Antihemophilic Factor drug data and news

Antihemophilic Factor drug data, resources, and news articles (when available). Onconews.org provides news on cancer research. This section, which includes profiles on medicines that may or not be cancer-related is in beta form. If things run smoothly we will be releasing a new format late in the summer of 2006.

Generic name

Antihemophilic Factor

Brand Names/Synonyms

Coagulation factor VIII precursor;Procoagulant component;Antihemophilic factor;AHF; Human recombinant antihemophilic factor (AHF) or Factor VIII, 2332 residues, glycosylated, produced by CHO cells

Indication

For treatment of hemophilia A, von Willebrand diseae, Factor XIII deficiency

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Description

Human recombinant antihemophilic factor (AHF) or Factor VIII, 2332 residues, glycosylated, produced by CHO cells

Pharmacology

Binds factor IXa along with calcium and phospholipid, This complex converts factor X to factor Xa to facilitate clotting cascade.

Mechanism Of Action

Not Available

Antihemophilic Factor News
(When available)

Bayer's share price falls on 4Q results 06 Mar 2006
...in January 2005, as well as a good performance by erectile dysfunction drug Levitra (vardenafil), Kogenate (recombinant antihemophilic factor) and Trasylol ... - Pharma Times (subscription),

ZLB Behring Announces Availability of Humate-P(R) with Smaller ... Feb 15, 2006
15 /PRNewswire/ -- ZLB Behring today announced that Humate-P(R) (Antihemophilic Factor/von Willebrand Factor Complex (Human), Dried, Pasteurized) is now ... - PR Newswire (press release),

ZLB Behring Announces Availability of Humate-P with Smaller ... Feb 15, 2006
KING OF PRUSSIA, Penn., February 15, 2006 /PRNewswire/ -- ZLB Behring today announced that Humate-P(R) (Antihemophilic Factor/von Willebrand Factor Complex ... - PharmaLive.com (press release),

Baxter's ADVATE Achieves One Billion Unit Milestone Jan 31, 2006
Corporation, the leading global hemophilia therapy provider, announced today that accumulated sales of ADVATE(R) [Antihemophilic Factor (Recombinant), Plasma ... - PR Newswire (press release),

Cytyc 4Q Profit Rises to $33.4 Million and Baxter's ADVATE ... Feb 2, 2006
NYSE: BAX), the leading global hemophilia therapy provider, announced today that accumulated sales of ADVATE® [Antihemophilic Factor (Recombinant), Plasma ... - Financial News USA (press release),

Dosage Forms

POWDER FOR SOLUTION

Drug_Category

Coagulants; Thrombotic Agents; hemostatics (20:12.16)

Absorption

Not Available

Interactions

Not Available

Toxicity

Not Available

Organisms Affected

Humans and other mammals

Chemical IUPAC Name

Not Available

Chemical Formula

C11794H18314N3220O3553S83

Molecular Weight

264725.5

Smiles String

Not Available

Melting Point

Not Available

Water Solubility

Not Available

State

Not Available

LogP/Hphobicity

-0.533

Isoelectric Point

6.97

Biotransformation

Not Available

Half Life

8.4-19.3 hrs

Protein Binding [%]

Not Available

RxList Link

RXlist

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Drug Reference

http://www.drugs.com/cons/Antihemophilic_Factor.html
http://www.rxlist.com/cgi/generic2/hemofilm.htm

Drug Type

Approved Drug

Accession No

BIOD00029

CAS Registry Number

Not Available

KEGG Compound ID

Not Available

PubChem ID

Not Available

PharmGKB ID

PA448445

SwissProt ID

FA8_HUMAN (P00451)

GenBank ID

M14113

Drug ID Number [DIN]

2242491