Human Serum Albumin drug data and news

Human Serum Albumin drug data, resources, and news articles (when available). Onconews.org provides news on cancer research. This section, which includes profiles on medicines that may or not be cancer-related is in beta form. If things run smoothly we will be releasing a new format late in the summer of 2006.

Generic name Human Serum Albumin
Brand Names/Synonyms Serum albumin precursor; Albutein (Alpha Therapeutic Corp)
Indication For treatment of severe blood loss, hypervolemia, hypoproteinemia
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Description Human serum albumin isolated from expired blood plasma
Pharmacology Regulates the colloidal osmotic pressure of blood. It is used to increase the circulating plasma volume, thereby reducing hemoconcentrtion and blood viscosity. Also used as a transport protein that binds naturally occurring, therapeutic and toxic materials in circulation.
Mechanism Of Action Acts as a high molecular weight, very soluble osmolyte
Human Serum Albumin News
(When available)
New stem-cell medium seems safer -- study  Jan 3, 2006
Monsters and Critics.com, ...'We replaced the calf serum with human serum albumin, but it didn`t work well enough, so we supplemented it with lipids and five separate factors: human TGF ...

Dosage Forms SOLUTION
Drug_Category Serum substitutes; blood derivatives (16:00.00)
Absorption Not Available
Interactions Not Available
Toxicity Not Available
Organisms Affected Humans and other mammals
Chemical IUPAC Name Human serum albumin
Chemical Formula C2936H4624N786O889S41
Molecular Weight 66472.2
Smiles String Not Available
Melting Point 62 oC (Flora, K. et al., Biophys J. 75:1084-1096 (1998))
Water Solubility Not Available
State Transparent, slightly viscous, aqueous liquid
LogP/Hphobicity -0.395
Isoelectric Point 5.67
Biotransformation Not Available
Half Life Not Available
Protein Binding [%] Not Available
RxList Link RXlist
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Drug Reference http://www.rxlist.com/cgi/generic3/albumin.htm
Drug Type Approved Drug
Accession No BIOD00059
CAS Registry Number 9048-49-1
KEGG Compound ID Not Available
PubChem ID Not Available
PharmGKB ID Not Available
SwissProt ID ALBU_HUMAN (P02768)
GenBank ID M12523
Drug ID Number [DIN] 427675

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