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Bethanechol
drug data and news
Bethanechol drug data, resources, and news articles (when available). Onconews.org provides news on cancer research. This section, which includes profiles on medicines that may or not be cancer-related is in beta form. If things run smoothly we will be releasing a new format late in the summer of 2006.
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| Generic name | Bethanechol | ||
| Brand Names/Synonyms | .Beta.-Methyl Carbachol Chloride; Amidopropyldimethylbetaine; B105; BTC; Besacholine; Bethaine Choline Chloride; Bethanechol; Bethanechol Chloride; C5259; CHEMBANK834; Carbamylmethylcholine Chloride; Duvoid; Mechotane; Mechothane; Mecothane; Mictone; Mictrol; Myocholine; Myotonachol; Myotonine Chloride; Urabeth; Urecholine; Urecholine Chloride; Uro-Carb | ||
| Indication | For the treatment of acute postoperative and postpartum nonobstructive (functional) urinary retention and for neurogenic atony of the urinary bladder with retention. | ||
| Sponsored links | Description | Not Available | |
| Pharmacology | Bethanechol is a parasympathomimetic (cholinergic) used for the treatment of acute postoperative and postpartum nonobstructive (functional) urinary retention and for neurogenic atony of the urinary bladder with retention. Bethanechol, a cholinergic agent, is a synthetic ester which is structurally and pharmacologically related to acetylcholine. It increases the tone of the detrusor urinae muscle, usually producing a contraction sufficiently strong to initiate micturition and empty the bladder. It stimulates gastric motility, increases gastric tone, and often restores impaired rhythmic peristalsis. Bethanechol chloride is not destroyed by cholinesterase and its effects are more prolonged than those of acetytcholine. | ||
| Mechanism Of Action | Bethanechol acts by selectively stimulating muscarinic receptors in the parasympathetic nervous system, inducing no affect on nicotinic receptors. | ||
| Bethanechol News (When available) |
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| Dosage Forms | TABLET | ||
| Drug_Category | Parasympathomimetics; ATC:N07AB02 | ||
| Absorption | Not Available | ||
| Interactions |
Interactions for Bethanechol: Special care is required if this drug is given to patients receiving ganglion blocking compounds because a critical fall in blood pressure may occur. Usually, severe abdominal symptoms appear before there is such a fall in the blood pressure. | ||
| Toxicity | Not Available | ||
| Organisms Affected | Humans and other mammals | ||
| Chemical IUPAC Name | 2-carbamoyloxypropyl-trimethyl-ammonium | ||
| Chemical Formula | C7H17N2O2 | ||
| Molecular Weight | 217-221 oC (chloride salt) | ||
| Smiles String | CC(C[N+](C)(C)C)OC(=O)N | ||
| Melting Point | Not Available | ||
| Water Solubility | 10 mg/mL (chloride salt) | ||
| State | Solid | ||
| LogP/Hphobicity | Not Available | ||
| Isoelectric Point | Not Available | ||
| Biotransformation | Not Available | ||
| Half Life | Not Available | ||
| Protein Binding [%] | Not Available | ||
| RxList Link | RXlist | ||
| Sponsored links | |||
| Drug Reference |
http://www.drugs.com/cons/Bethanechol.html http://www.rxlist.com/cgi/generic3/bethane.htm | ||
| Drug Type | Approved Drug | ||
| Accession No | APRD00051 | ||
| CAS Registry Number | 674-38-4 | ||
| KEGG Compound ID | C06850 | ||
| PubChem ID | SID:9068 | ||
| PharmGKB ID | PA448613 | ||
| SwissProt ID | Not Available | ||
| GenBank ID | Not Available | ||
| Drug ID Number [DIN] | 2237048 |
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