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Tenoxicam
drug data and news
Tenoxicam drug data, resources, and news articles (when available). Onconews.org provides news on cancer research. This section, which includes profiles on medicines that may or not be cancer-related is in beta form. If things run smoothly we will be releasing a new format late in the summer of 2006.
| Generic name |
Tenoxicam
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| Brand Names/Synonyms |
Apo-Tenoxicam; Novo-Tenoxicam; Tenoxicam; Tenoxicam [Usan:Ban:Inn:Jan]; Tenoxicamum [Inn-Latin]; Tilcotil |
| Indication |
Tenoxicam is indicated in the treatment of rheumatoid arthritis, osteoarthritis, backache, and pain. |
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Description |
Not Available |
| Pharmacology |
Tenoxicam, an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain. |
| Mechanism Of Action |
The antiinflammatory effects of Tenoxicam |
Tenoxicam News
(When available) |
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| Dosage Forms |
Tablet, Suppository, Injection |
| Drug_Category |
Anti-inflammatory Agents; ATC:M01AC02 |
| Absorption |
Oral absorption of tenoxicam is rapid and complete (absolute bioavailability 100%). |
| Interactions |
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| Toxicity |
Not Available |
| Organisms Affected |
Humans and other mammals |
| Chemical IUPAC Name |
4-(hydroxy-pyridin-2-ylamino-methylidene)-3-methyl-2,2-dioxo-2u{6},7-dithia-3-azabicyclo[4.3.0]nona-8,10-dien-5-one |
| Chemical Formula |
C13H11N3O4S2 |
| Molecular Weight |
337.376 g/mol |
| Smiles String |
CN1C(=C(NC2=CC=CC=N2)O)C(=O)C3=C(S1(=O)=O)C=CS3 |
| Melting Point |
211 °C |
| Water Solubility |
45 mg/L |
| State |
Solid |
| LogP/Hphobicity |
2.4 |
| Isoelectric Point |
Not Available |
| Biotransformation |
Tenoxicam is metabolized in the liver to several pharmacologically inactive metabolites (mainly 5'-hydroxy-tenoxicam). |
| Half Life |
72 hours (range 59 to 74 hours) |
| Protein Binding [%] |
99% |
| RxList Link |
Not Available>RXlist |
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| Drug Reference |
http://www.drugs.com/cons/Tenoxicam.html |
| Drug Type |
Approved Drug |
| Accession No |
APRD00011 |
| CAS Registry Number |
59804-37-4 |
| KEGG Compound ID |
C13234 |
| PubChem ID |
SID:183540 |
| PharmGKB ID |
PA131890625 |
| SwissProt ID |
Not Available |
| GenBank ID |
Not Available |
| Drug ID Number [DIN] |
2231120
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