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Crotamiton
drug data and news
Crotamiton drug data, resources, and news articles (when available). Onconews.org provides news on cancer research. This section, which includes profiles on medicines that may or not be cancer-related is in beta form. If things run smoothly we will be releasing a new format late in the summer of 2006.
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| Generic name | Crotamiton | ||
| Brand Names/Synonyms | Crotaglin; Crotalgin; Crotamitex; Crotamiton; Crotamitone; Crotan; Eurasil; Eurax; Eurax Cream; Eurax Lotion; Euraxil; Veteusan | ||
| Indication | For eradication of scabies (Sarcoptes scabiei) and for symptomatic treatment of pruritic skin. | ||
| Sponsored links | Description | Not Available | |
| Pharmacology | Crotamiton is usually used to treat pruritis (itching of the skin) caused by scabies or sunburn. Crotamiton relieves itching by producing what is called a counter-irritation. As crotamiton evaporates from the skin, it produces a cooling effect. This cooling effect helps to divert your body's attention away from the itching. Due to this cooling effect it is also effective for the relief of sunburn. The drug is also believed to kill scabies through an unknown mechanism. | ||
| Mechanism Of Action | Crotamiton relieves itching by producing what is called a counter-irritation. As crotamiton evaporates from the skin, it produces a cooling effect. This cooling effect helps to divert your body's attention away from the itching. | ||
| Crotamiton News (When available) |
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| Dosage Forms | CREAM | ||
| Drug_Category | Antiparasitics; Scabicides; Antipruritics; Scabicides; ATC:D04A; ATC:P03AX | ||
| Absorption | Not Available | ||
| Interactions |
Interactions for Crotamiton: None known. | ||
| Toxicity | Not Available | ||
| Organisms Affected | Humans and other mammals | ||
| Chemical IUPAC Name | N-ethyl-N-(2-methylphenyl)-but-2-enamide | ||
| Chemical Formula | C13H17NO | ||
| Molecular Weight | 203.28 g/mol | ||
| Smiles String | CCN(C1=CC=CC=C1C)C(=O)C=CC | ||
| Melting Point | < 25 °C | ||
| Water Solubility | Not Available | ||
| State | yellowish oil | ||
| LogP/Hphobicity | 2.688 | ||
| Isoelectric Point | Not Available | ||
| Biotransformation | Not Available | ||
| Half Life | Not Available | ||
| Protein Binding [%] | Not Available | ||
| RxList Link | RXlist | ||
| Sponsored links | |||
| Drug Reference |
http://www.drugs.com/cons/Crotamiton.html http://www.rxlist.com/cgi/generic3/crotamiton.htm | ||
| Drug Type | Approved Drug | ||
| Accession No | APRD00211 | ||
| CAS Registry Number | 483-63-6 | ||
| KEGG Compound ID | C12818 | ||
| PubChem ID | SID:583207 | ||
| PharmGKB ID | PA449142 | ||
| SwissProt ID | Not Available | ||
| GenBank ID | Not Available | ||
| Drug ID Number [DIN] | 623377 |
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