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Dopamine
drug data and news
Dopamine drug data, resources, and news articles (when available). Onconews.org provides news on cancer research. This section, which includes profiles on medicines that may or not be cancer-related is in beta form. If things run smoothly we will be releasing a new format late in the summer of 2006.
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| Generic name | Dopamine | ||
| Brand Names/Synonyms | ASL 279; DA; Deoxyepinephrine; Dopamin; Dopamine; Dopamine Hcl; Dopamine Hcl in Dextrose 5%; Dophamine; Hydroxytyramin; Hydroxytyramine; Intropin; Oxytyramine; Revimine | ||
| Indication | For the correction of hemodynamic imbalances present in the shock syndrome due to myocardial infarction, trauma, endotoxic septicemia, open-heart surgery, renal failure, and chronic cardiac decompensation as in congestive failure | ||
| Sponsored links | Description | Not Available | |
| Pharmacology | Dopamine is a natural catecholamine formed by the decarboxylation of 3,4-dihydroxyphenylalanine (DOPA). It is a precursor to norepinephrine in noradrenergic nerves and is also a neurotransmitter in certain areas of the central nervous system, especially in the nigrostriatal tract, and in a few peripheral sympathetic nerves. Dopamine produces positive chronotropic and inotropic effects on the myocardium, resulting in increased heart rate and cardiac contractility. This is accomplished directly by exerting an agonist action on beta-adrenoceptors and indirectly by causing release of norepinephrine from storage sites in sympathetic nerve endings. | ||
| Mechanism Of Action | Dopamine is a precursor to norepinephrine in noradrenergic nerves and is also a neurotransmitter in certain areas of the central nervous system. Dopamine produces positive chronotropic and inotropic effects on the myocardium, resulting in increased heart rate and cardiac contractility. This is accomplished directly by exerting an agonist action on beta-adrenoceptors and indirectly by causing release of norepinephrine from storage sites in sympathetic nerve endings. | ||
| Dopamine News (When available) |
Pittsburgh Tribune-Review, ...affects as many as 1.5 million Americans -- including actor Michael J. Fox -- by gradually destroying brain cells that produce the chemical messenger dopamine. ... Genetic Research Yields Controversial Parkinsons Drug Target 05 Jan 2006 PharmExec.com, Parkinson’s occurs with the death of brain cells that produce dopamine, a brain chemical that interacts with nerve cells that determine muscle movement ... Mental illnesses develop during teens 05 Jan 2006 Bradenton Herald, Dopamine, a brain chemical that governs pleasure, motivation and interpreting perception, reaches peak production in early to mid-adolescence. ... Binge-drinking blamed for increase in liver cirrhosis across ... 05 Jan 2006 Independent, ...because of genetic factors. * Alcohol boosts the production of dopamine and serotonin in the brain, producing feelings of euphoria. Pennsylvania business news in brief 05 Jan 2006 Centre Daily Times, Parkinson's patients lose brain cells that create dopamine, a chemical vital for motor function. Symptoms include trembling arm, leg and facial muscles. ... What would Plato think of Bush? 05 Jan 2006 The Free Lance-Star, These people enjoy the primal rewards of their mind's reaction to events--adrenalin and dopamine junkies, they are. Lastly are the thinkers. ... Requip(R) (ropinirole HCl) Tablets Significantly Improve Symptoms ... Jan 3, 2006 PR Newswire (press release), Requip is a second-generation dopamine agonist that is available in a variety of strengths for flexible dosing (up to 4 mg/day for RLS patients) to meet ... Variation in dopamine receptor gene is associated with ... Dec 31, 2005 Xagena.it, Cells use the DRD4 gene to make a receptor for a chemical called dopamine, which transmits messages between cells. Dopamine is best ... Hope, happiness and dopamine Dec 23, 2005 Economic Times, Too much anticipation is an enemy of pleasure. Robert Lynd, a British don, said that after a visit to the Taj Mahal at Agra failed ... Study: Dopamine not necessary for pleasure Dec 7, 2005 Science Daily (press release) 21, 2005) -- German scientists say they believe they've discovered a mechanism that may selectively silence the electrical activity of dopamine producing ... ... 'Dopamine made me do it' excuse won't work Dec 8, 2005 Arizona Daily Star, Specifically, the brain chemical dopamine. Dopamine, which ... buy this?". With a little dab of dopamine, it's easy to make bad decisions. ... Dopamine: The joy of shopping Dec 9, 2005 WIS, ...re out looking at new things," says Berns, "The brain says 'aha!' when I see this dress or I see this car and I don't have it and it releases dopamine in the ... Study: Dopamine not necessary for pleasure Dec 7, 2005 Webindia123, Research at the University of Washington suggests the signaling molecule dopamine may not be necessary for the brain to register pleasure. ... Dopamine provides shopper's high Dec 11, 2005 NewKerala.com, ...say US scientists. The surge of excitement from shopping involves dopamine, a chemical associated with pleasure. As shoppers first ... Parkinson's progress at CU health sciences Jan 4, 2006 Cherry Creek News, 30 issue of the Journal of Biological Chemistry.". "Parkinson’s disease is a disorder that occurs when dopamine cells in the brain die or are damaged, making ... Job satisfaction beyond the Hallmark card definition Jan 4, 2006 Globe and Mail, University in Atlanta, says that novel events -- even something as simple as staring at a new piece of art or hearing a new word -- get the dopamine flowing in ... Quit Smoking - Kick The Smoking Habit Once Ang For All Jan 2, 2006 Open PR (press release), Nicotine is the substance responsible for fooling your brain into releasing a "pleasure" chemical called Dopamine. Nicotine receptors ... Addicted to love: Male voles get fix from family Dec 31, 2005 Austin American-Statesman (subscription), ...and even such problems as drug addiction, Florida State University scientists showed that vole faithfulness is the work of a brain chemical called dopamine. ... GSK drug soothes restless legs syndrome Jan 3, 2006 Pharmaceutical Business Review Requip directly activates dopamine receptors in the brain. Although its exact cause is unknown, researchers believe that the underlying ... Studies and Lawsuits Point Accusing Fingers at the Parkinson’s ... Dec 29, 2005 Newsinferno.com, E. Driver-Dunckley, J. Samanta, and M. Stacey published an article entitled “Pathological gambling associated with dopamine agonist therapy in Parkinson’s ... 'The words are yours' Dec 30, 2005 Boston Globe, Alexander Maniatis, cofounder of Dopamine/Amalagate Records, the independent Beverly label that released ''Conductor" last month, recalls the first time he saw ... CU finds how gene may help in Parkinson's fight Dec 28, 2005 Rocky Mountain News, ...and Health Sciences Center performed a detailed analysis of the gene DJ-1. They found that when DJ-1 is functioning properly, it can prevent dopamine cells in ... Role of gene linked to Parkinson's uncovered Dec 29, 2005 NewKerala.com, Parkinsons disease is a disorder that occurs when dopamine cells in the brain die or are damaged, making it increasingly difficult to relay movement messages ... Gene therapy may stall Parkinson's Dec 31, 2005 Contra Costa Times, Parkinson's disease gradually destroys brain cells that produce dopamine, a chemical crucial for the cellular communication that controls muscle movement. ... [FOUNTAIN]Laughing, with or at Jan 2, 2006 International Herald Tribune, ...modern medicine has identified the existence of a "laugh bag." The A10 region in the frontal lobe of the left cerebrum is full of dopamine-releasing nerves. ... Pet friends keep people healthier, happier Jan 4, 2006 Port Townsend Leader, Spending time playing with your dog or cat can elevate serotonin and dopamine levels – nerve transmitters known to have pleasurable and calming properties ... Medicine, politics blend for Green's caring life Jan 4, 2006 Sewickley Herald, Crystal meth is the most addictive drug in the world, even topping heroin, and affects the brain's dopamine receptors so strongly that one-time users can ... Caffeine is everywhere Jan 3, 2006 San Jose Mercury News, Caffeine also increases levels of dopamine, a neurotransmitter that activates the brain's ``pleasure center.'' Although caffeine's effect is much milder ... Winter brings chilling thoughts of my addiction Jan 4, 2006 Globe and Mail, But meth also stimulates the production of excess dopamine in the brain, which causes euphoric sensations -- ones that the brain remembers, and wants you to ... Study IDs Parkinson gene's MO Dec 29, 2005 United Press International ...and co-author of the study. "We show how the normal function of the gene keeps dopamine cells from dying. If the gene is abnormal ... Beware of holiday 'shopping high' Dec 12, 2005 Baltimore Sun, Much of the joy of holiday shopping can be traced to the brain chemical dopamine. Dopamine plays a crucial role in our mental and physical health. ... Evidence Links Cocaine Abuse And Parkinson's Disease Dec 14, 2005 Science Daily (press release) The neurons in the SNpc make the neurotransmitter dopamine, and degeneration of this area and the nigrostriatal system is one of the major hallmarks of PD ... Teens with deletion syndrome confirm role of COMT gene in ... Dec 20, 2005 Xagena.it, The gene version appeared to worsen symptoms of the deletion syndrome by chronically boosting the chemical messenger dopamine to excessive levels in the ... Cocaine abuse linked to Parkinsons disease Dec 13, 2005 Webindia123, The neurons in the SNpc make the neurotransmitter dopamine, and degeneration of this area and the nigrostriatal system is one of the major hallmarks of PD. ... Can’t resist urge to shop? Blame it on brain chemistry Dec 11, 2005 Calcutta Telegraph, Dopamine, a chemical associated with pleasure, is released in waves as shoppers first see a product and then consider buying it. ... Cocaine Abuse Linked to Increased Risk of Parkinson’s Disease ... Dec 20, 2005 Newsinferno.com, ...brain. The neurons in the SNpc make dopamine. Degeneration ... Cocaine is also known to affect dopamine transporter, Smeyne added. This causes ... Lexington firm testing drug to help stuttering Dec 31, 2005 Boston Globe, ...is believed to boost the effects of a brain chemical called GABA, which may indirectly inhibit the release of another chemical, dopamine, which dampens brain ... Huffing and Puffing Jan 2, 2006 Washington Post, ...a person. The antidepressant Wellbutrin has a comparable effect when it increases dopamine and noradrenaline in the brain. The regular ... Failed anti-anxiety drug may help people who stutter Dec 31, 2005 Boston Globe, Pagoclone is believed to boost the effects of a brain chemical called GABA, which may inhibit the release of another chemical, dopamine, which dampens brain ... Joy to the world; it’s season to shop Dec 11, 2005 Fort Wayne Journal Gazette, Much of the joy of holiday shopping can be traced to the brain chemical dopamine. Dopamine is associated with feelings of pleasure ... New drug may help people who stutter Dec 31, 2005 Eyewitness News, That may indirectly inhibit the release of the chemical dopamine. Some studies indicate stutterers have too much dopamine in certain areas of their brains. ... Programs help smokers keep resolution to quit Dec 31, 2005 The Grand Rapids Press, ...level laser light instead of needles, he pinpoints key body points believed to rid the system of nicotine and increase the production of dopamine, a natural ... Special feature: cardiovascular-kidney interactions in health and ... Dec 29, 2005 AJP-Regul Integr Comp Physiology (subscription) ...is modified in hypertension. Recent studies have characterized the interaction between dopamine and ROS. Activation of dopamine1 ... Addicts often turn violent, paranoid Dec 31, 2005 Grand Junction Sentinel, It is a central nervous system stimulant that releases high levels of the neurotransmitter dopamine, enhancing mood and body movement, according to the ... Caught in the Web? Jan 3, 2006 myDNA.com, But Greenfield said he still sees Internet addiction as its own disorder since a physical substance isn't required to release large levels of dopamine into the ... Off The Reel: Bay Area Women Filmmakers Join Forces Jan 2, 2006 Bay Area BusinessWoman News, BAWIFT currently offers members the on-line forum; monthly professional panels featuring notables such as producer Debbie Brubaker (Dopamine, Swing) and ... Research offers Parkinson's hope Dec 29, 2005 Webindia123, We show how the normal function of the gene keeps dopamine cells from dying. If the gene is abnormal, these protective mechanisms cannot be brought into play. ... Caspian's instrumental set says it all Jan 2, 2006 Boston Globe, ...out thrall of ''Crawlspace." The beauty of the band's debut EP, ''You Are the Conductor," which was released this fall by Beverly indie Dopamine Records, was ... When every bet comes up a loser Jan 3, 2006 Barre Montpelier Times Argus, Researchers have shown that many pathological gamblers' brains are lacking in receptors to process the feel-good chemical dopamine, leading them to ever larger ... Messengers of the Brain Jan 1, 2006 About - News & Issues, When they don't, you can get illnesses like Parkinson's, which has a dopamine deficiency; or you may have tetanus, which prevents the release of GABA and can ... Embrace imperfect, ordinary lives Jan 2, 2006 Albany Times Union, Research suggests the shift in how we experience time is also a result of lowering dopamine levels in the brain that happens as we age. ... Moving toward a better life Dec 25, 2005 Milwaukee Journal Sentinel (subscription), In Parkinson's patients, brain cells that make dopamine, a chemical that controls movement, die. To make up for the loss of dopamine ... Love is a drug Dec 5, 2005 Daily Mail - UK, Both involve the messenger chemical dopamine, which stimulates the brain's "reward centre". It is partly because of dopamine that ... Love to Shop? There's A Health Reason for That Dec 10, 2005 WLNS, They say when you see something you like, and don't have it, it releases dopamine in the brain. Dopamine is a neurotransmitter that ... Restless Legs Syndrome Fact Sheet Dec 14, 2005 Community Dispatch (press release) Dopamine agonists such as pergolide mesylate, pramipexole, and ropinirole hydrochloride may be effective in some patients and are less likely to cause ... Neurological Biosensor Developed? Dec 14, 2005 Medgadget.com, Once inside the body, the chips perform several functions. They sense and monitor the release of essential chemicals produced by the brain, including dopamine. ... Neupro Receives Positive Opinion from European CHMP for the ... Dec 15, 2005 PharmaLive.com (press release), ..."Transdermal administration of a dopamine agonist offers a promising option for patients ... Dopamine agonists attempt to compensate for this lack of dopamine. ... Shoes, don't fail me now Dec 14, 2005 Seattle Times, The happiness or mood-lifting is tied to dopamine, a chemical in the brain linked to mental and physical health. Dopamine is released ... Joy of Shopping Explained Dec 8, 2005 ABC News It turns out that cashmere scarf is not the source of your joy after all. It is the pursuit, and a pleasurable little brain chemical called dopamine. ... Altered cells deliver Parkinson's therapy to brain Dec 27, 2005 Reuters.uk, A nerve growth factor called "glial cell line-derived neurotrophic factor" (abbreviated to GDNF) has been shown to protect dopamine-producing neurons, which ... Study: Genetic link to schizophrenia Dec 2, 2005 myDNA.com, PRODH and COMT contributes directly to major symptoms of schizophrenia by upsetting the balance of the brain chemicals glutamate and dopamine, according to a ... METH & DESTRUCTION: From the backwoods to the big city Dec 28, 2005 Kosciusko Star Herald, Meth can disrupt the brain’s dopamine levels for more than 18 hours. By contrast, crack cocaine blocks dopamine, a natural chemical, for 15 minutes. ... New Year's Cold Turkey Quit Smoking Tips Dec 29, 2005 WhyQuit, Although your mind's nicotine induced dopamine/adrenaline intoxication is an alert high, your chemical dependency is every bit as real and permanent as ... Kids tip police to New Haven meth lab; man held Dec 29, 2005 Fort Wayne Journal Gazette, Smoked, injected or inhaled, methamphetamine triggers the brain to rapidly release the chemical dopamine, which gives users energy, suppresses their appetites ... Resolve to Quit Smoking Dec 29, 2005 Newswise (press release) Zyban). Zyban stimulates the release of a feel-good chemical in the brain, called dopamine, to simulate the effect of nicotine. ... Eye cell implants may ease Parkinson's - study Dec 12, 2005 Malaysia Star, ...layer of the eye's retina make levodopa, which Parkinson's patients commonly take in pill form to replace lost production of the neurotransmitter dopamine. ... 'Trojan cells' treat brain diseases from the inside Dec 15, 2005 New Scientist (subscription), Previous studies show that GDNF increases the survival and function of dopamine-producing cells, which are progressively destroyed in Parkinson’s disease. ... HealthWrap: Cocaine link to Parkinson's? Dec 13, 2005 Science Daily (press release) The study found that cocaine alters nerve bodies in a region of the brain that manufactures dopamine and makes them more prone to damage from MPTP, a toxin ... Doctors look to virus for cure Dec 14, 2005 Columbia Daily Tribune, Parkinson’s disease gradually destroys brain cells that produce dopamine, a chemical crucial for the cellular communication that controls muscle movement. ... Progress against Parkinson's Dec 14, 2005 Wisconsin State Journal, Then they injected the cells into the rats' striatum, the part of the brain where the chemical dopamine acts like a lubricant enabling the body's movement. ... No joke, Germans laugh Dec 29, 2005 International Herald Tribune, ...stress and help alleviate depression because laughter spurs the brain to activate pain-reducing endorphins and neurotransmitters known as dopamine that create ... GM cells deliver Parkinson's therapy Dec 27, 2005 ABC Online, A nerve growth factor called "glial cell line-derived neurotrophic factor" (GDNF) has been shown to protect dopamine-producing neurons, which are lost in ... Unraveling Parkinson's disease Dec 25, 2005 Boston Globe, ...bean-size sliver at the base of the brain -- called the substantia nigra -- is crammed with more than half a million neurons that produce dopamine, a messenger ... Meth’s deadly buzz Jan 1, 2006 Standard-Speaker, ...crank and dozens of other names — is energy, the sort of raw, unbridled, jumpy rush that comes from supercharging the brain with a dopamine high similar to a ... ASPARTAME FEEDBACK DIALOGUE Dec 30, 2005 Free Market News Network, This affects the dopamine system of the brain and causes the addiction. Aspartame damages DNA which has been proven in the Trocho Study in l998. ... Mind matters Dec 30, 2005 Waxahachie Daily Light, ...“It’s not something you fight on your own,� she said. “It’sa lack of certain chemicals in the brain: seratonin and dopamine.�. Now we know - love is the drug you can't forget! Dec 6, 2005 News-Medical.net, ...that males only became devoted to females after they had mated, and that bond coincided with a huge release of the feelgood chemical dopamine inside their ... Retail therapy works Dec 9, 2005 myDNA.com, ...of California, Los Angeles, School of Medicine's Ahnanson-Lovelace Brain Mapping Center, told ABC News that increases in the production of dopamine is what ... Health: Shopping High Dec 7, 2005 CBS 3, Now a new study says that shopping can be an addiction for some, triggering the release of a brain chemical called dopamine. Dopamine ... BrainStorm Makes Progress Towards Human Stem Cell Therapy for ... Dec 13, 2005 Genetic Engineering News, ...strategy is based on a unique process for differentiating bone marrow stem cells into neural-like cells capable of secreting dopamine, the substance that is ... Health Study : How Love is as Addictive as a Drug Dec 7, 2005 Daijiworld.com, Called dopamine, the chemical stimulates the brain’s ‘reward centre’ and plays a key role in our desire to repeat good experiences. ... GOOD MORNING LOWCOUNTRY Dec 6, 2005 Charleston Post Courier (subscription), Novel experiences trigger the body's production of dopamine, she said. Dopamine ... Dopamine is one of our most important chemicals. Taken ... Restless Legs Syndrome: Misdiagnosed, Misunderstood Dec 9, 2005 Christian Broadcasting Network, But Thorpy said drugs in a class called "dopamine agonists" have proven very helpful in combating the symptoms and providing relief. ... Nanotech draws support Dec 6, 2005 Daily Free Press (subscription), ...presented a new way to use Haldol, a drug that affects dopamine levels in the brain, on specific cells in only certain regions of the brain. ... Chinese Laundry launches Break Inn the new year Dec 14, 2005 Resident Advisor, ...many a breaks fan. The night will feature residents Bass Kleph, The Impossibles, Dopamine and the Sound Advice DJs. The main room ... Zebrahead live at the Wedgewood Rooms Dec 20, 2005 The Wessex Scene, Most notable were Dopamine, last on the bill before the headliners and reminiscent of old-school emo before, like so many of the other alternative music genres ... Engineered Stem Cells Show Promise For Sneaking Drugs Into The ... Dec 15, 2005 Science Daily (press release) To work effectively, the cells in the striatum require dopamine, a chemical that is produced deep in the brain and that travels up nerve fibers to the striatum ... Gene therapy vs. Parkinson's Dec 14, 2005 Health24.com, UCSF) and Rush University researchers uses the nerve growth factor neurturin to protect and rescue dying brain cells that produce dopamine, the Associated ... Love is in the head, not heart: study Dec 5, 2005 NewKerala.com, The rodents usually form lifelong monogamous pair-bonds with their mating partners, but researchers found that certain dopamine receptors in a specific region ... Monogamy May Be Linked To Chemical Activity Dec 5, 2005 All Headline News The brain chemical, dopamine, which stimulates the brain's reward center, keeps people going back to sources of pleasure, such as good food and drug addictions ... Cocaine use 'is Parkinson's risk' Dec 13, 2005 Monsters and Critics.com, Researchers also found that cocaine disrupted the function of the dopamine transporter in the brain, a protein that removes excess dopamine from the brain. ... Shop 'Til You ... Feel Better Dec 6, 2005 Click 2 Houston.com, ...great bargain. According to a recent NBC report, the chemical that is released during shopping is called dopamine. This chemical ... Shopping for your health Dec 7, 2005 WTNH, It also creates high levels of dopamine in the brain. The dopamine in turn stimulates the pleasure centers of the brain. Scientists ... Rotigotine in Advanced Parkinson's Disease Shows Positive Trial ... Dec 20, 2005 Biotech Intelligence (press release), The patients - roughly four million worldwide - suffer from a lack of dopamine, a messenger substance in the central nervous system, which is responsible for ... | ||
| Dosage Forms | SOLUTION | ||
| Drug_Category | Cardiotonic Agents; Sympathomimetic; ATC:C01CA04 | ||
| Absorption | Dopamine is rapidly absorbed from the small intestine. | ||
| Interactions |
Interactions for Dopamine: Because dopamine is metabolized by monoamine oxidase (MAO), inhibition of this enzyme prolongs and potentiates the effect of dopamine. Patients who have been treated with MAO inhibitors within two to three weeks prior to the administration of dopamine HCl should receive initial doses of dopamine HCl no greater than one-tenth (1/10) of the usual dose. Concurrent administration of low-dose dopamine HCl and diuretic agents may produce an additive or potentiating effect on urine flow. Tricyclic antidepressants may potentiate the cardiovascular effects of adreneric agents. Cardiac effects of dopamine are antagonized by beta-adrenergic blocking agents, such as propranolol and metoprolol. The peripheral vasoconstriction caused by high doses of dopamine HCl is antagonized by alpha-adrenergic blocking agents. Dopamine-induced renal and mesenteric vasodilation is not antagonized by either alpha-or beta-adrenergic blocking agents. Butyrophenones (such as haloperidol) and phenothiazines can suppress the dopaminergic renal and mesenteric vasodilation induced with low dose dopamine infusion. Cyclopropane or halogenated hydrocarbon anesthetics increase cardiac autonomic irritability and may sensitize the myocardium to the action of certain intravenously administered catecholamines, such as dopamine. This interaction appears to be related both to pressor activity and to beta-adrenergic stimulating properties of these catecholamines and may produce ventricular arrhythmias and hypertension. Therefore, EXTREME CAUTION should be exercised when administering dopamine HCl to patients receiving cyclopropane or halogenated hydrocarbon anesthetics. It has been reported that results of studies in animals indicate that dopamine-induced ventricular arrhythmias during anesthesia can be reversed by propranolol. The concomitant use of vasopressors, vasoconstricting agents (such as ergonovine) and some oxytocic drugs may result in severe hypertension. Administration of phenytoin to patients receiving dopamine HCl has been reported to lead to hypotension and bradycardia. It is suggested that in patients receiving dopamine HCl, alternatives to phenytoin should be used if anticonvulsant therapy is needed. | ||
| Toxicity | LD50 oral mice = 1460 mg/kg, LD50 oral rats = 1780 mg/kg. Spasm or closing of eyelids, nausea, vomiting, cardiac arrhythmias, involuntary movements of the body including the face, tongue, arms, hand, head, and upper body; hypotension, haemolytic anaemia, urinary retention, duodenal ulcer, sialorrhea, ataxia, abdominal pain, dry mouth, nightmares, tachypnoea, bruxism, confusion, and insomnia. | ||
| Organisms Affected | Humans and other mammals | ||
| Chemical IUPAC Name | 4-(2-aminoethyl)benzene-1,2-diol | ||
| Chemical Formula | C8H11NO2 | ||
| Molecular Weight | 153.178 g/mol | ||
| Smiles String | C1=CC(=C(C=C1CCN)O)O | ||
| Melting Point | 82.5 °C | ||
| Water Solubility | 1E+006 mg/L | ||
| State | Solid | ||
| LogP/Hphobicity | 0.548 | ||
| Isoelectric Point | 8.93 | ||
| Biotransformation | Biotransformation of dopamine proceeds rapidly to yield the principal excretion products, 3-4-dihydroxy-phenylacetic acid (DOPAC) and 3-methoxy-4-hydroxy-phenylacetic acid (homovanillic acid, HVA). | ||
| Half Life | 2 minutes | ||
| Protein Binding [%] | No information currently available on protein binding. | ||
| RxList Link | RXlist | ||
| Sponsored links | |||
| Drug Reference | http://www.rxlist.com/cgi/generic3/dopamine.htm | ||
| Drug Type | Approved Drug | ||
| Accession No | APRD00085 | ||
| CAS Registry Number | 51-61-6 | ||
| KEGG Compound ID | C03758 | ||
| PubChem ID | SID:2667 | ||
| PharmGKB ID | PA449396 | ||
| SwissProt ID | Not Available | ||
| GenBank ID | Not Available | ||
| Drug ID Number [DIN] | 1914014 |
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