|
Secretin,synthetic
drug data and news
Secretin,synthetic drug data, resources, and news articles (when available). Onconews.org provides news on cancer research. This section, which includes profiles on medicines that may or not be cancer-related is in beta form. If things run smoothly we will be releasing a new format late in the summer of 2006.
| Generic name |
Secretin,synthetic
|
| Brand Names/Synonyms |
Secremax, SecreFlo; Secremax, SecreFlo (Repligen Corp) |
| Indication |
For diagnosis of pancreatic exocrine dysfunction and gastrinoma |
|
Sponsored links
|
|
Description |
Not Available |
| Pharmacology |
Used in the diagnosis of pancreatic dysfunction or gastrinoma (stomach cancer), secretin is a hormone produced in the S cells of the duodenum in response to low local pH. It stimulates the secretion of bicarbonate from bicarbonate producing organs(liver, pancreas, Brunner's glands) when the pH drops below a set value. This helps neutralize the gastric acid entering the duodenum from the stomach. It also inhibits acid secretion from the stomach by reducing gastrin release from the G cells of the stomach. |
| Mechanism Of Action |
Secretin binds to the secretin receptor found on the lining of S cells in the duodenum and G cells in the stomach. Binding leads to the secrection of bicarbonate or the reduction of the secretion of gastrin. Properly functioning organs (duodenum, pancreas and stomach) should be responsive to this hormone |
Secretin,synthetic News
(When available) |
[an error occurred while processing this directive] |
| Dosage Forms |
POWDER FOR SOLUTION |
| Drug_Category |
Diagnostic Agents; pancreatic function (36:61.00) |
| Absorption |
Not Available |
| Interactions |
Not Available |
| Toxicity |
Not Available |
| Organisms Affected |
Humans and other mammals |
| Chemical IUPAC Name |
Not Available |
| Chemical Formula |
C130H219N43O42 |
| Molecular Weight |
3056.4 |
| Smiles String |
Not Available |
| Melting Point |
Not Available |
| Water Solubility |
Not Available |
| State |
Not Available |
| LogP/Hphobicity |
-0.463 |
| Isoelectric Point |
9.45 |
| Biotransformation |
Not Available |
| Half Life |
Not Available |
| Protein Binding [%] |
Not Available |
| RxList Link |
RXlist |
|
Sponsored links
|
|
| Drug Reference |
http://www.rxlist.com/cgi/generic3/secretin.htm |
| Drug Type |
Approved Drug |
| Accession No |
BIOD00039 |
| CAS Registry Number |
Not Available |
| KEGG Compound ID |
Not Available |
| PubChem ID |
Not Available |
| PharmGKB ID |
PA451315 |
| SwissProt ID |
Not Available |
| GenBank ID |
Not Available |
| Drug ID Number [DIN] |
874000
|
|
|
