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Tranylcypromine
drug data and news
Tranylcypromine drug data, resources, and news articles (when available). Onconews.org provides news on cancer research. This section, which includes profiles on medicines that may or not be cancer-related is in beta form. If things run smoothly we will be releasing a new format late in the summer of 2006.
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| Generic name | Tranylcypromine | ||
| Brand Names/Synonyms | Dl-Tranylcypromine; Parnate; SKF 385; Transamine; Tranylcypromine | ||
| Indication | Depression | ||
| Sponsored links | Description | Not Available | |
| Pharmacology | Tranylcypromine belongs to a class of antidepressants called monoamine oxidase inhibitors (MAOIs). Tranylcypromine works by irreversibly blocking the action of a chemical substance known as monoamine oxidase (MAO) in the nervous system. Within neurons, MAO appears to regulate the levels of monoamines released upon synaptic firing. Since depression is associated with low levels of monoamines, the inhibition of MAO serves to ease depressive symptoms. | ||
| Mechanism Of Action | The irreversible inhibition of MAO by Tranylcypromine causes an increase in the levels of serotonin, norepinephrine, and dopamine in the neuron, relieving depressive symptoms. | ||
| Tranylcypromine News (When available) |
The Can-SAD Study: A Randomized Controlled Trial of the ... May 2, 2006 | ||
| Dosage Forms | TABLET | ||
| Drug_Category | Anti-anxiety Agents; Antidepressants; Antidepressants; ATC:N06AF04 | ||
| Absorption | Not Available | ||
| Interactions |
Interactions for Tranylcypromine: No Information Provided. | ||
| Toxicity | Not Available | ||
| Organisms Affected | Humans and other mammals | ||
| Chemical IUPAC Name | 2-phenylcyclopropan-1-amine | ||
| Chemical Formula | C9H11N | ||
| Molecular Weight | 133.19 g/mol | ||
| Smiles String | C1C(C1N)C2=CC=CC=C2 | ||
| Melting Point | Not Available | ||
| Water Solubility | Not Available | ||
| State | Solid | ||
| LogP/Hphobicity | 1.434 | ||
| Isoelectric Point | Not Available | ||
| Biotransformation | Not Available | ||
| Half Life | Not Available | ||
| Protein Binding [%] | Not Available | ||
| RxList Link | RXlist | ||
| Sponsored links | |||
| Drug Reference |
http://www.drugs.com/cons/Tranylcypromine.html http://www.rxlist.com/cgi/generic2/tranylcypromine.htm | ||
| Drug Type | Approved Drug | ||
| Accession No | APRD00645 | ||
| CAS Registry Number | 155-09-9 | ||
| KEGG Compound ID | C07155 | ||
| PubChem ID | SID:9364 | ||
| PharmGKB ID | PA451741 | ||
| SwissProt ID | Not Available | ||
| GenBank ID | Not Available | ||
| Drug ID Number [DIN] | 1919598 |
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