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Cycrimine
drug data and news
Cycrimine drug data, resources, and news articles (when available). Onconews.org provides news on cancer research. This section, which includes profiles on medicines that may or not be cancer-related is in beta form. If things run smoothly we will be releasing a new format late in the summer of 2006.
| Generic name |
Cycrimine
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| Brand Names/Synonyms |
Cycrimine; H2O; Pagitane; Water |
| Indication |
For treatment and management of Parkinson's disease |
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Description |
Not Available |
| Pharmacology |
Cycrimine is a central anticholenergic used in the treatment of the symptoms of Parkinson's disease. It is a drug used to reduce levels of acetylcholine. Acetylcholine is usually in balance with dopamine neurotransmitters, however lower levels of dopamine are present in the brain of patients suffering from Parkinson's disease. By lowering levels of acetylcholine, it is thought that this balance may be restored. |
| Mechanism Of Action |
Cycrimine binds the muscarinic acetylcholine receptor M1, effectively inhibiting acetylcholine. This decrease in acetylcholine restores the normal dopamine-acetylcholine balance and relieves the symptoms of Parkinson's disease. |
Cycrimine News
(When available) |
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| Dosage Forms |
TABLET |
| Drug_Category |
Antiparkinson Agents; Antidyskinetics; ATC:N04AA |
| Absorption |
Not Available |
| Interactions |
Not Available |
| Toxicity |
Not Available |
| Organisms Affected |
Humans and other mammals |
| Chemical IUPAC Name |
1-cyclopentyl-1-phenyl-3-(1-piperidyl)propan-1-ol |
| Chemical Formula |
C19H29NO |
| Molecular Weight |
287.44 g/mol |
| Smiles String |
C1CCN(CC1)CCC(C2CCCC2)(C3=CC=CC=C3)O |
| Melting Point |
Not Available |
| Water Solubility |
Not Available |
| State |
Solid |
| LogP/Hphobicity |
4.37 |
| Isoelectric Point |
Not Available |
| Biotransformation |
Not Available |
| Half Life |
Not Available |
| Protein Binding [%] |
14-21% |
| RxList Link |
Not Available>RXlist |
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| Drug Reference |
Not Available |
| Drug Type |
Approved Drug |
| Accession No |
APRD00731 |
| CAS Registry Number |
77-39-4 |
| KEGG Compound ID |
Not Available |
| PubChem ID |
SID:301021 |
| PharmGKB ID |
Not Available |
| SwissProt ID |
Not Available |
| GenBank ID |
Not Available |
| Drug ID Number [DIN] |
Not Available
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