Dobutamine drug data and news

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Heart attack: The silent killer  Mar 3, 2006
...of the blood vessels using x-rays following the injection of a radiopaque substance), Non-Invasive Angiography or Dobutamine-Echocardiography (Ultrasound test ... - CNN-IBN,

Attempts to Recruit Stem Cells for Repair of Acute Myocardial ...  Feb 28, 2006
...was improved by G-CSF plus stem cell factor in that ejection fraction improved to a greater extent when treated rats were exposed to dobutamine compared with ... - Journal of American Medical Association (subscription),

Orion Oyj: Orion group 2005 financial statements  Feb 9, 2006
In this study in about 1,300 patients levosimendan was compared to dobutamine. ... In this study in about 1,300 patients levosimendan was compared to dobutamine. ... - Kauppalehti (press release),

Combined atrial arterial switch operation (double switch) for ...  Feb 14, 2006
...respectively, in the second. Postoperatively, adrenaline, dobutamine, and milrinone infusions were instituted. Figure 1 A, Diagram ... - The Journal of Thoracic and Cardiovascular Surgery

Reply to the Editor  Feb 17, 2006
The inotrope score used in our study, adapted from Wernovsky and associates, 2 was determined by the use of dopamine, dobutamine, milrinone, epinephrine, and ... - The Journal of Thoracic and Cardiovascular Surgery

Physiological role of the 1 - and 2 -isoforms of the Na + -K ...  Feb 14, 2006
Furthermore, their baseline cardiovascular hemodynamics are normal (15). The animals also respond normally to the -adenergic agonist dobutamine. ... - AJP-Regul Integr Comp Physiology (subscription)

Mark Patinkin: In nonfiction, to check the facts, go to the source  Feb 4, 2006
I had a doctor saying "Give me a bolus of debutamine," but it was really a drip, not a bolus. And it should have been spelled "dobutamine.". ... - Providence Journal (subscription),

Orion Oyj: Orion group 2005 financial statements  09 Feb 2006
In this study in about 1,300 patients levosimendan was compared to dobutamine. ... In this study in about 1,300 patients levosimendan was compared to dobutamine. ... - Kauppalehti (press release),

Go to the source to check the facts  Feb 6, 2006
I had a doctor saying, "Give me a bolus of debutamine," but it was really a drip, not a bolus. And it should have been spelled "dobutamine.". ... - Scripps Howard News Service,

Assumed oxygen consumption in the determination of cardiac output ...  Jan 23, 2006
Penny DJ, Sano T, Smolich JJ. Increased systemic oxygen consumption offsets improved oxygen delivery during dobutamine infusion in newborn lambs. ... - The Journal of Thoracic and Cardiovascular Surgery

Abbott heart drug fails to better dobutamine  Nov 18, 2005
Abbott's drug levosimendan failed to reduce mortality significantly more than the industry standard dobutamine in a trial conducted in 1,327 patients with ... - Pharmaceutical Business Review

Stress Echo Tests Shown To Predict Cardiac Death, Illness In ...  Nov 26, 2005
Investigators concluded that the test, known as dobutamine stress echocardiography, provided valuable information that could help doctors predict future fatal ... - Science Daily (press release)

Wyeth’s President, Research & Development, Wyeth Pharmaceuticals ...  Dec 9, 2005
Laboratories, Dr. Ruffolo played a significant role in the discovery and/or development of a number of marketed products, including Dobutamine (Dobutrex) for ... - PharmaLive.com (press release),

Orion Oyj: Abbott reports levosimendan (simdax®) results from ...  Nov 16, 2005
...levosimendan (Simdax®) results from large mortality trial in patients with acute decompensated heart failure – Study Supports Trend Over Dobutamine but Does ... - Kauppalehti (press release),

Abbott Reports Levosimendan (Simdax(R)) Results From Large ...  Nov 16, 2005
Simdax®, outside the United States) resulted in statistically non-significant but consistently lower mortality compared with dobutamine through six months of ... - Yahoo! News (press release)

Abbott Reports Levosimendan (Simdax(R)) Results From Large ...  Nov 16, 2005
...- Study Supports Trend Over Dobutamine But Does Not Meet 25 Percent Target for Mortality Reduction - DALLAS, Nov. 16 /PRNewswire ... - PR Newswire (press release),

Abbott Heart Failure Drug Misses Goal  Nov 16, 2005
The study, SURVIVE, compared Simdax, also known as levosimendan, with an older treatment called dobutamine. The goal of the trial ... - Forbes

Abbott's Heart Drug Fails to Prolong Life in Study (Update3)  Nov 16, 2005
26.1 percent of those getting Simdax died after six months, compared with 27.9 percent of those on the generic heart- failure drug dobutamine, an insignificant ... - Bloomberg

Abbott's Heart Drug Fails to Prolong Life in Study (Update1)  Nov 16, 2005
Instead, 26.1 percent getting Simdax died after six months, compared with 27.9 percent on dobutamine, a difference that wasn't significant. ... - Bloomberg

Stress test important for diabetic women  Nov 15, 2005
LOUIS, Nov. 15 (UPI) -- St. Louis University School of Medicine scientists are recommending diabetic women undergo dobutamine echocardiography stress testing. ... - Science Daily (press release)

Stress test important for diabetic women  Nov 15, 2005
Louis University School of Medicine scientists are recommending diabetic women undergo dobutamine echocardiography stress testing. ... - Monsters and Critics.com,

Abbott heart drug shows scant survival benefit  Nov 16, 2005
The drug showed some survival benefit after five days and also after one month in the 1,327 patient study comparing it with dobutamine, which was also ... - Reuters AlertNet,

Open Questions For Heart Failure Drugs  Nov 14, 2005
But for about half of patients, these drugs are not enough. Often, doctors turn to older medicines like dobutamine and milrinone to try and improve symptoms. ... - Forbes

Orion says Simdax drug fails to meet reduction in mortality target ...  Nov 16, 2005
...'It showed that levosimendan/Simdax resulted in statistically non-significant but consistently lower mortality compared with dobutamine through six months of ... - Forbes

Abbott heart drug shows scant benefit-study  Nov 16, 2005
...on Wednesday. The drug showed early benefit in reducing death in the 1,327-patient study comparing Simdax to dobutamine. But Abbott's ... - Reuters

Abbott heart drug shows scant survival benefit  Nov 16, 2005
...on Wednesday. The drug showed early benefit in reducing deaths in the 1,327-patient study comparing Simdax to dobutamine. But Abbott's ... - ABC News

Under study: Drug helps weakest hearts  Nov 16, 2005
Heart Association. The new study of 1,327 patients compared those taking the drug with those on an older drug called dobutamine. The ... - USA Today

New heart drug helps patients in crisis  Nov 17, 2005
Southwestern Medical Center at Dallas reported to the American Heart Association this week that in a trial of levosimendan against the drug dobutamine, the new ... - United Press International

Orion Oyj: Orion group interim report 1-9/2005  Nov 7, 2005
Approximately 1,300 patients with ADHF were treated with either levosimendan or the standard treatment dobutamine, the follow-up period being 180 days. ... - Kauppalehti (press release),

Association of Ischemia on Stress 99m Tc-Tetrofosmin Myocardial ...  Oct 4, 2005
Methods: We studied 297 patients with diabetes mellitus and known or suspected CAD by exercise or dobutamine stress 99m Tc-tetrofosmin myocardial perfusion ... - Journal of Nuclear Medicine

Adrenal Insufficiency in Septic Shock  Sep 30, 2005
...of shock was classified as fluid-responsive, fluid-refractory (shock that was reversed by 60 mL/kg fluid resuscitation and dopamine or dobutamine 10 µg/kg per ... - AAP Grand Rounds (subscription)

Ebstein's Anomaly  Sep 24, 2005
...regurgitation were found. Initially, the patient had a response to fluid restriction and intravenous furosemide and dobutamine. On the ... - New England Journal of Medicine (subscription),

Heart device grants new lease on life  Sep 12, 2005
She was hospitalized numerous times, and got to a point where she required twice-weekly intravenous doses of dobutamine, a medication given to prevent the ... - New Brunswick Home News Tribune,

Risk of Death With Nesiritide  Aug 23, 2005
2 The VMAC study was considered the "real world" study and there was significantly greater concomitant use of dobutamine in the nesiritide group compared with ... - Journal of American Medical Association (subscription),

Risk of Death With Nesiritide—Reply  Aug 23, 2005
However, our analysis accounts for differences in the use of dobutamine as a concomitant therapy within VMAC, where its use was not a significant predictor of ... - Journal of American Medical Association (subscription),

Myocardial Protection in Diabetics With Left Main Stem Disease ...  Aug 12, 2005
Inotropic support was defined as low dose when enoximone or dobutamine were administered at dosage lower than 5 g/kg/min. Medium ... - RedNova.com,

Risk of Death With Nesiritide  Aug 23, 2005
In a recent study, 2 risk factor and propensity score–adjusted in-hospital mortality odds ratios (ORs) for dobutamine relative to nesiritide and ... - Journal of American Medical Association (subscription),

Perioperative internal thoracic artery steal syndrome after ...  Aug 5, 2005
At 3 months’ follow-up, dobutamine stress echocardiography showed no inducible wall-motion abnormality and increased diastolic ITA flow, indicating a normal ... - The Journal of Thoracic and Cardiovascular Surgery

Noninvasive Diagnosis of Coronary Artery Disease in Patients With ...  Jul 9, 2005
OBJECTIVE - The aim of this study was to assess the accuracy of real-time myocardial contrast perfusion imaging (MCPI) during dobutamine stress in the ... - RedNova.com

Vasodilators first choice for some heart patients  Jul 9, 2005
In comparisons of patients treated intravenously with nitroglycerin, nesiritide, dobutamine or milrinone, there was a lower in-hospital mortality rate for ... - I-Newswire.com (press release)

Al Hayat adds new facilities  Jul 10, 2005
...and lungs with all the modern facilities, including coronary angiogram and ICCU, has introduced new facilities: Exercise stress echo, dobutamine stress echo ... - Times of Oman

Chemical 'Band-aid' Prevents Heart Failure In Mice With Muscular ...  Jul 18, 2005
To examine the effects of P188 on mdx hearts under stress, UM researchers gave the mice a drug called dobutamine to make the heart work harder and faster for ... - Science Daily (press release)

New Data on Heart Failure Drugs  Jul 10, 2005
...patients. Specifically, they looked at patients given one of four drugs including nitroglycerin, nesiritide, milrinone or dobutamine. ... - Ivanhoe

Poloxamer Strengthens Dystrophic Hearts in Mice  Jul 18, 2005
Pretreatment of mdx mice with poloxamer improved the attenuated response to dobutamine infusion and also protected against dobutamine-induced acute heart ... - Medscape (subscription)

FDA MedWatch - Natrecor (nesiritide): Recommendations of Expert ...  Jul 18, 2005
...therapy for patients not sufficiently responsive to another IV vasoactive therapy, or as add-on therapy in patients refractory to dobutamine or dopamine. ... - PharmaLive.com (press release)

Vasodilator Drugs Fight Advanced Heart Failure  Jul 6, 2005
...nitroglycerin and nesiritide had lower in-hospital death rates than those who received either of two positive inotrope drugs, dobutamine and milrinone. ... - Forbes

Value of absence of a transient myocardial perfusion defect during ...  Jul 15, 2005
Six patients received dipyridamole infusion of 0.56 mg/kg over 4 min. Two patients received dobutamine infusion at 5, 10, 20, 30, and 40 mg/kg/min. ... - HeartZine

Left ventricular restoration for ischemic cardiomyopathy and ...  Jul 12, 2005
...halt, hemodynamic parameters showed no deterioration, and left ventricular ejection fraction and cardiac index improved with the increasing dose of dobutamine. ... - The Journal of Thoracic and Cardiovascular Surgery

Animal studies indicate that dobutamine may be ineffective if the patient has recently received a b-blocking drug. In such a case, the peripheral vascular resistance may increase.

Preliminary studies indicate that the concomitant use of dobutamine and nitroprusside results in a higher cardiac output and, usually, a lower pulmonary wedge pressure than when either drug is used alone.

There was no evidence of drug interactions in clinical studies in which dobutamine was administered concurrently with other drugs, including digitalis preparations, furosemide, spironolactone, lidocaine, glyceryl trinitrate, isosorbide dinitrate, morphine, atropine, heparin, protamine, potassium chloride, folic acid, and acetaminophen.