Testolactone drug data and news

Testolactone drug data, resources, and news articles (when available). Onconews.org provides news on cancer research. This section, which includes profiles on medicines that may or not be cancer-related is in beta form. If things run smoothly we will be releasing a new format late in the summer of 2006.

Generic name Testolactone
Brand Names/Synonyms Dea No. 4000; Fludestrin; HSDB 3255; SQ 9538; Teolit; Teslac; Teslak; Testolacton; Testolactona [Inn-Spanish]; Testolactone; Testolactone [Usan:Inn]; Testolactonum [Inn-Latin]; Testolattone [Dcit]
Indication Palliative treatment of advanced breast cancer in postmenopausal women
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Description Not Available
Pharmacology Not Available
Mechanism Of Action Not Available
Testolactone News
(When available)
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Dosage Forms Not Available
Drug_Category Antineoplastic Agents;
Absorption Not Available
Interactions Interactions for Testolactone:

When administered concurrently, testolactone may increase the effects of oral anticoagulants; monitor and adjust anticoagulant dosage accordingly.

Drug/Laboratory Test Interactions:   Physiologic effects of testolactone may result in decreased estradiol concentrations with radioimmunoassays for estradiol, increased plasma calcium concentrations, and increased 24-hour urinary excretion of creatine and 17-ketosteroids.

Toxicity Not Available
Organisms Affected Humans and other mammals
Chemical IUPAC Name Not Available
Chemical Formula C19H24O3
Molecular Weight 300.392 g/mol
Smiles String CC12CCC3C(C1CCC(=O)O2)CCC4=CC(=O)C=CC34C
Melting Point Not Available
Water Solubility Not Available
State Solid
LogP/Hphobicity 3.663
Isoelectric Point Not Available
Biotransformation Not Available
Half Life Not Available
Protein Binding [%] ~85%
RxList Link RXlist
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Drug Reference http://www.drugs.com/cons/Testolactone.html
http://www.rxlist.com/cgi/generic2/testolactone.htm
Drug Type Approved Drug
Accession No APRD00640
CAS Registry Number 968-93-4
KEGG Compound ID C02197
PubChem ID SID:157104
PharmGKB ID PA451626
SwissProt ID Not Available
GenBank ID Not Available
Drug ID Number [DIN] Not Available

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