Budesonide drug data and news

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Oxaliplatin Safely Stopped with FOLFOX Regimen for Colorectal ...  Feb 21, 2006
NEW YORK FEB 20, 2006 (Reuters Health) - Treatment with oxaliplatin, a key component of the leucovorin/fluorouracil regimen (FOLFOX) used for metastatic ... - Cancerpage.com,

Xaliproden Reduces Occurrence Of Severe Peripheral Sensory ...  Feb 23, 2006
...compound xaliproden reduced the risk of occurrence of grade 3 peripheral sensory neuropathy (PSN) by 39% in patients treated with oxaliplatin injection-based ... - Medical News Today (press release),

Patients Of UK's Second Biggest Killer To Gain Access To ...  Feb 28, 2006
...published their Final Appraisal Determination (FAD), which advocates the use of the potentially life-saving treatment Eloxatin (oxaliplatin) in combination ... - Medical News Today (press release),

Province not paying for pricey cancer drug  Feb 19, 2006
Alberta is one of three provinces that doesn't fund the drug oxaliplatin, considered an effective therapy for advanced colorectal cancer, because of a patent ... - Edmonton Journal,

Recruitment Temporarily Suspended In An International Phase III ...  Feb 20, 2006
...centers from 33 countries) randomizing high-risk stage II and stage III patients with colon cancer to FOLFOX-4 (infused/bolus 5-FU/LV + oxaliplatin), FOLFOX-4 ... - Medical News Today (press release),

Pro-Pharmaceuticals to Present Abstract & Poster at Mass ...  Mar 2, 2006
...to 800 patients in 60 centers and consist of four arms: Irinotecan, leucovorin and 5-FU (FOLFIRI) with and without DAVANAT(R), and oxaliplatin, leucovorin and 5 ... - Genetic Engineering News,

(PRN) Access Pharmaceuticals Announces the Commencement of a New ...  Feb 23, 2006
IND, is to demonstrate the ability of the tumor-targeting polymer system to deliver more platinum to tumors than can be attained with oxaliplatin, the approved ... - Houston Chronicle,

Recruitment Temporarily Suspended in an International Phase III ...  Feb 12, 2006
The XELOX regimen consists of capecitabine and oxaliplatin and the FOLFOX regimen consists of oxaliplatin, 5-FU and leucovorin. ... - PR Newswire (press release),

Chemotherapy Given Directly to Liver Improves Survival for ...  Feb 27, 2006
Because the research began in 1996, before chemotherapy drugs such as irinotecan and oxaliplatin were available, both sets of patients received fluorouracil ... - AScribe

(PRN) Access Pharmaceuticals Completes $5.0 Million Convertible ...  Feb 17, 2006
As reported previously, extensive preclinical and clinical data have shown better tolerability and efficacy profile of AP5346 over oxaliplatin, which is the ... - Houston Chronicle,

Avastin May Cause Leukoencephalopathy Syndrome  Mar 2, 2006
...of a 52-year-old woman with hypertension and metastatic rectal adenocarcinoma who had three cycles of chemotherapy with fluorouracil, leucovorin and oxaliplatin ... - Medscape (subscription)

March is Colorectal Cancer Awareness Month  Mar 1, 2006
..."Important medicines that have become part of the normal, gold- standard care in other G7 countries, such as Avastin or Oxaliplatin, are still not available to ... - CNW Telbec (Communiqués de presse),

Cancer Drug Trial on Hold  Feb 13, 2006
...of the study that looked at the effects of Avastin in combination with the chemotherapy treatment XELOX, which includes the drugs capecitabine and oxaliplatin. ... - Red Herring,

Genentech stops colon-cancer study  Feb 13, 2006
The patients in the Xelox treatment arm of Genentech's study -- where the higher event rate was seen -- are taking capecitabine and oxaliplatin, while the ... - United Press International

Genentech/Roche: trial delay won't choke Avastin's growth  Feb 13, 2006
...colorectal cancer patients, who will be given adjuvant treatment following surgery as one of three regimens: the FOLFOX regimen (oxaliplatin, leucovorin and 5 ... - Pharmaceutical Business Review

Mangafodipir appears to increase the cancer-killing ability of ...  Feb 20, 2006
...cells and white blood cells from 10 cancer patients and white blood cells from six control subjects to three chemotherapy drugs--paclitaxel, oxaliplatin, and 5 ... - News-Medical.net,

ImClone Systems Announces Complete Enrollment of Several Studies ...  Feb 16, 2006
The first of these studies, known as EPIC, examines the use of ERBITUX in metastatic colorectal cancer after failure of oxaliplatin-based chemotherapy. ... - Genetic Engineering News,

ImClone Systems Announces Complete Enrollment of Several Studies ...  Feb 16, 2006
The firstof these studies, known as EPIC, examines the use of ERBITUX inmetastatic colorectal cancer after failure of oxaliplatin-basedchemotherapy. ... - Finanzen.net,

Roche halts enrollment in Avastin trial  Feb 13, 2006
...in patients taking a combination of Avastin and Xelox (Roche's Xeloda [capecitabine] plus Sanofi-Aventis' cancer drug Eloxatin [oxaliplatin]) compared to those ... - Pharma Times (subscription),

Sanofi expects Acomplia launch in 06; profits up  Feb 24, 2006
Plavix (clopidogrel) and Lovenox (enoxaparin), while other big sellers such as the cancer drugs Taxotere (docetaxel) and Eloxatin (oxaliplatin) and Avapro ... - Pharma Times (subscription),

GEMOX Active in Recurrent Pancreatic Cancer  Feb 24, 2006
...published in the British Journal of Cancer, the chemotherapy combination consisting of Gemzar® (gemcitabine) plus Eloxatin® (oxaliplatin), referred to as ... - Cancer Consultants (press release),

Xaliproden May Reduce Side Effect Caused by Eloxatin® in ...  Feb 6, 2006
...to reduce the risk of peripheral neuropathy, a common side effect associated with the use of the chemotherapy agent Eloxatin® (oxaliplatin) in patients with ... - Cancer Consultants (press release),

Abgenix Announces 2005 Fourth Quarter and Full Year Financial ...  Feb 21, 2006
...the US Food and Drug Administration (FDA) for panitumumab in mCRC patients who have failed prior standard chemotherapy, including oxaliplatin and irinotecan. ... - Yahoo! News (press release)

Roche, Genentech suspend Avastin trial enrolment  Feb 13, 2006
...deaths in one of the three study arms, which involved patients taking Avastin plus the chemotherapy treatment XELOX, comprising Roche's Xeloda and oxaliplatin. ... - San Diego Union Tribune,

Pullback in Avastin drug trial  Feb 14, 2006
...some cross reaction between Avastin and the chemotherapy regimen XELOX, which includes Roche's Xeloda and another commonly used chemotherapy drug, oxaliplatin. - San Francisco Chronicle,

Common MRI Drug May Help Fight Cancer  Feb 14, 2006
The researchers studied the effects of three chemotherapy drugs -- paclitaxel, oxaliplatin and 5-fluorouracil -- on tumor cells and white blood cells from 10 ... - Forbes

Study Sets Treatment Standard for Elderly With Colon Cancer  Feb 10, 2006
...of the chemotherapy regimen known as FOLFOX4, a combination of the standard anticancer drugs 5-fluorouracil (5-FU), leucovorin and the new drug oxaliplatin. ... - DG News

Colon cancer chemotherapies OK for elderly  Feb 10, 2006
...cancer of the chemotherapy regimen known as FOLFOX4, a combination of the standard anti-cancer drugs 5-fluorouracil, leucovorin and the new drug oxaliplatin. ... - United Press International

Drugs Increase Chemotherapy's Cancer-Killing Abilities  Feb 14, 2006
...de Paul in Paris, and colleagues exposed tumor cells and white blood cells from cancer patients to three chemotherapy drugs -- paclitaxel, oxaliplatin, and 5 ... - Ivanhoe,

Pro-Pharmaceuticals Announces $10 Million Financing  Feb 15, 2006
The Company has been conducting clinical and pre-clinical studies with 5-FU, leucovorin, irinotecan, doxorubicin, oxaliplatin, paclitaxel, cisplatin, and ... - Genetic Engineering News,

Enrollment done in Erbitux cancer trials  Feb 16, 2006
...by ImClone, Bristol-Myers Squibb and Merck -- will test Erbitux in patients with metastatic colorectal cancer after failure of oxaliplatin-based chemotherapy. ... - United Press International

MRI Contrast Agent Enhances Chemotherapy's Cancer Killing  Feb 15, 2006
Cancer Institute. The drugs were Taxol (paclitaxel), Taxotere (docetaxel), Eloxatin (oxaliplatin), and 5-fluorouracil (5FU). In ... - MedPage Today,

Doxil®/Eloxatin® May Provide a Treatment Option in Advanced ...  Feb 6, 2006
...in Gynecologic Oncology, the chemotherapy combination consisting of Doxil® (pegylated liposomal doxorubicin) plus Eloxatin® (oxaliplatin) may provide an ... - Cancer Consultants (press release),

Breakthrough In The Design Of New Drugs - New Way Of Recognising ...  Feb 17, 2006
Three further platinum drugs (carboplatin - trade name ‘Paraplatin', nedaplatin and most recently oxaliplatin - trade name Eloxatin) are also in clinical use ... - Medical News Today (press release),

Concomitant oral administration of ketoconazole (a known inhibitor of CYP3A4 activity in the liver and in the intestinal mucosa) caused an eight-fold increase of the systemic exposure to oral budesonide. If treatment with inhibitors of CYP3A4 activity (such as ketoconazole, intraconazole, ritonavir, indinavir, saquinavir, erythromycin, etc.) is indicated, reduction of the budesonide dose should be considered. After extensive intake of grapefruit juice (which inhibits CYP3A4 activity predominantly in the intestinal mucosa), the systemic exposure for oral budesonide increased about two times. As with other drugs primarily being metabolized through CYP3A4, ingestion of grapefruit or grapefruit juice should be avoided in connection with budesonide administration.