Chlorpheniramine drug data and news

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Long-term risks of prednisone  06 Mar 2006
Antihistamines such as diphenhydramine (Benadryl) or chlorpheniramine (Alka-Seltzer Plus Flu tablets) normally make people drowsy. ... - Los Angeles Times,

Spurious drugs banned  Mar 1, 2006
...feasible for human use include, Phenyton Sodium tab batch no QC-034 manufactured by M/s Kare Lab Pvt Ltd Goa expiray date 12/2007, Chlorpheniramine Maleate tab ... - GreaterKashmir.com (press release),

FDA Joins Investigation of Infants’ Deaths Believed to Have Been ...  Feb 26, 2006
The drugs detected were ephedrine, pseudoephedrine, dextromethorphan, diphenhydramine, chlorpheniramine, brompheniramine, ethanol, carbinoxamine, levorphanol ... - Newsinferno.com,

HUGIN NEWS/UCB Receives EMEA Positive Opinion and FDA Approvable ...  Feb 2, 2006
UCB key products are Keppra® (levetiracetam), Zyrtec®* (cetirizine HCl), Tussionex® CIII (hydrocodone polistirex/chlorpheniramine polistirex), and Equasym(TM ... - FinanzNachrichten.de,

Sniffing? Sneezing? Think twice before medicating  Feb 3, 2006
...with a cough needs, according to Dr. Richard D. Irwin, is a first-generation antihistamine such as diphenhydramine, chlorpheniramine and brompheniramine with a ... - Lowell Sun,

Coping with coughing  Feb 15, 2006
Those older histamines include diphenhydramine, the active ingredient in Benadryl, and chlorpheniramine maleate, the active ingredient in Chlor-Trimeton. ... - South Bend Tribune,

Need help surfing cold and flu medicines?  Feb 1, 2006
Cold and allergy remedies generally include antihistamines (such as chlorpheniramine, brompheniramine or diphenhydramine) to reduce the drips and the sneezes ... - South Bend Tribune,

Epilepsy - UCB Receives EMEA Positive Opinion And FDA Approvable ...  Feb 5, 2006
UCB key products are Keppra® (levetiracetam), Zyrtec®* (cetirizine HCl), Tussionex® CIII (hydrocodone polistirex/chlorpheniramine polistirex), and Equasym(TM ... - Medical News Today (press release),

Sniffing? Sneezing? Think twice before medicating  Feb 3, 2006
...with a cough needs, according to Dr. Richard D. Irwin, is a first-generation antihistamine such as diphenhydramine, chlorpheniramine and brompheniramine with a ... - Lowell Sun,

New Cough Medicine Guidelines  Jan 29, 2006
For coughs tied to the common cold, consider older types of antihistamines -- such as diphenhydramine (found in Benadryl), chlorpheniramine (found in Chlor ... - Charlotte Observer,

No evidence cough syrups work, panel says  Jan 25, 2006
...telephone interview. The older-generation antihistamines that work against cough include chlorpheniramine, he said. Newer, brand ... - Daily Nation (subscription),

Need help surfing cold and flu medicines?  Feb 1, 2006
Cold and allergy remedies generally include antihistamines (such as chlorpheniramine, brompheniramine or diphenhydramine) to reduce the drips and the sneezes ... - South Bend Tribune,

No evidence cough syrups work  Jan 9, 2006
...children, he said. The older-generation antihistamines that work against cough include chlorpheniramine, he said. Newer, brand-name ... - Australian,

Doctors critical of cough syrups  Jan 10, 2006
...antihistamine with a decongestant. Antihistamines that work against cough include chlorpheniramine and diphenhydramine. "There is no ... - Seattle Times,

Spoonful of cold reality  Jan 10, 2006
They include the diphenhydramine in Benadryl, the brompheniramine in Dimetapp, the chlorpheniramine in Chlor-Trimeton, and many other products by the same over ... - Chicago Tribune,

Some Cough Medicines May Hurt, Not Help  Jan 14, 2006
...to children. The older-generation antihistamines that work against cough include chlorpheniramine, Dicpinigaitis said. Newer, brand ... - Los Angeles Times,

In The News: Next Time, Try Soup  Jan 14, 2006
Or try the older-generation antihistamine chlorpheniramine combined with the decongestant pseudoephedrine; they treat the runny nose and nasal congestion that ... - Newsweek

Panel Sees Over-the-Counter Cough Medicines as Useless  Jan 11, 2006
According to the new guidelines, older-generation OTC decongestants and antihistamines such as chlorpheniramine will work best for adults, because they stop ... - Newsinferno.com,

Children Remain Highly Vulnerable to Potentially Deadly Medication ...  Jan 13, 2006
The drugs detected were ephedrine, pseudoephedrine, dextromethorphan, diphenhydramine, chlorpheniramine, brompheniramine, ethanol, carbinoxamine, levorphanol ... - Newsinferno.com,

New guidelines say which drugs really kill a cough  Jan 19, 2006
Newer, not better. Brompheniramine, chlorpheniramine, and diphenhydramine are acceptable antihistamines for ordinary coughs. Newer ... - U.S. News & World Report

Updated Guidelines For Treating Coughs  Jan 24, 2006
...naproxen (sold under several brand names, including Aleve) or older antihistamines, such as diphenhydramine (found in Benadryl), chlorpheniramine (found in ... - Hartford Courant,

Non-prescription cough medicine won't help that cough  Jan 9, 2006
Dicpinigaitis advises the use of the older-generation antihistamines that work against coughs which include chlorpheniramine, newer, brand-name antihistamines ... - News-Medical.net,

Histamine blockers fight allergy symptoms  Dec 4, 2005
...products, while bearing different brand names, contain similar active ingredients such as Brompheniramine maleate (Dimetapp), Chlorpheniramine maleate (Chlor ... - Daytona Beach News-Journal,

You may not be able to find your favorite decongestant  Dec 6, 2005
In the drug realm, antihistamines such as diphenhydramine (Benadryl), chlorpheniramine (Chlor-Trimeton), cetirizine (Zyrtec), and loratadine (Claritin) can ... - DetNews.com,

Infants Dying as a Result of Overdosing with Over-the-Counter Cold ...  Nov 17, 2005
The drugs detected were ephedrine, pseudoephedrine, dextromethorphan, diphenhydramine, chlorpheniramine, brompheniramine, ethanol, carbinoxamine, levorphanol ... - Newsinferno.com,

Mother explains horrors of local OTC drug abuse  Nov 9, 2005
C (CCC), a nickname for the cough medicine Coricidin HBP Cold & Cough, the most popular brand of dextromethorphan (DXM) and chlorpheniramine maleate that is ... - Examiner - Allentown,

No Pregnant Pause  Oct 10, 2005
With antihistamines, chlorpheniramine (Chlor-Trimetron) use has decreased, while mid-pregnancy use of diphenhydramine (Benadryl) has grown over the last 30 ... - Washington Post,

DSHS investigating 2 deaths  Sep 22, 2005
...who had lived at Frances Haddon Morgan Center for 20 years, died after ingesting 5-½ times the normal dose of the antihistamine chlorpheniramine, which can ... - Seattle Times,

UCB's Anti-Epileptic Keppra(R) Meets Primary End-Point in ...  Sep 15, 2005
...key products in the US are Keppra® (levetiracetam), Zyrtec®(1) (cetirizine HCl), Tussionex® CIII (hydrocodone polistirex/chlorpheniramine polistirex), and ... - Yahoo! News (press release)

UCB's Anti-Epileptic Keppra(R) Meets Primary End-Point in ...  Sep 15, 2005
...products in the US are Keppra(R) (levetiracetam), Zyrtec(R)(1) (cetirizine HCl), Tussionex(R) CIII (hydrocodone polistirex/chlorpheniramine polistirex), and ... - PR Newswire (press release),

'Mad Max' and cough syrup link explored  Aug 27, 2005
...high-inducing element - DXM - it contains. In addition to DXM, Coricidin also contains chlorpheniramine maleate. This is a class of ... - Lynchburg News and Advance,

Pilot's high drug dose cited in probe of crash  Jul 10, 2005
Toxicology tests found more than 10 times the maximum over-the-counter dose of chlorpheniramine in Lowenstein's system, according to a National Transportation ... - Miami Herald

Certolizumab pegol, positive results in two Phase III Crohn'™s ...  Jul 26, 2005
...key products in the US are Keppra® (levetiracetam), Zyrtec®' (cetirizine HCl), Tussionex® CIII (hydrocodone polistirex/chlorpheniramine polistirex), and ... - Medical News Today (press release)

Sedative likely impaired pilot in fatal 2003 plane crash  Jul 8, 2005
Toxicology tests found more than 10 times the typical, maximum over-the-counter dose of chlorpheniramine, a sedating antihistamine, in Lowenstein's system, the ... - Fort Lauderdale Sun Sentinel

Certolizumab Pegol Demonstrates Positive Results in Two Phase III ...  Jul 27, 2005
...products in the US are Keppra(R) (levetiracetam), Zyrtec(R)(+) (cetirizine HCl), Tussionex(R) CIII (hydrocodone polistirex/chlorpheniramine polistirex), and ... - PharmaLive.com (press release)

Free For All  Jul 21, 2005
...human being. Each 5ml (about one tea spoonful) contains 10 mg Codeine Phosphate IP and 4mg of Chlorpheniramine Maleate. A person ... - Independent-Bangladesh

Over-the-Counter Medicine Cited In Fatal Crash  Jul 13, 2005
..."It is probable that the pilot's performance and judgment were substantially impaired by his very high blood level of chlorpheniramine," the NTSB said. ... - AVweb <**results**>

FAA: Boca Raton pilot impaired by sinus meds  11 Jul 2005
Toxicology tests found more than 10 times the maximum over-the-counter dose of chlorpheniramine in Lowenstein’s system, according to a National ... - Boca Raton News

FDA Approves UCB's Keppra(R) for Use in Childhood Epilepsy  Jun 24, 2005
...key products in the US are Keppra® (levetiracetam), Zyrtec®† (cetirizine HCl), Tussionex® CIII (hydrocodone polistirex/chlorpheniramine polistirex), and ... - ArriveNet (press release)

Allergy medications: Know your options  Jun 25, 2005
Pills, liquids. Over-the-counter oral antihistamines include diphenhydramine (Benadryl), chlorpheniramine (Chlor-Trimeton) and clemastine (Tavist). ... - MayoClinic.com

Substrate of CYP2D6 (minor), 3A4 (major); Inhibits CYP2D6 (weak).

Increased toxicity (CNS depression): CNS depressants, MAO inhibitors, tricyclic antidepressants, phenothiazines.

CYP3A4 inhibitors: May increase the levels/effects of chlorpheniramine. Example inhibitors include azole antifungals, ciprofloxacin, clarithromycin, diclofenac, doxycycline, erythromycin, imatinib, isoniazid, nefazodone, nicardipine, propofol, protease inhibitors, quinidine, and verapamil.