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Botulinum Toxin
drug data and news
Botulinum Toxin drug data, resources, and news articles (when available). Onconews.org provides news on cancer research. This section, which includes profiles on medicines that may or not be cancer-related is in beta form. If things run smoothly we will be releasing a new format late in the summer of 2006.
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| Generic name | Botulinum Toxin | ||
| Brand Names/Synonyms | Botulinum neurotoxin type A precursor;BoNT/A;Bontoxilysin A;BOTOX[Contains: Botulinum neurotoxin A light- chain; Botulinum neurotoxin A heavy-chain]; BOTOX (Allegran Inc) | ||
| Indication | For treatment of cervical dystonia, axillary hyperhidrosis, strabismus, facial wrinkles | ||
| Sponsored links | Description | Purified botulinum toxin from Clostridium botulinum, purified from culture via dialysis and acid precipitation | |
| Pharmacology | Botox blocks neuromuscular transmission by binding to acceptor sites on motor or sympathetic nerve terminals, entering the nerve terminals, and inhibiting the release of acetylcholine. This inhibition occurs as the neurotoxin cleaves SNAP-25, a protein integral to the successful docking and release of acetylcholine from vesicles situated within nerve endings. | ||
| Mechanism Of Action | Not Available | ||
| Botulinum Toxin News (When available) |
Botulinum Toxin Type A (Botox) Effective For Up to 2 Years in ... 06 Mar 2006 SUFU 2006 - An Update on the Clinical Trials and Uses of Botulinum ... 06 Mar 2006 SUFU 2006 - Society for Urodynamics and Female Urology 2006 Winter ... 06 Mar 2006 PharmAthene wins 'orphan' approval for anthrax drug 06 Mar 2006 New Head-to-Head Study Shows Longer Duration of Effect and Greater ... Mar 3, 2006 New First-of-Its Kind Report Shows BOTOX(R) Cosmetic May Prevent ... Mar 3, 2006 Botox Could Help Target Resistant Tumors For Chemotherapy And ... Feb 20, 2006 ‘Bush lied, you lied’ Mar 3, 2006 Around South Florida Feb 25, 2006 DOR BioPharma Presents Positive New Survival Findings from Phase ... Feb 21, 2006 Excessive Sweating in Teens Can Cause Physical and Emotional ... Mar 2, 2006 Concerns Over Vitamin C, Botox Injections From Dubious Sources Feb 12, 2006 Nip and tuck without hassles of major surgery Feb 27, 2006 FANATIC OR HERO? THE LIFE OF AN ANIMAL ACTIVIST Feb 27, 2006 The genesis of a lie: How George Bush fabricated the Iraqi WMD ... Feb 21, 2006 Antitoxin for infant botulism slashes hospital stays Feb 8, 2006 CFIA: Health Hazard Alert-A & K Canned Sausages may Contain ... Feb 24, 2006 The Miracle of Botox - An Introduction (Part 1) Feb 2, 2006 Botox before the wrinkles Feb 20, 2006 Mentor Reports Third Quarter Financial Results Feb 6, 2006 Deja Vu All Over Again Feb 22, 2006 What is esophageal spasm? Feb 16, 2006 Threat of bioterrorism is all about hype in US Feb 22, 2006 Infant Botulism Drug Safe And Effective Feb 2, 2006 Botox Targets Resistant Tumors Feb 14, 2006 Botox aid against tumours Feb 15, 2006 How To Reduce Perspiration | Stop Excessive Sweating Feb 18, 2006 Doc on call Feb 15, 2006 Medical Edge: Many drug options for migraines Feb 11, 2006 Beauty is more than skin deep, you cosmetic clowns Feb 4, 2006 Bugging the water Feb 4, 2006 William Rivers Pitt: The Wack-Pack Feb 14, 2006 Allergan Gets Past Estimates Feb 2, 2006 "BIONOIA" Part 2 Jan 31, 2006 Botox Treatments at Botox Parties may be Dangerous Jan 31, 2006 Allergan Reports Fourth Quarter Operating Results Feb 2, 2006 The State of the Union Feb 1, 2006 | ||
| Dosage Forms | POWDER FOR SOLUTION | ||
| Drug_Category | Antidystonic Agents; Anti-Wrinkle Agents; unclassified therapeutic agents (92:00.00) | ||
| Absorption | Not Available | ||
| Interactions | Not Available | ||
| Toxicity | Not Available | ||
| Organisms Affected | Humans and other mammals | ||
| Chemical IUPAC Name | Not Available | ||
| Chemical Formula | C6760H10447N1743O2010S32 | ||
| Molecular Weight | 149322.7 | ||
| Smiles String | Not Available | ||
| Melting Point | Not Available | ||
| Water Solubility | Not Available | ||
| State | Not Available | ||
| LogP/Hphobicity | -0.368 | ||
| Isoelectric Point | 6.06 | ||
| Biotransformation | Not Available | ||
| Half Life | Not Available | ||
| Protein Binding [%] | Not Available | ||
| RxList Link | RXlist | ||
| Sponsored links | |||
| Drug Reference | http://www.rxlist.com/cgi/generic2/botulinumtoxin.htm | ||
| Drug Type | Approved Drug | ||
| Accession No | BIOD00092 | ||
| CAS Registry Number | Not Available | ||
| KEGG Compound ID | Not Available | ||
| PubChem ID | Not Available | ||
| PharmGKB ID | PA448659 | ||
| SwissProt ID | BXA1_CLOBO (P10845) | ||
| GenBank ID | X52066 | ||
| Drug ID Number [DIN] | 2243721 |
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