Pseudoephedrine drug data and news

Pseudoephedrine drug data, resources, and news articles (when available). Onconews.org provides news on cancer research. This section, which includes profiles on medicines that may or not be cancer-related is in beta form. If things run smoothly we will be releasing a new format late in the summer of 2006.

Generic name Pseudoephedrine
Brand Names/Synonyms &Laquo;Psi&Raquo;-Ephedrin; &Laquo;Psi&Raquo;-Ephedrine; Afrinol; Balminil Decongestant Syrup; Benylin Decongestant; Besan; Cenafed; D-Isoephedrine; D-Pseudoephedrine; Decofed; Dimetapp Decongestant; Dimetapp Decongestant Pediatric Drops; Drixoral N.D.; Drixoral Nasal Decongestant; Efidac 24 Pseudoephedrine Hcl; Efidac/24; Eltor 120; Genaphed; HSDB 3177; Isoephedrine; Maxenal; Myfedrine; Novafed; PSEUDOEPHEDRINE; Pedia Care; Pseudo; Pseudo 60's; Pseudo-12; Pseudoefedrina [Inn-Spanish]; Pseudoephedrine; Pseudoephedrine D-Form; Pseudoephedrine Ephedrine; Pseudoephedrine Hcl; Pseudoephedrinum [Inn-Latin]; Psi-Ephedrin; Psi-Ephedrine; Robidrine; Sudafed; Sudafed 12 Hour; Sudafed Decongestant; Sudafed Decongestant 12 Hour; Sudafed Decongestant Extra Strength; Trans-Ephedrine; Triaminic; Triaminic Am Decongestant Formula; Triaminic Infant Oral Decongestant Drops
Indication Allergic rhinitis
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Description Not Available
Pharmacology Pseudoephedrine is a sympathomimetic agent, structurally similar to ephedrine, used to relieve nasal and sinus congestion and reduce air-travel-related otalgia in adults.
Mechanism Of Action Pseudoephedrine acts directly on both alpha- and, to a lesser degree, beta-adrenergic receptors. Through direct action on alpha-adrenergic receptors in the mucosa of the respiratory tract, pseudoephedrine produces vasoconstriction. Pseudoephedrine relaxes bronchial smooth muscle by stimulating beta2-adrenergic receptors. Like ephedrine, pseudoephedrine releasing norepinephrine from its storage sites, an indirect effect.
Pseudoephedrine News
(When available)

Expired Drugs Found At Discount Stores  16 May 2006
The station was able to buy pseudoephedrine there with no limitation and without signing a log or showing identification -- a violation of Indiana state law. ... - Channel Cincinnati.com,

Violence rises due to drug controls  16 May 2006
UNTIL restrictions on the sale of pseudoephedrine took effect in January, up to 50 per cent of the drug sold or stolen from pharmacies went into the illicit ... - Sydney Morning Herald,

New law helps fight meth epidemic  16 May 2006
Starting Wednesday, you’ll be inconvenienced in a minor way if you want to buy cold medicines that contain pseudoephedrine. You ... - Canton Repository (subscription),

Nevada braces for out-of-control meth use  16 May 2006
Act signed by President Bush in March, restricts and records the sale of the main ingredients needed to manufacture the drug: pseudoephedrine, ephedrine or ... - Las Vegas Business Press,

DEA training officers to raid meth labs  16 May 2006
..."The production of methamphetamine is unbelievably dangerous," Donnelly said. Meth starts off with a handful of pseudoephedrine. ... - San Antonio Express (subscription),

Drug users discover new ways to find meth  16 May 2006
The recent law banning over the counter sales of pseudoephedrine in Tennessee could eventually make meth lab busts a thing of the past. ... - WMC-TV,

Law enforcement officers learn how to combat 'Mexican meth'  16 May 2006
The big reason meth is now coming from M exico is that pseudoephedrine, a key ingredient in meth recipes, is being sold behind the counter. ... - KTVO,

Men Arrested for Making Meth  16 May 2006
...medicines behind the counter. Those cold medicines contain pseudoephedrine, a main ingredient in meth. Pharmacies are also required ... - Eyewitness News Memphis,

Data shows no need for special meth treatment  16 May 2006
She also did not disagree with the efforts of anti-meth task forces and stores keeping medicines with pseudoephedrine, such as Sudafed, behind the counter ... - The Casper Star Tribune,

Here are some stories we’re working on for Wednesday’s ...  16 May 2006
...years. Beginning today, over-the-counter cold medicines that have pseudoephedrine and ephedrine in them will move behind the counter. ... - Canton Repository (subscription),

4 challenging Lonoke County sheriff for job  16 May 2006
...“Meth labs are down,� he said, crediting a new state law that restricts the sale of pseudoephedrine, an ingredient for manufacturing methamphetamine. ... - Arkansas Democrat-Gazette (subscription),

BAIL AMOUNTS FOR SIX METH LAB DEFENDANTS LOWERED  May 15, 2006
...at about 6 am May 5 after the Soledad Police Department caught wind of a man who was reportedly attempting to buy large amounts of pseudoephedrine pills from a ... - CBS 5,

Pseudoephedrine getting harder to find  May 9, 2006
WASHINGTON, May 9 (UPI) -- Many US drugmakers have removed or will remove pseudoephedrine from over-the-counter decongestants to comply with a new federal law ... - DailyIndia.com,

Law restricts access to pseudoephedrine to curb `meth' abuse  Apr 28, 2006
The Combat Methamphetamine Act requires cold medicines with pseudoephedrine to be placed behind the counter and sets limits on individuals' daily and monthly ... - AAP News (subscription)

New Democrat Crystal Meth Bill aimed to pick up the ball the ...  May 15, 2006
Methamphetamine, something that the Campbell Liberal government should have done and didn't. The Bill will restrict the sale of pseudoephedrine and ephedrine ... - North Thompson Times,

Federal, state laws prompt decongestant reformulation  May 8, 2006
While at least 37 states have laws on the books that place restrictions on how much and where medicines containing the ingredient pseudoephedrine are sold, as ... - MarketWatch

War On Meth: The Counterattack  May 12, 2006
Virginia was the first jurisdiction in our area to impose restrictions on the sales of pseudoephedrine products, and by September, new federal legislation will ... - NBC 4.com,

Franklin County Man SentencedTo 10 Years in Meth Conspiracy  May 12, 2006
Preston Gillam, 30, of the Sullivan area, was indicted by a federal grand jury last November on charges of conspiracy to possess pseudoephedrine and possession ... - Missourian Publishing,

Watsonville men linked to major meth bust  May 9, 2006
About 2,000 packaged and loose Sudafed pills, or pseudoephedrine, a main ingredient in the manufacturing or "cooking" of methamphetamine were found at the home ... - Santa Cruz Sentinel,

Meth Crackdown Could Compromise Medical Privacy  May 9, 2006
...cleaned out house after house with an illegal, dangerous meth lab inside -- the epidemic fueled by cold medicines containing pseudoephedrine, the chemical meth ... - KIROtv.com,

Consumer Alert: Popular Nonprescription Medications Move Behind ...  May 11, 2006
With allergy season approaching its height, consumers are learning that popular nonprescription remedies containing pseudoephedrine have been moved behind ... - Yahoo! News (press release)

East Palo Alto meth lab raided  May 7, 2006
...premises, officers discovered four pounds of manufactured methamphetamine, one pound of heroin, one pound of cocaine and almost 67,000 pseudoephedrine pills in ... - San Mateo County Times,

Clamp on cold pills  May 2, 2006
MORE than 2700 "suspect buyers" of cold and flu tablets have been refused the pseudoephedrine-based medication in Queensland in the past six months. ... - Courier Mail,

Details Revealed In Major East Palo Alto Meth Bust  May 8, 2006
EAST PALO ALTO -- Four picnic tables covered with various pieces of surveillance equipment, drug paraphernalia, over a dozen bags of pseudoephedrine pills and ... - FoxReno.com,

COLLABORATION KEY IN EAST PALO ALTO METH LAB BUST  May 8, 2006
Four picnic tables covered with various pieces of surveillance equipment, drug paraphernalia, over a dozen bags of pseudoephedrine pills and firearms were put ... - CBS 5,

New limits on cold pills vex buyers  Apr 30, 2006
...gun on implementing some of the new federal restrictions on the sale of allergy and cold medications such as Sudafed and Claritin-D that contain pseudoephedrine ... - The Journal News.com,

Hospital setup found during meth lab bust  May 9, 2006
The common cold medicine contains pseudoephedrine, a key ingredient used to make methamphetamines. During the raid, authorities ... - San Francisco Chronicle,

Crude operating room found inside East Palo Alto meth lab  May 10, 2006
Ruezga, were arrested Friday after police found $250,000 worth of methamphetamine, cocaine and various weapons, and seized 70,000 pseudoephedrine pills, which ... - San Jose Mercury News,

Meth lab in home yields 'hospital room'  May 9, 2006
The common cold medicine contains pseudoephedrine, a key ingredient used to make methamphetamines. Authorities confiscated five ... - San Francisco Chronicle,

5 years for Burr Ridge mom who had meth lab on property  May 12, 2006
37, also pleaded guilty to misdemeanor retail theft on charges of shoplifting over-the-counter cold medications containing pseudoephedrine -- an ingredient ... - Chicago Sun-Times,

PEOPLE'S PHARMACY Generic-drug juggernaut rolls on  May 14, 2006
I used to use an oral decongestant like pseudoephedrine to keep my ears open, but it has not been working as well as it used to. ... - Houston Chronicle,

Police uncover large meth lab  May 9, 2006
Six men were arrested and 5 pounds of methamphetamine, 1 pound of cocaine, 1 pound of heroin and thousands of pseudoephedrine pills were seized. ... - San Mateo County Times,

NEW: 25,000 in medical equipment found at site of drug bust  May 11, 2006
Police there had received a call from a woman at a pharmacy who became suspicious after a man placed an order for 3,000 pseudoephedrine tablets. ... - San Mateo County Times,

Police, fire and courts  May 10, 2006
...of 673 Pennsylvania was arrested Monday and charged Tuesday with unlawful possession of a methamphetamine precursor - between 15 and 30 grams of pseudoephedrine ... - Peoria Journal Star,

Meth bill ‘small step’  May 12, 2006
Some of the medicines contain drugs (ephedrine and pseudoephedrine) that can be extracted and made into crystal methamphetamine (meth), an extremely addictive ... - The Leader,

Comprehensive meth plan urged  May 14, 2006
It concludes that tighter controls on the sale of key meth ingredient pseudoephedrine should reduce the supply of the drug in the state. - Lincoln Journal Star,

We are proud to serve our readers  May 14, 2006
Some shoplifting of pseudoephedrine from drugstores, a few thefts of anhydrous ammonia from local farms, a few meth labs, often in remote wooded areas. ... - Kalamazoo Gazette,

Probable Cause #6: Experience Can Kill You  May 14, 2006
Furthermore, the toxicology screening on the pilot revealed the presence of pseudoephedrine, phenylpropanolamine and ephedrine. ... - AVweb,

Bill aims to restrict crystal meth production  May 11, 2006
...meth. The bill would restrict the sale of pseudoephedrine products, which make up the drug, to behind the counter of a pharmacy. ... - Globe and Mail,

"All it took was one line:" former meth addict  May 10, 2006
Lisa Madigan fought long and hard to get a bill passed, restricting the sale of pseudoephedrine in Illinois, which has been a tremendous help. ... - Hancock County Journal Pilot,

Cure for common cold locked up  May 5, 2006
As of April 8, the federal law limits the sale of over-the-counter cough and sinus products such as Sudafed and Claritin D with pseudoephedrine, ephedrine or ... - Newsday,

Man gets 10 years for stealing cold medicine  May 2, 2006
A Kansan who ran out of a Wal-Mart with his arms full of pseudoephedrine was sentenced Monday in Wichita to 10 years in federal prison. ... - Kansas.com,

Police set sights on buyers of meth precursors  Apr 25, 2006
PRINCETON-The illegal purchase of cold medicines containing pseudoephedrine led to the weekend arrest of five suspects in Gibson County and Princeton Police ... - Princeton Daily Clarion,

Meth bust prompts news conference  May 8, 2006
...home at about 6 am Friday after the Soledad Police Department caught wind of a man who was reportedly buying large amounts of pseudoephedrine pills from a ... - Palo Alto Online,

Methamphetamine Bill  May 9, 2006
The act requires that nonprescription products containing pseudoephedrine (found in common cold medications and used in the illicit manufacturing of ... - Journal of American Medical Association (subscription),

In God we trust? How about each other?  May 14, 2006
She explained that any medicine containing pseudoephedrine, such as Sudafed or NyQuil or certain asthma medications, can be chemically extracted and used to ... - Augusta Free Press,

Six arrested during East Palo Alto meth lab bust  May 6, 2006
...busted a major methamphetamine laboratory in East Palo Alto on Friday, recovering $25,000, assault rifles and tens of thousands of pseudoephedrine pills -- a ... - San Jose Mercury News,

Man who grabbed armfuls of medicine gets 10 years  May 1, 2006
...-- A man who grabbed all the pseudoephedrine off a Wal-Mart pharmacy shelf in Goodland and ran out the door was sentenced Monday to 10 years in prison. ... - KCTV5 News,

Over-the-counter intelligence  May 2, 2006
...into law by President Bush two months ago, a reauthorization of the Patriot Act forces retailers to move cold medicine containing pseudoephedrine behind the ... - MetroWest Daily News,

Dosage Forms tablets, Oral liquid, nasal spray
Drug_Category Adrenergic Agents; Vasoconstrictor Agents; Bronchodilator Agents; Central Nervous System Agents; Sympathomimetic; ATC:R01BA02
Absorption Pseudoephedrine is readily and almost completely absorbed from the GI tract and there is no evidence of first-pass metabolism
Interactions Interactions for Pseudoephedrine:

MAO inhibitors and beta adrenergic blockers increase the effects of pseudoephedrine. Sympathomimetics may reduce the antihypertensive effects of methyldopa, mecamylamine, reserpine and veratrum alkaloids.

Toxicity Not Available
Organisms Affected Humans and other mammals
Chemical IUPAC Name 2-methylamino-1-phenyl-propan-1-ol
Chemical Formula C10H15NO
Molecular Weight 165.232 g/mol
Smiles String CC(C(C1=CC=CC=C1)O)NC
Melting Point 117 - 118 °C
Water Solubility 7mg/L
State Solid
LogP/Hphobicity 1.507
Isoelectric Point Not Available
Biotransformation Hepatic
Half Life 4 hours
Protein Binding [%] Pseudoephedrine did not bind to human plasma proteins over the concentration range of 50 to 2000 ng/mL
RxList Link RXlist
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Drug Reference http://www.drugs.com/cons/Pseudoephedrine.html
http://www.rxlist.com/cgi/generic/sudafed.htm
Drug Type Approved Drug
Accession No APRD00634
CAS Registry Number 90-82-4
KEGG Compound ID Not Available
PubChem ID SID:150051
PharmGKB ID Not Available
SwissProt ID Not Available
GenBank ID Not Available
Drug ID Number [DIN] 2239134

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