Timolol drug data and news

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Study Demonstrates Benefits of Combination Treatment for Glaucoma  May 11, 2006
...achieved clinically significant additional reduction in intraocular pressure (IOP) when treated with Cosopt® (dorzolamide hydrochloride/timolol maleate) alone ... - DG News

NEW STUDY DEMONSTRATES A SINGLE COMPOUND AS EFFECTIVE AS A FIXED ...  May 3, 2006
...bimatoprost) is as effective alone at lowering intraocular pressure (IOP) as a fixed combination (XALACOM) of latanoprost (Xalatan) combined with timolol. ... - ITNews,

Allergan Reports First Quarter Operating Results; Pharmaceutical ...  May 3, 2006
...for Medicinal Products for Human Use (CHMP) recommended that the European Commission approve GANFORT(R), Allergan's LUMIGAN(R)/timolol combination product ... - Genetic Engineering News,

Allergan Posts Q1 Loss, Forecasts Q2 Results Below Wall Street ...  May 3, 2006
...the Committee for Medicinal Products for Human Use recommended that the European Commission approve GANFORT, Allergan's LUMIGAN/timolol combination product for ... - Trading Markets,

(BW) Alcon's First Quarter Sales Rise 8.1 Percent, Net Earnings ...  Apr 24, 2006
DuoTrav(TM), a fixed combination of travoprost 0.004% and timolol 0.5%, received a positive recommendation for approval in the European Union by the ... - Houston Chronicle,

Alcon Q1 Net Earnings Rise 18.5% Primarily On Healthy Sales Growth ...  Apr 24, 2006
DuoTrav, a fixed combination of travoprost 0.004% and timolol 0.5%, received a positive recommendation for approval in the European Union by the Committee for ... - Trading Markets,

Glaucoma treatment has options  Apr 23, 2006
For example, beta blockers such as levobunolol (Betagan) or timolol (Betimol, Timoptic) can reduce the production of aqueous humor, and prostaglandin analogues ... - Fort Wayne Journal Gazette,

Beta-adrenergic blocking agents: Patients who are receiving a beta-adrenergic blocking agent orally and Timolol GFS should be observed for potential additive effects of beta-blockade, both systemic and on intraocular pressure. Patients should not usually receive two topical ophthalmic beta-adrenergic blocking agents concurrently.

Calcium antagonists: Caution should be used in the co-administration of beta-adrenergic blocking agents, such as Timolol GFS, and oral or intravenous calcium antagonists because of possible atrioventricular conduction disturbances, left ventricular failure, or hypotension. In patients with impaired cardiac function, co-administration should be avoided.

ENDOCRINE

Masked symptoms of hypoglycemia in diabetic patients. SPECIAL SENSES

Signs and symptoms of ocular irritation including blepharitis, keratitis, and dry eyes; ptosis; decreased corneal sensitivity; cystoid macular edema; visual disturbances including refractive changes and diplopia; pseudopemphigoid; tinnitus and choroidal detachment following filtration surgery.

UROGENITAL

Retroperitoneal fibrosis, decreased libido, impotence and Peyronieís disease.

The following additional adverse effects have been reported in clinical experience with ORAL timolol maleate or other ORAL beta-blocking agents and may be considered potential effects of ophthalmic timolol maleate: Allergic: Erythematous rash, fever combined with aching and sore throat, laryngospasm with respiratory distress; Body as a Whole: Extremity pain, decreased exercise tolerance, weight loss; Cardiovascular: Worsening of arterial insufficiency, vasodilatation; Digestive: Gastrointestinal pain, hepatomegaly, vomiting, mesenteric arterial thrombosis, ischemic colitis; Hematologic: Nonthrombocytopenic purpura, thrombocytopenic purpura, agranulocytosis; Endocrine: Hyperglycemia, hypoglycemia; Skin: Pruritus, skin irritation, increased pigmentation, sweating; Musculoskeletal: Arthralgia; Nervous System/Psychiatric: Vertigo, local weakness, diminished concentration, reversible mental depression progressing to catatonia, an acute reversible syndrome characterized by disorientation for time and place, emotional lability, slightly clouded sensorium, and decreased performance on neuropsychometric tests; Respiratory: Rales, bronchial obstruction; Urogenital: Urination difficulties.