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Framycetin
drug data and news
Framycetin drug data, resources, and news articles (when available). Onconews.org provides news on cancer research. This section, which includes profiles on medicines that may or not be cancer-related is in beta form. If things run smoothly we will be releasing a new format late in the summer of 2006.
| Generic name |
Framycetin
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| Brand Names/Synonyms |
Actilin; Actiline; Antibiotique; Dekamycin V; Enterfram; Fradiomycin B; Framycetin; Framycetinum [Inn-Latin]; Framygen; NEOMYCIN B; Neamin; Neamine; Nebramycin X; Negamicin; Neomycin A; Neomycin B; Soframycin; Soframycin Ophthalmic; Soframycine; Streptothricin B |
| Indication |
For Skin and subcutaneous tissue infections;Infective otitis externa;Antibiotic cover (surgery) |
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Description |
Not Available |
| Pharmacology |
Used for the treatment of bacterial eye infections such as conjunctivitis. Framycetin is a broad spectrum aminoglycoside antibiotic. It is not active against fungi, viruses and most kinds of anaerobic bacteria. |
| Mechanism Of Action |
Inhibits protein synthesis in susceptible bacteria by binding to the 30S subunit of the bacterial ribosome and inhibiting peptide chain elongation. |
Framycetin News
(When available) |
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| Dosage Forms |
DROPS |
| Drug_Category |
Anti-bacterial Agents; Anti-bacterial Agents; ATC:D09AA01; ATC:R01AX08; ATC:S01AA07 |
| Absorption |
Not Available |
| Interactions |
Not Available |
| Toxicity |
Not Available |
| Organisms Affected |
Enteric bacteria and other eubacteria |
| Chemical IUPAC Name |
5-amino-2-(aminomethyl)-6-[5-[3,5-diamino-2-[3-amino-6-(aminomethyl)-4,5-dihydroxy-tetrahydropyran-2-yl]oxy-6-hydroxy-cyclohexoxy]-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl]oxy-tetrahydropyran-3,4-diol |
| Chemical Formula |
C23H46N6O13 |
| Molecular Weight |
614.644 g/mol |
| Smiles String |
C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)N)OC3C(C(C(O3)CO)OC4C(C(C(C(O4)CN)O)O)N)O)O)N |
| Melting Point |
Not Available |
| Water Solubility |
Not Available |
| State |
Solid |
| LogP/Hphobicity |
-9.895 |
| Isoelectric Point |
Not Available |
| Biotransformation |
Not Available |
| Half Life |
Not Available |
| Protein Binding [%] |
Not Available |
| RxList Link |
Not Available>RXlist |
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| Drug Reference |
http://www.drugs.com/cons/Framycetin.html |
| Drug Type |
Approved Drug |
| Accession No |
APRD00618 |
| CAS Registry Number |
119-04-0 |
| KEGG Compound ID |
Not Available |
| PubChem ID |
SID:151525 |
| PharmGKB ID |
PA10085 |
| SwissProt ID |
Not Available |
| GenBank ID |
Not Available |
| Drug ID Number [DIN] |
2224887
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