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Oxytocin
drug data and news
Oxytocin drug data, resources, and news articles (when available). Onconews.org provides news on cancer research. This section, which includes profiles on medicines that may or not be cancer-related is in beta form. If things run smoothly we will be releasing a new format late in the summer of 2006.
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| Generic name | Oxytocin | ||
| Brand Names/Synonyms | Oxytocin; Pitocin; Syntocinon; Oxytocin (BAM Biotech); Pitocin (Parke-Davis); Syntocinon (Sandoz) | ||
| Indication | To assist in labor, elective labor induction, uterine contraction induction | ||
| Sponsored links | Description | Synthetic 9 residue cyclic peptide. The hormone is prepared synthetically to avoid possible contamination with vasopressin (ADH) and other small polypeptides with biologic activity. | |
| Pharmacology | Used to induce labor or to enhance uterine contractions during labor. Uterine motility depends on the formation of the contractile protein actomyosin under the influence of the Ca2+-dependent phosphorylating enzyme myosin light-chain kinase. Oxytocin promotes contractions by increasing the intracellular Ca2+, which in turn activates myosins light chain kinase.. Oxytocin has specific receptors in the muscle llining of the uterus and the receptor concentration increases greatly during pregnancy, reaching a maximum in early labor at term. | ||
| Mechanism Of Action | Binds the oxytocin receptor which leads to an increase in intracellular calcium levels. | ||
| Oxytocin News (When available) |
Quiz: What is the truth about trusting? 16 May 2006 Balloon Tamponade Works When Oxytocin and Other Uterotonics Fail ... May 11, 2006 Oxytocin and Maternal Recognition of Pregnancy May 11, 2006 Oxytocin nasal spray does not boost milk output May 5, 2006 Induction Shortens Active Phase of Labor but Increases Cesarean ... May 15, 2006 Contraction Stress Test May 10, 2006 Induction or Augmentation of Labor Raises Risk of Chorioamnionitis ... May 10, 2006 Mothers rock! They swing the cradle, fry the bacon and build the ... May 14, 2006 All in the mind May 5, 2006 A Mother’s Touch May 12, 2006 Non-Stress Test (NST) May 10, 2006 My doula is a dude May 9, 2006 Health Watch: Finding Good Health In Pets Instead Of Pills May 12, 2006 Instant Expert Apr 28, 2006 Excerpt: 'Fitness Unleashed' May 3, 2006 Bigger than potato chips May 8, 2006 World Experts Gather To Reduce Burden Of Premature Birth May 1, 2006 The secret of being in rude health is intercourse Apr 22, 2006 Caesareans up by 72% as expectant mums are ‘too posh to push’ Apr 29, 2006 Tom Cruise to snack on placenta after baby's birth? Apr 18, 2006 Sex is in the air Apr 22, 2006 Popular Pill for Inducing Labor Found Effective, But Concerns ... Apr 18, 2006 Low Stairway to Heaven Apr 17, 2006 Mummy knows best Apr 17, 2006 Buddhism and the art of brain science Apr 25, 2006 Surprise: sex is good for you Apr 24, 2006 Hollywood reduces effort needed for marriage Apr 26, 2006 Love special: Six ways to woo your lover Apr 27, 2006 Is it safe to have sex? Apr 19, 2006 Brain Differences Could Explain Why Males And Females Experience ... Apr 21, 2006 | ||
| Dosage Forms | Not Available | ||
| Drug_Category | Anti-tocolytic Agents; Labor Induction Agents | ||
| Absorption | Not Available | ||
| Interactions | Not Available | ||
| Toxicity | Not Available | ||
| Organisms Affected | Humans and other mammals | ||
| Chemical IUPAC Name | Oxytocin | ||
| Chemical Formula | C43H67N11O13S2 | ||
| Molecular Weight | 1010.1 | ||
| Smiles String | CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)N1)CC2=CC=C(C=C2)O)N)C(=O)N3CCCC3C(=O)NC(CC(C)C)C(=O)NCC(=O)N)CC(=O)N)CCC(=O)N | ||
| Melting Point | Not Available | ||
| Water Solubility | Not Available | ||
| State | Transparent, slightly viscous, aqueous liquid | ||
| LogP/Hphobicity | -2.789 | ||
| Isoelectric Point | 5.51 | ||
| Biotransformation | Not Available | ||
| Half Life | 1-6 min | ||
| Protein Binding [%] | 30% | ||
| RxList Link | RXlist | ||
| Sponsored links | |||
| Drug Reference |
http://www.drugs.com/cons/Oxytocin.html http://www.rxlist.com/cgi/generic3/oxytocin.htm | ||
| Drug Type | Approved Drug | ||
| Accession No | BIOD00016 | ||
| CAS Registry Number | 50-56-6 | ||
| KEGG Compound ID | C00746 | ||
| PubChem ID | SID:4008 | ||
| PharmGKB ID | PA450760 | ||
| SwissProt ID | Not Available | ||
| GenBank ID | Not Available | ||
| Drug ID Number [DIN] | Not Available |
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