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Serum albumin iodonated
drug data and news
Serum albumin iodonated drug data, resources, and news articles (when available). Onconews.org provides news on cancer research. This section, which includes profiles on medicines that may or not be cancer-related is in beta form. If things run smoothly we will be releasing a new format late in the summer of 2006.
| Generic name |
Serum albumin iodonated
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| Brand Names/Synonyms |
Serum albumin precursor; Megatope (IsoTex Diagnostics) |
| Indication |
For determination of total blood and plasma volumes |
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Description |
A diagnostic radiopharmaceutical containing iodinated I 131 albumin for intravenous imaging. Following intravenous injection, radioiodinated albumin human is uniformly distributed throughout the intravascular pool within 10 minutes; extravascular distribution takes place more slowly (2 days). Megatope is indicated for use in determinations of total blood and plasma volumes, cardiac output, cardiac and pulmonary blood volumes and circulation times |
| Pharmacology |
Regulates the colloidal osmotic pressure of blood. It is used to increase the circulating plasma volume, thereby reducing hemoconcentrtion and blood viscosity. Also used as a transport protein that binds naturally occurring, therapeutic and toxic materials in circulation. |
| Mechanism Of Action |
Serum albumin acts as a high molecular weight, very soluble osmolyte |
Serum albumin iodonated News
(When available) |
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| Dosage Forms |
Not Available |
| Drug_Category |
Imaging Agents |
| Absorption |
Not Available |
| Interactions |
Not Available |
| Toxicity |
Not Available |
| Organisms Affected |
Humans and other mammals |
| Chemical IUPAC Name |
Human serum albumin |
| Chemical Formula |
C2936H4624N786O889S41 |
| Molecular Weight |
66472.2 |
| Smiles String |
Not Available |
| Melting Point |
62 oC (Flora, K. et al., Biophys J. 75:1084-1096 (1998)) |
| Water Solubility |
Not Available |
| State |
Transparent, slightly viscous, aqueous liquid |
| LogP/Hphobicity |
-0.395 |
| Isoelectric Point |
5.67 |
| Biotransformation |
Not Available |
| Half Life |
Not Available |
| Protein Binding [%] |
Not Available |
| RxList Link |
Not Available>RXlist |
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| Drug Reference |
Not Available |
| Drug Type |
Approved Drug |
| Accession No |
BIOD00089 |
| CAS Registry Number |
9048-49-1 |
| KEGG Compound ID |
Not Available |
| PubChem ID |
Not Available |
| PharmGKB ID |
Not Available |
| SwissProt ID |
ALBU_HUMAN (P02768) |
| GenBank ID |
M12523 |
| Drug ID Number [DIN] |
Not Available
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