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Isoetharine
drug data and news
Isoetharine drug data, resources, and news articles (when available). Onconews.org provides news on cancer research. This section, which includes profiles on medicines that may or not be cancer-related is in beta form. If things run smoothly we will be releasing a new format late in the summer of 2006.
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| Generic name | Isoetharine | ||
| Brand Names/Synonyms | Beta-2; Bronkometer; Bronkosol; CHEMBANK4338; Dey-Lute Isoetharine; Dilabron; Etyprenaline; I3639; Isoetarin; Isoetarina [Inn-Spanish]; Isoetarine; Isoetarinum [Inn-Latin]; Isoetharine; Isoetharine Hcl; Isoetharine Hcl S/F; Isoetharine Mesylate; Isoetharine [Usan:Ban]; Neoisuprel; Win 3406; Win-3406 | ||
| Indication | For use in management of asthma, wheezing, and chronic asthmatic bronchitis. | ||
| Sponsored links | Description | Not Available | |
| Pharmacology | Isoetharine is a relatively selective beta2-adrenergic bronchodilator. Isoetharine is indicated for the relief of bronchospasm associated with chronic obstructive pulmonary disease. Adrenergic bronchodilators are breathed in through the mouth to open up the bronchial tubes (air passages) of the lungs. | ||
| Mechanism Of Action | The pharmacologic effects of isoetharine are attributable to stimulation through beta-adrenergic receptors of intracellular adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic AMP. Increased cyclic AMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells, especially from mast cells. | ||
| Isoetharine News (When available) |
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| Dosage Forms | Inhalation aerosol, inhalation solution | ||
| Drug_Category | Bronchodilator Agents; Adrenergic beta-Agonists | ||
| Absorption | Not Available | ||
| Interactions |
Interactions for Isoetharine: May interact with the following: beta-adrenergic blocking agents (these medicines may make your condition worse and prevent the adrenergic bronchodilators from working properly) and disopyramide, quinidine, phenothiazines, and procainamide (these medicines may increase the risk of heart problems). | ||
| Toxicity | Signs of overdose include tachycardia, palpitations, nausea, headache, and epinephrine-like side effects. | ||
| Organisms Affected | Humans and other mammals | ||
| Chemical IUPAC Name | 4-[1-hydroxy-2-(1-methylethylamino)butyl]benzene-1,2-diol | ||
| Chemical Formula | C13H21NO3 | ||
| Molecular Weight | 239.311 g/mol | ||
| Smiles String | CCC(C(C1=CC(=C(C=C1)O)O)O)NC(C)C | ||
| Melting Point | Not Available | ||
| Water Solubility | Appreciable | ||
| State | Solid | ||
| LogP/Hphobicity | 2.125 | ||
| Isoelectric Point | Not Available | ||
| Biotransformation | Not Available | ||
| Half Life | Not Available | ||
| Protein Binding [%] | Not Available | ||
| RxList Link | Not Available>RXlist | ||
| Sponsored links | |||
| Drug Reference | http://www.drugs.com/cons/Isoetharine.html | ||
| Drug Type | Approved Drug | ||
| Accession No | APRD00750 | ||
| CAS Registry Number | 530-08-5 | ||
| KEGG Compound ID | C07053 | ||
| PubChem ID | SID:9265 | ||
| PharmGKB ID | PA450103 | ||
| SwissProt ID | Not Available | ||
| GenBank ID | Not Available | ||
| Drug ID Number [DIN] | Not Available |
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