|
![]() |
|
|
Desmopressin
drug data and news
Desmopressin drug data, resources, and news articles (when available). Onconews.org provides news on cancer research. This section, which includes profiles on medicines that may or not be cancer-related is in beta form. If things run smoothly we will be releasing a new format late in the summer of 2006.
|
| Generic name | Desmopressin | ||
| Brand Names/Synonyms | DESMOPRESSIN; Desmopresina [INN-Spanish]; Desmopressine [INN-French]; Desmopressinum [INN-Latin]; 1-Deamino-8-D-arginine vasopressin; 1-Desamino-8-D-arginine vasopressin; 1-Desamino-8-d-arginine-vasopressin; Desamino-8-D-arginine vasopressin, l-; Concentraid; DDAVP; Stimate | ||
| Indication | For the management of primary nocturnal enuresis and indicated as antidiuretic replacement therapy in the management of central diabetes insipidus and for the management of the temporary polyuria and polydipsia following head trauma or surgery in the pituitary | ||
| Sponsored links | Description | Desmopressin is a chemical that is similar to a hormone found naturally in your body. It increases urine concentration and decreases urine production. Desmopressin is used to prevent and control excessive thirst, urination, and dehydration caused by injury, surgery, and certain medical conditions, allowing you to sleep through the night without awakening to urinate. It is also used to treat specific types of diabetes insipidus and conditions after head injury or pituitary surgery. | |
| Pharmacology | Desmopressin is a synthetic analogue of the natural pituitary hormone 8-arginine vasopressin (ADH), an antidiuretic hormone affecting renal water conservation. Desmopressin is indicated as antidiuretic replacement therapy in the management of central diabetes insipidus and for the management of the temporary polyuria and polydipsia following head trauma or surgery in the pituitary region and is also indicated for the management of primary nocturnal enuresis. | ||
| Mechanism Of Action | Desmopressin emulates the actions of the natural pituitary hormone 8-arginine vasopressin (ADH). | ||
| Desmopressin News (When available) |
Federal Court Affirms Barr Summary Judgment in DDAVP(R) Patent ... Feb 15, 2006 Sanofi expects Acomplia launch in 06; profits up Feb 24, 2006 ZLB Behring Announces Availability of Humate-P(R) with Smaller ... Feb 15, 2006 Barr Reports Second Quarter Fiscal 2006 GAAP Earnings of $0.88 Per ... Feb 7, 2006 Barr Should Get Earnings Boost From Key Drugs Feb 6, 2006 Barr reports strong quarterly earnings Feb 8, 2006 Barr prevails in DDAVP patent appeal Feb 15, 2006 Head-to-Head Study Shows EUFLEXXA(TM) Has Greater Tolerability ... Feb 13, 2006 Teva Announces Approval of Desmopressin Acetate Tablets Jan 29, 2006 FDA approval for Teva's desmopressin acetate tablets Jan 29, 2006 Desmopressin improves nighttime urination in men Jan 17, 2006 Ranbaxy to sell Swiss Ferring's Desmopressin in India Jan 10, 2006 Barr reports strong quarterly earnings Feb 8, 2006 Barr Reports Second Quarter Fiscal 2006 GAAP Earnings of $0.88 Per ... Feb 7, 2006 Drug improves nighttime urination in men Jan 17, 2006 Barr Should Get Earnings Boost From Key Drugs Feb 6, 2006 Ranbaxy signs mktg deal with Ferring Intl Jan 10, 2006 Ranbaxy gets into mktg agreement with Swiss Company Jan 10, 2006 Ranbaxy to co-market Ferrings` urology drug Jan 10, 2006 RANBAXY: Ranbaxy To Co-Market Ferring's Urology Drug In India ... Jan 11, 2006 Ranbaxy ties up with Swiss Co to sell its drug in India Jan 10, 2006 Ranbaxy enters into co-marketing agreement with Swizz co Jan 10, 2006 Ranbaxy enters into agreement with Ferring International ... Jan 10, 2006 Ranbaxy signs co-marketing pact with Ferring 1/10/2006 1:49:45 PM ... Jan 10, 2006 Ranbaxy in co-marketing agreement with Ferring of Switzerland Jan 10, 2006 Sensex slides 138 points Jan 10, 2006 Indian shares fall ahead of Reliance Jan 10, 2006 Wrap up: Sensex slumps 138 points Jan 10, 2006 Ranbaxy Year 2005 Global Sales at USD 1178 Mn Jan 18, 2006 FAMILY DOCTOR: New drugs can help reduce so many nighttime trips ... Dec 7, 2005 Ferring Pharmaceuticals Announces Launch of EUFLEXXA for ... Nov 14, 2005 Leading Urology Experts Call For Better Recognition And Treatment ... Sep 10, 2005 No-Transfusion Liver Graft in Surgical Tour de Force Sep 26, 2005 Positive approach to dealing with bedwetting Sep 12, 2005 Barr Reports GAAP Earnings of $2.03 Per Share for Fiscal 2005 and ... 08 Sep 2005 Barr Reports GAAP Earnings of $2.03 Per Share for Fiscal 2005 and ... 08 Sep 2005 Leading Urology Experts Call For Better Recognition And Treatment ... Sep 4, 2005 Major cause of sleep loss to be discussed at International ... Aug 29, 2005 Changes to drug ads may be on the horizon Aug 14, 2005 First-Time Generic Approvals: Rocephin, Sinemet, DDAVP Jul 8, 2005 Growth lifts B&L revenue forecast Jul 28, 2005 NJ business briefs Jul 6, 2005 | ||
| Dosage Forms | TABLET | ||
| Drug_Category | Renal Agents; Hemostatics (20:12.16); Pituitary (68:28.00); ATC:H01BA02 | ||
| Absorption | Not Available | ||
| Interactions | Interactions for Desmopressin: Although the pressor activity of Desmopressin is very low compared to its antidiuretic activity, large doses of Desmopressin Tablets should be used with other pressor agents only with careful patient monitoring. | ||
| Toxicity | Not Available | ||
| Organisms Affected | Humans and other mammals | ||
| Chemical IUPAC Name | 1-[[13-benzyl-10-(2-carbamoylethyl)-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicos-4-yl]carbonyl]-N-[1-(carbamoylmethylcarbamoyl)-4-guanidino-butyl]-pyrrolidine-2-carboxamide | ||
| Chemical Formula | C46H64N14O12S2 | ||
| Molecular Weight | 1069.22 g/mol | ||
| Smiles String | C1CC(N(C1)C(=O)C2CSSCCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)C(=O)NC(CCCN=C(N)N)C(=O)NCC(=O)N | ||
| Melting Point | Not Available | ||
| Water Solubility | Not Available | ||
| State | Solid | ||
| LogP/Hphobicity | -3.715 | ||
| Isoelectric Point | Not Available | ||
| Biotransformation | Not Available | ||
| Half Life | 1.5-2.5 hours | ||
| Protein Binding [%] | 50% | ||
| RxList Link | RXlist | ||
| Sponsored links | |||
| Drug Reference |
http://www.drugs.com/cons/Desmopressin.html http://www.rxlist.com/cgi/generic3/desmoprt.htm | ||
| Drug Type | Approved Drug | ||
| Accession No | BIOD00112 | ||
| CAS Registry Number | 16679-58-6 | ||
| KEGG Compound ID | Not Available | ||
| PubChem ID | SID:170515 | ||
| PharmGKB ID | Not Available | ||
| SwissProt ID | Not Available | ||
| GenBank ID | Not Available | ||
| Drug ID Number [DIN] | 2257718 |
|
Home | About | Cancers | Treatment | Medications Copyright onconews.org 2005. All Rights Reserved. |