Doxorubicin drug data and news

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International Approvals: Rotarix, Hycamtin, Pulmicort HFA  06 Mar 2006
Results of the first study showed topotecan to be similarly effective to a 3-drug regimen (cyclophosphamide, doxorubicin, and vincristine [CAV]) with respect ... - Medscape (subscription)

Q&A: Breast Cancer During Pregnancy  06 Mar 2006
The treatment is called FAC chemotherapy (5-flurouracil, doxorubicin, and cyclophosphamide). The chemotherapy was given during the second and third trimesters. ... - CancerWise

Getting warmer in bid to kill tumors  06 Mar 2006
Mixed in with the water is a chemotherapy drug, doxorubicin. The liposome is designed to be stable at body temperature but to burst when heated. ... - Boston Globe,

Liposomal Doxorubicin Plus Cyclophosphamide Shows Promise in ...  Feb 3, 2006
PARIS, FRANCE -- February 3, 2006 -- The combination of liposome-encapsulated doxorubicin (Myocet) plus cyclophosphamide has demonstrated early favorable ... - DG News

Doxil® in the VAD Regimen for Myeloma Confirmed Less Toxic Than ...  Feb 28, 2006
A US multicenter trial has reported that a regimen of Doxil (pegylated liposomal doxorubicin), vincristine and dexamethasone is associated with less toxicity ... - Cancer Consultants (press release),

Alfacell Achieves Full Patient Enrollment Milestone for the ...  Feb 27, 2006
...in the ONCONASE UMM study, including newly-diagnosed and refractory patients treated with ONCONASE as a single agent and in combination with doxorubicin. ... - PR Newswire (press release),

Doxil® Associated with Fewer Heart Side Effects than Adriamycin® ...  Feb 14, 2006
According to results recently published in the journal Cancer, the use of the chemotherapy agent Doxil® (pegylated liposomal doxorubicin) in place of ... - Cancer Consultants (press release),

ARIAD Initiates First Clinical Trial of Oral AP23573 in ...  Feb 14, 2006
...initiation of enrollment of advanced cancer patients in a Phase Ib clinical trial of its novel mTOR inhibitor, AP23573, in combination with doxorubicin - a long ... - Genetic Engineering News,

Procyon Presents Preclinical Results with its Novel Tumor ...  Feb 7, 2006
...today that preclinical results with its novel tumor vasculature targeting drug, TVT-Dox (Tumor Vasculature Targeting liposomal doxorubicin), were presented at ... - Genetic Engineering News,

Simultaneous HIV therapy and chemotherapy for lymphoma effective ...  Feb 28, 2006
German doctors wished to assess the safety and efficacy of using combined chemotherapy consisting of cyclophosamide, doxorubicin, vincristine and prednisone at ... - Aidsmap,

Neoadjuvant Sarcoma Chemotherapy Results in High Toxicity Levels  Mar 1, 2006
The patients received three cycles of neoadjuvant modified mesna, doxorubicin, ifosfamide and dacarbazine (MAID), interdigitated radiotherapy and following ... - Cancerpage.com,

Neoadjuvant Chemotherapy and Radiotherapy Promising for Large Soft ...  Mar 3, 2006
All were scheduled to receive neoadjuvant concomitant radiotherapy and chemotherapy with MAID (mesna, ifosfamide, doxorubicin and dacarbazine). ... - Cancer Consultants (press release),

AIDS-related Lymphoma Outcome Improved By Combination Therapy  Mar 2, 2006
They are treated with chemotherapy, often consisting of a multi-drug regimen using cyclophosphamide, doxorubicin, vincristine and prednisone (CHOP). ... - Medical News Today (press release),

Combo Therapy Fights AIDS-Linked Lymphoma  Feb 27, 2006
...study included 72 HIV patients with AIDS-related lymphoma treated with a multi-drug chemotherapy called CHOP (cylcophosphamide, doxorubicin, vincristine, and ... - Forbes

Celsion Announces 1-for-15 Reverse Stock Split; Stockholder ...  Feb 27, 2006
We have demonstrated our ability to initiate and execute a development program for our heat activated liposomal doxorubicin drug, ThermoDox(TM), including ... - Genetic Engineering News,

Anti-angiogenesis Therapy With Avastin (Bevacizumab): Presented at ...  Feb 21, 2006
...breast cancer is evaluating adjuvant bevacizumab 10 mg/kg every 14 days for four cycles in combination with and following both doxorubicin/cyclophosphamide 60 ... - DG News

CHOP Plus HAART Improves Outcome of AIDS-Related Lymphoma  Feb 28, 2006
NEW YORK FEB 27, 2006 (Reuters Health) - In patients with AIDS-related lymphoma, combined treatment with cyclophosphamide, doxorubicin, vincristine, and ... - Cancerpage.com,

Pro-Pharmaceuticals to Present Abstract & Poster at Mass ...  Mar 2, 2006
The Company has been conducting clinical and pre-clinical studies with 5-FU, leucovorin, irinotecan, doxorubicin, oxaliplatin, paclitaxel, cisplatin, and ... - Genetic Engineering News,

Interim Combined Analysis Shows Benefits of Adjuvant trastuzumab ...  Feb 20, 2006
...adjuvant trastuzumab therapy, saying that their similar control and concurrent treatment groups compared standard chemotherapy (doxorubicin/cyclophosphamide 60 ... - DG News

ImClone’s Erbitux Receives FDA Label In Head And Neck Cancer  Mar 2, 2006
...backed away from its takeover of Indianapolis-based device maker Guidant Corp., and might be looking for an oncology drug to market with its Doxil (doxorubicin ... - BioWorld Online (subscription),

Intraductal Therapy Effective in Breast Cancer Model  Feb 8, 2006
...evaluated the ability of intraductally administered 4-hydroxytamoxifen - the active metabolite of tamoxifen - and pegylated liposomal doxorubicin to prevent ... - Cancerpage.com,

Small molecules overcome drug resistance in cancers associated ...  Feb 14, 2006
The researchers used a screening method to look for compounds that potentiate chemotherapeutic effectiveness of the agent doxorubicin in E6-expressing colon ... - innovations report,

Genentech, Biogen Idec Gain Approval Of Rituxan In RA  Mar 1, 2006
...combination agent in diffuse large B-cell, CD20-positive, non-Hodgkin’s lymphoma in combination with CHOP (cyclophosphamide, doxorubicin, vincristine and ... - BioWorld Online (subscription),

Anthracyclines Linked with Damage to Blood Vessels  Feb 24, 2006
These drugs, which include doxorubicin and daunorubicin, are used to treat a variety of cancers, including Hodgkin’s lymphoma, sarcomas, and breast cancer. ... - Cancer Consultants (press release),

Ariad Initiates Trial of Anticancer Candidate  Feb 15, 2006
...has initiated enrollment of advanced cancer patients in a phase Ib clinical trial of its candidate, AP23573, in combination with doxorubicin - the mainstay of ... - International News Service,

Optimising Herceptin-based Therapy in HER2-positive Metastatic ...  Feb 22, 2006
...rated (IHC) 2+/3+ patients depended on their status for prior anthracycline treatment, and involved comparisons across doxorubicin/cyclophosphamide (AC) with ... - DG News

What Can Xeloda (capecitabine) Add to Neoadjuvant Chemotherapy? ...  Feb 22, 2006
...phase 3 trial, which compared neoadjuvant capecitabine/docetaxel 1000/75 mg/m 2 three times weekly for four cycles (XT) versus doxorubicin/cyclophosphamide 60 ... - DG News

Xeloda Expands Options in Adjuvant Treatment of Breast Cancer ...  Feb 21, 2006
Indeed, to provide further safety data, Dr. Poole referred to trial data that will be looking at doxorubicin/ cyclophosphamide (AC) versus capecitabine plus ... - DG News

BCIRG 006 Shows Trastuzumab (Herceptin) Improves Disease-free ...  Feb 20, 2006
...trial that compared a docetaxel with carboplatin and trastuzumab (DCT; 6 cycles, with 1 year of trastuzumab) regimen with doxorubicin/cyclophosphamide (AC; 4 ... - DG News

The importance of coenzyme Q10  Feb 19, 2006
Possible drug interactions include the following:Daunorubicin and Doxorubicin (chemotherapy agents) - CoQ10 may reduce the toxic effects on the heart; blood ... - Zanesville Times Recorder,

RITUXAN: FIRST FDA-APPROVED TREATMENT TO IMPROVE SURVIVAL FOR ...  Feb 22, 2006
...of patients with diffuse large B-cell CD20-positive, non-Hodgkin’s lymphoma (DLBCL), in combination with CHOP (cyclophosphamide, doxorubicin, vincristine and ... - PR Newswire (press release),

Celsion Signs Agreement With Fast Track Systems  Feb 13, 2006
Celsion plans to initiate a global multi-site Phase II/III clinical study to investigate the use of ThermoDox™, an encapsulation of doxorubicin in Celsion's ... - Market Wire (press release)

Breakthrough In The Design Of New Drugs - New Way Of Recognising ...  Feb 17, 2006
...the filling. An early example of such a drug used to treat cancer was doxorubicin (trade name ‘Adriamycin' or ‘Rubex'). This ... - Medical News Today (press release),

Rituxan Gets Added Clearance  Feb 13, 2006
...receiving chemo alone. CHOP chemothrapy consists of treatment with cyclophosphamide, doxorubicin, vincristine and prednisone. In one ... - TheStreet.com

GlaxoSmithKline Application Accepted by the FDA to Expand Use of ...  Feb 17, 2006
...weeks), cisplatin plus Hycamtin (Hycamtin 0.75 mg/m2 d1-3 plus cisplatin 50 mg/m2 d1 q 3 weeks), or MVAC (methotrexate, vinblastine, doxorubicin, and cisplatin ... - Finanzen.net,

Rituximab maintenance therapy dramatically improves survival for ...  Feb 15, 2006
20981 trial, 465 patients with relapsed and refractory indolent NHL were randomised to receive either 3-weekly cyclophosphamide, doxorubicin, vincristine, and ... - Innovations-Report,

Management Changes at Ecopia  Feb 17, 2006
Just like well-known chemotherapies such as doxorubicin and mitomycin C, ECO-4601 comes from microorganisms that live in common soil. ... - CCNMatthews (press release),

No Sign of Heart Problems in Children Exposed to Mother’s ...  Feb 14, 2006
...non-Hodgkin’s lymphoma (33 women). The most commonly administered anthracycline was doxorubicin. A previous report from this study ... - Cancer Consultants (press release),

Stocks to Watch  Feb 13, 2006
...(BIIB) that the US Food and Drug Administration approved the Rituxan treatment in combination with cyclophosphamide, doxorubicin, vincristine and prednisone ... - Asbury Park Press,

Updated Results: Velcade® Improves Survival Over Dexamethasone in ...  Feb 8, 2006
This is a remarkable finding since the complete remission rate to first-line treatment with VAD (Oncovin® (vincristine), doxorubicin, and dexamethasone) for ... - Cancer Consultants (press release),

Doxil®/Eloxatin® May Provide a Treatment Option in Advanced ...  Feb 6, 2006
...to a recent article published in Gynecologic Oncology, the chemotherapy combination consisting of Doxil® (pegylated liposomal doxorubicin) plus Eloxatin ... - Cancer Consultants (press release),

MultiVu Video Feed: Rituxan: First FDA-Approved Treatment to ...  Feb 10, 2006
...of patients with diffuse large B-cell CD20-positive, non-Hodgkin's lymphoma (DLBCL), in combination with CHOP (cyclophosphamide, doxorubicin, vincristine and ... - PR Newswire (press release),

Rituxan® Approved for Initial Treatment of Diffuse Large B-Cell ...  Feb 14, 2006
The three trials include nearly 2,000 individuals who were treated with CHOP (cyclophosphamide, doxorubicin, vincristine, prednisone) or other anthracycline ... - Cancer Consultants (press release),

Adjuvant Chemotherapy Effective for Advanced Endometrial Cancer  Feb 14, 2006
Researchers affiliated with the Gynecologic Oncology Study Group have reported that chemotherapy with Adriamycin® (doxorubicin) and Platinol® (cisplatin) was ... - Cancer Consultants (press release),

ADVENTRX CoFactor Phase IIb Trial Surpasses 50% Enrollment ...  Feb 14, 2006
Phase III clinical trial would be a randomized parallel group trial in patients with advanced breast cancer who have completed taxane and doxorubicin treatment ... - PR Newswire (press release),

IV Hycamtin Receives European Marketing Approval as Treatment for ...  Feb 1, 2006
The first study (protocol 090) compared the safety and efficacy of Hycamtin to the triple combination cyclophosphomide, doxorubicin and vincristine (CAV) in ... - DG News

Pro-Pharmaceuticals Receives 'Compassionate Use' IND for Use of ...  Feb 2, 2006
The Company has been conducting clinical studies with 5-FU, leucovorin, irinotecan, doxorubicin, oxaliplatin, paclitaxel, cisplatin, and bevacizumab (AVASTIN(R ... - International News Service,

No formal drug interaction studies have been conducted with DOXIL^® . Until specific compatibility data are available, it is not recommended that DOXIL^® be mixed with other drugs. DOXIL^® may interact with drugs known to interact with the conventional formulation of doxorubicin HCl.