide dietary fiber, vitamin C, B6, potassium and other key nutrients. So while you enjoy ... - NBC 17.com,

Versatility and bite make arugula a greater green  17 May 2006
It also contains more beta-carotene and vitamin C than watercress, romaine or chicory, and more calcium than either collards or kale, two greens renowned for ... - Newark Star Ledger,

Cashews add distinction to two entrees  17 May 2006
...marketed. The "nose" of the apple contains the nut and is rich in vitamin C, copper, magnesium and healthful monounsaturated fats. ... - Seattle Post Intelligencer

Which of the Hundreds of Tomato Varieties Should I Plant?  17 May 2006
There are even varieties that have a lower acid content for the folks who can't eat a high-acid tomato, and varieties that have more Vitamin C than oranges. ... - Novato Advance,

Beach Body Basics  17 May 2006
Powerful food fix: Choose 100 percent orange juice as a flavorful pick-me-up that provides essential nutrients including vitamin C, folate and potassium that ... - KCRA.com,

Dutch consortium could yield controlled release technology  17 May 2006
Glucosamine, chondriotin, vitamin C and soy isoflavones products are amongst those to have been launched using controlled delivery technology (CDT) developed ... - NutraIngredients.com,

Clinical Study Shows Zila's Ester-C(R) Superior to Vitamin C ...  May 4, 2006
...by Zila, Inc.'s (Nasdaq: ZILA), wholly-owned subsidiary, Zila Nutraceuticals, Inc., showed that the Ester formulation of vitamin C caused significantly fewer ... - Genetic Engineering News,

Vitamin C, lysine still blight BASF margins  May 4, 2006
...chemicals division is bolstered by higher sales volume of aroma chemicals and vitamins A and E for animal nutrition, but the pressure over vitamin C and lysine ... - FoodNavigator.com,

Zila stakes out Ester-C advantage with enhanced product  May 3, 2006
...of Ester-C said to offer improved antioxidant and anti-carcinogenic potential, which should allow it to maintain its advantage in the vitamin C market until ... - NutraIngredients-usa.com,

Ester-C gets tolerability boost  May 5, 2006
Ester-C is an advanced form of vitamin C. Amongst the benefits is a neutral pH, which, says Zila, means that the vitamin is gentler on the stomach than ... - NutraIngredients-usa.com,

Extra Vitamin C and E Don't Prevent Preeclampsia  Apr 26, 2006
..."Our study found that for women in the first pregnancy, taking vitamin C and E supplements did not reduce the risk of developing preeclampsia," said study ... - Forbes

Study: Vitamin C and E don't reduce risk of pregnancy-related ...  Apr 27, 2006
...(AP) - A disappointing new study found that vitamin C and E supplements given to healthy pregnant women do not reduce their risk of developing pre-eclampsia, a ... - Canada.com,

Vitamin C, E found ineffective to prevent late pregnancy ...  Apr 27, 2006
WASHINGTON, April 27 (Xinhua) -- Vitamin C and E supplements cannot help prevent the development of preeclampsia, a late pregnancy complication that can be ... - Xinhua,

Cigarette with added vitamin C  Apr 27, 2006
Everyone knows cigarettes can send you to an early grave - but at least new ones injected with vitamin C could help keep your teeth white. ... - Daily Mail - UK,

Vitamin C, E Intake Does Not Reduce Pre-eclampsia Risk, Study Says  Apr 27, 2006
Taking vitamin C and vitamin E supplements does not reduce a pregnant woman's risk of developing pre-eclampsia, according to a study published in the April 27 ... - Kaiser network.org,

Vitamin C and E Supplements Do Not Prevent Pre-Eclampsia  Apr 27, 2006
NORTH ADELAIDE, Australia, April 27 — Vitamin C and E supplements during pregnancy in normal-risk nulliparous women did not reduce their risk of pre-eclampsia ... - MedPage Today,

Doctor cautious of vitamin C study  Apr 28, 2006
...article I wrote an editorial on and some other ongoing preclinical and some clinical news, we decided to do a formal phase one trial of vitamin C in advanced ... - Parksville Qualicum News,

Antioxidants Don't Decrease Preeclampsia -- Vitamin C and E ...  Apr 27, 2006
...be harmful for the heart. And a June 2004 report that suggested a link between vitamin C and arthritis. If this study had found ... - American Council on Science and Health,

Britain's daily dose of Vitamin C may be about to get a lot more ...  May 15, 2006
...reached earlier in the week. Britain's daily dose of Vitamin C may be about to get a lot more expensive. The price of frozen orange ... - FreshPlaza,

New Warnings About Vitamins C & E  May 1, 2006
Perhaps the most surprising scientific failures have occurred with the darlings of the antioxidants world - Vitamin E and Vitamin C. ... - abc7news.com,

Call for More Study on Vitamin C and Cancer  Apr 24, 2006
...cancer, confirmed by histopathologic review, where patients had unexpectedly long survival times after receiving high-dose intravenous vitamin C therapy. ... - Yahoo! News (press release)

Cold or flu?  May 15, 2006
Increase your intake of vitamin A to 10 000 IUs a day and vitamin C to 1000-2000mg a day. Vitamin C may reduce the severity and duration of symptoms. ... - Health24.com,

12-Hour Vitamin C Capsules: New Beadlets Maintain Optimal Levels ...  Apr 17, 2006
Dietary supplement breakthrough -- new technology now makes it possible to slowly release vitamin C over a 12-hour period to help maintain optimal vitamin C ... - PR Web (press release),

Call for More Study on Vitamin C and Cancer  Apr 24, 2006
Case Study Review by NIH Warrants Additional Research for High Dose IV Vitamin C and the Hydrogen Peroxide Effect on Cancer Tumors WICHITA, Kan., April 24 ... - PR Newswire (press release),

Paper studies tartaric acid, vitamin C in grape  Apr 19, 2006
Vitamin C and L-tartaric acid are plant-derived metabolites which are of value to viticulture and human health. Grapes, in particular ... - Checkbiotech.org (press release),

Strawberries pack nutritional punch  May 15, 2006
Packed with nutrients, a one cup serving contains only 43 calories and 136 percent of the recommended daily allowance of vitamin C. ... - Clarksville Leaf Chronicle,

Beauty: wellness treatments  May 15, 2006
Origins' scientists found that rhodolia has impressive firming qualities when applied topically, and when mixed with antioxidant vitamin C (which helps to ... - Telegraph.co.uk,

Dosage Forms Capsules, tablets (chewable, immediate and extended release), lozenges, solution, and parenteral injection
Drug_Category ATC:A11GA01; Antioxidants; Essential Vitamin; Free Radical Scavengers; Vitamins (Vitamin C)
Absorption 70% to 90%
Interactions Drug Interactions for Vitamin C:

Limited evidence suggests that ascorbic acid may influence the intensity and duration of action of bishydroxycoumarin.

Toxicity Not Available
Organisms Affected Humans and other mammals
Chemical IUPAC Name 2-(1,2-dihydroxyethyl)-4,5-dihydroxy-furan-3-one
Chemical Formula C6H8O6
Molecular Weight 176.124 g/mol
Smiles String C(C(C1C(=O)C(=C(O1)O)O)O)O
Melting Point 191 °C
Water Solubility 4E+005 mg/L
State Solid
LogP/Hphobicity -1.305
Isoelectric Point 4.7
Biotransformation Hepatic. Ascorbic acid is reversibly oxidised (by removal of the hydrogen from the enediol group of ascorbic acid) to dehydroascorbic acid. The two forms found in body fluids are physiologically active. Some ascorbic acid is metabolised to inactive compounds including ascorbic acid-2-sulfate and oxalic acid.
Half Life 16 days (3.4 hours in people who have excess levels of vitamin C)
Protein Binding [%] 25%
RxList Link RXlist
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Drug Reference http://www.drugs.com/cons/Vitamin_C.html
http://www.rxlist.com/cgi/generic3/vitamc.htm
http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/vit_0264.shtml
Drug Type Approved Drug
Accession No APRD00084
CAS Registry Number 50-81-7
KEGG Compound ID C00072
PubChem ID SID:313686
PharmGKB ID PA451898
SwissProt ID Not Available
GenBank ID Not Available
Drug ID Number [DIN] 583960

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