Oxytocin drug data and news

Oxytocin drug data, resources, and news articles (when available). Onconews.org provides news on cancer research. This section, which includes profiles on medicines that may or not be cancer-related is in beta form. If things run smoothly we will be releasing a new format late in the summer of 2006.

Generic name Oxytocin
Brand Names/Synonyms Oxytocin; Pitocin; Syntocinon; Oxytocin (BAM Biotech); Pitocin (Parke-Davis); Syntocinon (Sandoz)
Indication To assist in labor, elective labor induction, uterine contraction induction
Sponsored links
Description Synthetic 9 residue cyclic peptide. The hormone is prepared synthetically to avoid possible contamination with vasopressin (ADH) and other small polypeptides with biologic activity.
Pharmacology Used to induce labor or to enhance uterine contractions during labor. Uterine motility depends on the formation of the contractile protein actomyosin under the influence of the Ca2+-dependent phosphorylating enzyme myosin light-chain kinase. Oxytocin promotes contractions by increasing the intracellular Ca2+, which in turn activates myosins light chain kinase.. Oxytocin has specific receptors in the muscle llining of the uterus and the receptor concentration increases greatly during pregnancy, reaching a maximum in early labor at term.
Mechanism Of Action Binds the oxytocin receptor which leads to an increase in intracellular calcium levels.
Oxytocin News
(When available)

Quiz: What is the truth about trusting?  16 May 2006
4. TRUE. The hormone oxytocin, which occurs naturally in the brain and helps regulate emotion, has been shown in studies to lead people to be more trusting. ... - Seattle Post Intelligencer

Balloon Tamponade Works When Oxytocin and Other Uterotonics Fail ...  May 11, 2006
Joseph Hospital, Denver, Colorado, and colleagues conducted a 2-year retrospective review of 24 cases who had received oxytocin; 20 of these patients had ... - DG News

Oxytocin and Maternal Recognition of Pregnancy  May 11, 2006
In sheep and cattle, at the end of the estrous cycle, the CL produces the hormone oxytocin. Oxytocin then stimulates the uterus to produce PGF. ... - TheHorse.com,

Oxytocin nasal spray does not boost milk output  May 5, 2006
NEW YORK (Reuters Health) - A nasal spray containing the hormone oxytocin, which is essential to the production and flow of breast milk, does not improve milk ... - Reuters.uk,

Induction Shortens Active Phase of Labor but Increases Cesarean ...  May 15, 2006
This group was further divided into 735 women who had oxytocin induction without cervical pre-ripening, 61 women who had pre-induction cervical ripening ... - Medscape (subscription)

Contraction Stress Test  May 10, 2006
Find out more here about the contraction stress test (aka the "oxytocin challenge test" or simply "stress test"), used in the third trimester to check how the ... - Pregnancy and Baby,

Induction or Augmentation of Labor Raises Risk of Chorioamnionitis ...  May 10, 2006
There were 1717 (23.3%) patients who underwent labor induction, 1159 with oxytocin, 457 with misoprostol and 69 with Foley catheter. ... - DG News

Mothers rock! They swing the cradle, fry the bacon and build the ...  May 14, 2006
Resilience: Oxytocin - a powerful hormone abundant in mothers - so effectively combats stress and clears the way for improved learning, that scientists are ... - Jackson Sun,

All in the mind  May 5, 2006
If we truly feel bonded and connected with the person, our brain's emotional centres will secrete high levels of oxytocin, the chemical associated with keeping ... - Edmonton Sun,

A Mother’s Touch  May 12, 2006
...methyl groups attach to the DNA, preventing the production of certain hormones key to future mothering behaviors, including estrogen and oxytocin, also known ... - ScienCentral News,

Non-Stress Test (NST)  May 10, 2006
...sleeping"; if, after stimulation, the fetus still does not react, it may be necessary to perform a "contraction stress test" (aka the "oxytocin challenge test ... - Pregnancy and Baby,

My doula is a dude  May 9, 2006
The hormone oxytocin, sometimes called the "love hormone," is an element in this test - it is produced during labor as well as sexual intercourse. ... - Ha'aretz,

Health Watch: Finding Good Health In Pets Instead Of Pills  May 12, 2006
...being. “Such as phenethylamine, dopamine, endorphins -- that's the so-called 'runner's high,' oxytocin and prolaxin," said Creagan. ... - KFOXtv.com,

Instant Expert  Apr 28, 2006
...excitement. Other hormones, oxytocin and vasopressin, kick in later and appear to be crucial for forming long-term partnerships. ... - New Scientist (subscription),

Excerpt: 'Fitness Unleashed'  May 3, 2006
You may have read that when you pet your dog, your blood pressure drops and the level of the feel-good hormones such as oxytocin, prolactin, and serotonin in ... - ABC News

Bigger than potato chips  May 8, 2006
A wildlife veterinarian removed the eggs from the injured mothers, some by surgery and some by induction with the drug oxytocin. ... - Savannah Morning News,

World Experts Gather To Reduce Burden Of Premature Birth  May 1, 2006
Tractocile was developed to specifically target oxytocin receptors in the mother's uterus to stop preterm labour contractions and has a rapid onset of action.[i ... - Medical News Today (press release),

The secret of being in rude health is intercourse  Apr 22, 2006
Such sex has been linked, in women, to a heightened emotional awareness, possibly because the "love hormone" oxytocin is released. ... - The Age,

Caesareans up by 72% as expectant mums are ‘too posh to push’  Apr 29, 2006
Hospital doctors operate a conveyor belt system of active management; use oxytocin to make contractions come quicker and stronger and readily resort to the use ... - The Sunday Times,

Tom Cruise to snack on placenta after baby's birth?  Apr 18, 2006
...childbirth. The afterbirth product is rich in prostaglandins and also contains oxytocin that eases postpartum depression. While ... - Earthtimes.org

Sex is in the air  Apr 22, 2006
...stress for up to a week. This was attributed to the release of the hormone oxytocin during intercourse. When Gordon House is finally ... - Jamaica Observer,

Popular Pill for Inducing Labor Found Effective, But Concerns ...  Apr 18, 2006
...misoprostol administered orally versus vaginally and compared oral misoprostol with vaginal use of the prostaglandin dinoprostone and with intravenous oxytocin ... - Health Behavior News Service

Low Stairway to Heaven  Apr 17, 2006
Our brain registers such images and associates them with sex, triggering the release of chemicals like oxytocin and dopamine, which are also released during ... - CU Columbia Spectator,

Mummy knows best  Apr 17, 2006
But I also breastfed both my children which, according to Ellison, should have boosted levels of the hormone oxytocin, thus permanently reducing my reactivity ... - Times Online,

Buddhism and the art of brain science  Apr 25, 2006
One of these peptides, called oxytocin, has been associated with a general feeling of well-being, even a sense of trust in social situations. ... - ParamusPost.com,

Surprise: sex is good for you  Apr 24, 2006
...a week. Brody guessed the release by both partners of the so-called "love hormone" oxytocin accounted for the calming effect. It ... - Stuff.co.nz,

Hollywood reduces effort needed for marriage  Apr 26, 2006
...attachment -- begins. Cobb said attachment produces oxytocin in the brain, which causes one to feel very calm and soothed. Fifty ... - Baylor University The Lariat Online,

Love special: Six ways to woo your lover  Apr 27, 2006
A nasal spray containing the hormone oxytocin can make people trust you - an important part of any relationship - though there's no evidence yet to suggest it ... - New Scientist (subscription),

Is it safe to have sex?  Apr 19, 2006
Orgasms or even intercourse itself can cause the uterus to contract and the abdomen to harden due to the release of the hormone oxytocin. ... - Health24.com,

Brain Differences Could Explain Why Males And Females Experience ...  Apr 21, 2006
CBN studies have led to breakthrough treatment for anxiety-related disorders and new understanding of the neurochemicals vasopressin and oxytocin in social ... - Medical News Today (press release),

Dosage Forms Not Available
Drug_Category Anti-tocolytic Agents; Labor Induction Agents
Absorption Not Available
Interactions Not Available
Toxicity Not Available
Organisms Affected Humans and other mammals
Chemical IUPAC Name Oxytocin
Chemical Formula C43H67N11O13S2
Molecular Weight 1010.1
Smiles String CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)N1)CC2=CC=C(C=C2)O)N)C(=O)N3CCCC3C(=O)NC(CC(C)C)C(=O)NCC(=O)N)CC(=O)N)CCC(=O)N
Melting Point Not Available
Water Solubility Not Available
State Transparent, slightly viscous, aqueous liquid
LogP/Hphobicity -2.789
Isoelectric Point 5.51
Biotransformation Not Available
Half Life 1-6 min
Protein Binding [%] 30%
RxList Link RXlist
Sponsored links
Drug Reference http://www.drugs.com/cons/Oxytocin.html
http://www.rxlist.com/cgi/generic3/oxytocin.htm
Drug Type Approved Drug
Accession No BIOD00016
CAS Registry Number 50-56-6
KEGG Compound ID C00746
PubChem ID SID:4008
PharmGKB ID PA450760
SwissProt ID Not Available
GenBank ID Not Available
Drug ID Number [DIN] Not Available

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