Ampicillin drug data and news

Ampicillin drug data, resources, and news articles (when available). Onconews.org provides news on cancer research. This section, which includes profiles on medicines that may or not be cancer-related is in beta form. If things run smoothly we will be releasing a new format late in the summer of 2006.

Generic name Ampicillin
Brand Names/Synonyms AB-PC; AIC; AMPICILLIN; AY 6108; AY-6108; Ab-Pc Sol; Acillin; Adobacillin; Alpen; Amblosin; Amcill; Amfipen; Amfipen V; Aminobenzylpenicillin; Amipenix S; Ampen; Ampi; Ampi-Bol; Ampi-Co; Ampi-Tab; Ampichel; Ampicil; Ampicilina [Inn-Spanish]; Ampicillin; Ampicillin A; Ampicillin Acid; Ampicillin Anhydrate; Ampicillin Anhydrous; Ampicillin Base; Ampicillin Sodium; Ampicillin Trihydrate; Ampicillin [Usan:Ban:Inn:Jan]; Ampicillina [Dcit]; Ampicilline; Ampicilline [Inn-French]; Ampicillinum [Inn-Latin]; Ampicin; Ampifarm; Ampikel; Ampimed; Ampipenin; Ampipenin, Nt3; Ampiscel; Ampisyn; Ampivax; Ampivet; Amplacilina; Amplin; Amplipenyl; Amplisom; Amplital; Ampy-Penyl; Anhydrous Ampicillin; Austrapen; BA 7305; BRL; BRL 1341; BRL-1341; Bayer 5427; Binotal; Bonapicillin; Britacil; Campicillin; Cimex; Copharcilin; D-Ampicillin; D-Cillin; Delcillin; Deripen; Divercillin; Doktacillin; Duphacillin; Geocillin; Grampenil; Guicitrina; Guicitrine; HI 63; HSDB 3009; Lifeampil; Morepen; NCI-C56086; NSC 528986; NSC-528986; Norobrittin; Novo-Ampicillin; Nuvapen; Olin Kid; Omnipen; Omnipen-N; Orbicilina; P 50; P-50; Pen A; Pen Ampil; Pen a Oral; Penbristol; Penbritin; Penbritin Paediatric; Penbritin Syrup; Penbritin-S; Penbrock; Penicline; Penimic; Pensyn; Pentrex; Pentrexl; Pentrexyl; Pfizerpen A; Pfizerpen-A; Polycillin; Polycillin-N; Ponecil; Princillin; Principen; Principen '125'; Principen '250'; Principen '500'; Qidamp; Racenacillin; Ro-Ampen; Rosampline; Roscillin; SQ 17382; Semicillin; Semicillin R; Servicillin; Sk-Ampicillin; Spectrobid; Sumipanto; Supen; Synpenin; Texcillin; Tokiocillin; Tolomol; Totacillin; Totacillin-N; Totalciclina; Totapen; Trifacilina; Ultrabion; Ultrabron; Vampen; Viccillin; Viccillin S; WY-5103; Wypicil
Indication For treatment of infection (Respiratory, GI, UTI and meningitis) due to E. coli, P. mirabilis, enterococci, Shigella, S. typhosa and other Salmonella, nonpenicillinase-producing N. gononhoeae, H. influenzae, staphylococci, streptococci including streptoc
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Description Not Available
Pharmacology Ampicillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. The name "penicillin" can either refer to several variants of penicillin available, or to the group of antibiotics derived from the penicillins. Ampicillin has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. The bactericidal activity of Ampicillin results from the inhibition of cell wall synthesis and is mediated through Ampicillin binding to penicillin binding proteins (PBPs). Ampicillin is stable against hydrolysis by a variety of beta-lactamases, including penicillinases, and cephalosporinases and extended spectrum beta-lactamases.
Mechanism Of Action By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, Ampicillin inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that Ampicillin interferes with an autolysin inhibitor.
Ampicillin News
(When available)

Comval Board to probe 1000% alleged medicine overprice  06 Mar 2006
300%, 500%, 600%." Said Uy. Among the alleged overpriced medicines were Paracetamol, Penicillin and Ampicillin. Uy said that they ... - Philippine Information Agency,

Adamantane Resistance in Influenza A  Feb 21, 2006
Coincidentally, ampicillin was approved in the United States the same year that amantadine was. It seems almost quaint to review ... - Journal of American Medical Association (subscription),

Rethinking UTI Prophylaxis  Mar 1, 2006
1 This study demonstrates that ampicillin, nitrofurantoin, and third-generation cepholosporins may not be the appropriate initial therapy for patients with a ... - AAP Grand Rounds (subscription)

South Florida-based study on antibiotics could change treatment ...  Feb 3, 2006
April 2004 showed that antibiotics were the most commonly prescribed drugs for preemies, and that those treated with a combination of ampicillin and cefotaxime ... - Sun-Sentinel.com,

Fuel Prices: Where Are the Palliative Measures?  Feb 6, 2006
Ampicillin and cloxacillin which had dropped to about N600 per treatment course now approaches N1, 000. These are to mention but a few. ... - AllAfrica.com,

Pediatrix Data Mining Identifies Favorable Antibiotic Combination ...  Jan 27, 2006
Their peer-reviewed study, "Empiric Use of Ampicillin and Cefotaxime, Compared With Ampicillin and Gentamicin, for Neonates at Risk for Sepsis," appears in ... - Genetic Engineering News,

South Florida-based study on antibiotics could change treatment ...  Feb 3, 2006
April 2004 showed that antibiotics were the most commonly prescribed drugs for preemies, and that those treated with a combination of ampicillin and cefotaxime ... - Sun-Sentinel.com,

Fuel Prices: Where Are the Palliative Measures?  Feb 6, 2006
Ampicillin and cloxacillin which had dropped to about N600 per treatment course now approaches N1, 000. These are to mention but a few. ... - AllAfrica.com,

Tackling vaginal discharge irritation\  Jan 30, 2006
Inappropriate use of antibiotics of broad spectrum types eg tetracycline, ampicillin, ampiclox, septrin, etc. as in self-medication encourages candida growth. ... - The Tide,

Malaria, AIDS, Avian Flu, and MRSA-will we survive?  Jan 19, 2006
In Tanzania, for several decades, you could buy capsules of Tetracycline, Ampicillin, Chloramphenicol, etc, in almost any market in the country, even in the ... - IPP Media - Guardian,

Punjab: Pollution hits groundwater  Jan 31, 2006
...ingredients such as antibiotics, cephalosporins and 38 kinds of non-antibiotics, whereas DSM only produces amoxycillin, ampicillin and cloxacillin. ... - Central Chronicle,

Anti-dumping probe initiated on pen-G imports from China  Jan 21, 2006
...from China. Pen-G finds application in the manufacture of antibiotics such as ampicillin, amoxycillin and cloxacillin. While SPIC ... - Hindu Business Line,

American Pharmaceutical Partners Receives FDA Approval for ...  Nov 30, 2005
...injectables industry * APP is the only multi-source injectable company to offer 10 different classes of anti-infectives * Company's Ampicillin and Sulbactam ... - PR Newswire (press release),

(PRN) - American Pharmaceutical Partners Receives FDA Approval for ...  Nov 30, 2005
...(PRN) - Frost & Sullivan Recognizes Radant MEMS for Excellence in Technology Associated With Launching MEMS-Based RF Microswitches Into the MEMS Global Market ... - Bolsamania.com,

American Pharmaceutical Partners Receives FDA Approval for ...  Nov 30, 2005
...approval from the US Food and Drug Administration (FDA) for its Abbreviated New Drug Application (ANDA) for the combination drug Ampicillin and Sulbactam for ... - Yahoo! News (press release)

Rare Fatal Toxic Shock Reported Following Medical Abortions  Dec 1, 2005
In laboratory testing, C. sordellii has been demonstrated to be sensitive to antimicrobials such as penicillin, ampicillin, erythromycin, rifampin, tetracycline ... - CNN

APP gets FDA OK for generic Unasyn  Nov 30, 2005
The company said that the FDA approved the combination of injectable ampicillin and sulbactam, the active ingredients of Unasyn, in 1.5 gram and 3 gram single ... - BusinessWeek

Killer to serve at least 15 years  Dec 2, 2005
...went to Mr Shelley's Stafford home in March 2001, armed with duct tape, sticky tape, rope and a bottle of liquid containing white spirit, ampicillin and ecstasy ... - BBC News,

Orchid eyes $60 mn from new facility  Dec 2, 2005
The product range includes high-end betalactams such as Tazobactum+Piperacillin, Aztreonam and Ampicillin+Sulbactam injections, which are life-saving ... - Business Standard,

Will I conceive again after Injectaplan?  Dec 2, 2005
Ampicillin is such an antibiotic that may reduce the effect of a combined pill if both are taken together .However the combined pill is not known to delay ... - The Monitor, Uganda,

Practical Equine Medications  Dec 3, 2005
...of therapeutic benefit. Examples include ampicillin and related antibiotics. Injections are another familiar route. The three major ... - TheHorse.com,

Antibiotics segment ailing due to high input costs  Oct 17, 2005
While Cephalosporins continued to grow by 6.3 per cent, sales of others such as Quinolones and Ampicillin/Amoxycillan (used for throat infections, pneumonia ... - Hindu Business Line,

Prescribing medicine in Ramzan  Oct 20, 2005
Antibiotics like ampicillin, amoxicillin, erythromycin, cephalexin, tetracycline, penicillin etcetera which have to be taken six or eight hourly should not be ... - Independent-Bangladesh,

Sterling buys Torrent unit for $12.3 million  Oct 17, 2005
The company, based in Gujarat, had in its product portfolio the entire range of ß-lactum products such as amoxycillin trihydrate, ampicillin trihydrate and ... - in-PharmaTechnologist,

Sterling Biotech buys Torrent unit for Rs 55 cr  Oct 13, 2005
The company had in its product portfolio the entire range of ß-lactum products such as amoxycillin trihydrate, ampicillin trihydrate and cloxacillin sodium. ... - Business Standard,

Carrying the modern toxic load  Sep 30, 2005
...international food chain. The latest is a variety of maize that includes genetic information from the antibiotic ampicillin. Given the ... - The South African Journal of Natural Medicine (subscription),

Two Arrested After Agents Raid Spanish Grocery Store  Oct 11, 2005
One customer took the Spanish version of ampicillin, an antibiotic, and was rushed to Florida Hospital East with a severe allergic reaction. ... - WFtv.com,

Study: Failure of Initial Antibiotic Therapy Leads to Higher ...  Oct 7, 2005
...the study were treated primarily for cellulitis or post- operative wound infections and received either cefazolin, vancomycin, ampicillin-sulbactam, ceftriaxone ... - Yahoo! News (press release)

Grocers jailed in medication case  Oct 13, 2005
They said he treated a woman who suffered a severe allergic reaction to a Spanish version of ampicillin, an antibiotic, that she bought at the grocery without ... - Orlando Sentinel,

Jamaica receives $1.2 million in medical supplies from ADRA  Sep 29, 2005
The donation consisted of a variety of pharmaceutical products, such as ampicillin, ferrous sulphate, ibuprofen, multivitamin syrup, oral rehydration salts ... - ReliefWeb (press release),

Two Arrested After Agents Raid Spanish Grocery Store  11 Oct 2005
One customer took the Spanish version of ampicillin, an antibiotic, and was rushed to Florida Hospital East with a severe allergic reaction. ... - WFtv.com,

Study: Failure of Initial Antibiotic Therapy Leads to Higher ...  Oct 7, 2005
...the study were treated primarily for cellulitis or post- operative wound infections and received either cefazolin, vancomycin, ampicillin-sulbactam, ceftriaxone ... - Yahoo! News (press release)

Jamaica Receives $1.2 Million in Medical Supplies from ADRA  Sep 28, 2005
The donation consisted of a variety of pharmaceutical products, such as ampicillin, ferrous sulphate, ibuprofen, multivitamin syrup, oral rehydration salts ... - Reuters AlertNet,

Carrying the modern toxic load  Sep 30, 2005
...international food chain. The latest is a variety of maize that includes genetic information from the antibiotic ampicillin. Given the ... - The South African Journal of Natural Medicine (subscription),

The Spread of Antibiotic-Resistant Bacteria in Gulf Coast  Sep 22, 2005
The resistance started with penicillin, and then a new group of antibiotics were found, including ampicillin, and the bacteria became resistant to them. ... - ABC News

Doctor faces lawsuit over patient death  Sep 25, 2005
During visits, Alexanderian prescribed Valium, Vicodin, Darvocet, Darvon, Ampicillin, Motrin, Buspar and Soma Tabs with only a few examinations, the suit says. ... - Wilkes Barre Times-Leader,

Health ministry gets J$75-m in supplies  Sep 21, 2005
The donations, which came in three shipments, one by airlift and two by sea freight, include ampicillin, ferrous sulphate, ibuprofen, multivitamins syrup, oral ... - Jamaica Observer,

Nabi Biopharmaceuticals Receives Favorable Opinion From the ...  Sep 22, 2005
Resistance Issues Worldwide, over 95 percent of patients with S. aureus infections no longer respond to first-line antibiotics, such as penicillin or ampicillin ... - PR Newswire (press release),

The world is fast becoming fat and rotund. Is the industrially ...  Sep 13, 2005
150,000 tons of corn. This new corn variety contained a gene that makes it resistant to the antibiotic Ampicillin. It is widely ... - Planet Porto Alegre,

Why we banned imported drugs-Obasanjo  Sep 7, 2005
...a five-year moratorium to develop the capability to locally produce penicillin, the active ingredient in the popular antibiotics ampicillin/cloxacillin capsules ... - Daily Independent,

Inflation falls to 3.08 pc  Sep 2, 2005
Chemicals and chemical products' group index was down to 186.1 points owing to lower prices of ampicillin trihydrate (8t per cent) and bopp film (5 per cent). ... - Hindu Business Line,

Science of Sport: Eleutherococcus Senticosus - Can adaptogens help ...  Sep 3, 2005
...produces both ear and upper-respiratory tract infections, is now resistant to a variety of antibiotics, including chloramphenicol, ampicillin, and tetracycline ... - RunnersWeb,

GeoPharma Acquires Controlling Interest in Antibiotic ...  Aug 17, 2005
...with the five ANDAs in 10 dosage forms: Amoxicillin 250mg and 500mg oral capsule, Amoxicillin 125mg / 5ml and 250mg / 5ml suspensions, Ampicillin 250mg and ... - Pharmaceutical Processing,

Hunting good bacteria  Aug 27, 2005
...is also unique in that it is resistant to several commonly prescribed antibiotics, including ampicillin, amoxycillin, erythromycin, gentamycin, streptomycin ... - Malaysia Star,

Drug interactions with the pill  Aug 31, 2005
...cannot be relied upon. These include amoxicillin, ampicillin, metronidazole and tetracycline, to name a few. Antibiotics also may ... - Rochester Democrat and Chronicle,

Lyme Disease  Aug 30, 2005
If the diagnosis is Lyme disease, the treatment protocol normally will include antibiotics. Tetracyclines and ampicillin have been used successfully. ... - TheHorse.com,

Highlights From MMWR: Measles Outbreaks Underscore Need for ...  Aug 29, 2005
All 11 isolates tested for susceptibility to antibiotic therapy were ciprofloxacin-susceptible and ampicillin-resistant; nine isolates (82%) were resistant to ... - Medscape (subscription)

Fla. company takes Consolidated Pharmaceutical's drugs  Aug 16, 2005
...the products. The five ANDAs are for amoxicillin, ampicillin and penicillin v. potassium in various dosages and forms. The acquisitions ... - Baltimore Business Journal,

Weak medicine  Aug 16, 2005
..."We recently received bulk raw materials of Amoxicillin Trihydrate and Ampicillin Trihydrate that had no active ingredients at all, yet these are some of the ... - Standard,

The Housing Bubble Revisited  Aug 17, 2005
...was demonstrated that these triclosan-resistant mutants were also resistant to several antibiotics, specifically chloramphenicol, ampicillin, tetracycline and ... - HoweStreet.com,

SICK PSUS COME TO RESCUE OF MUMBAI  Aug 18, 2005
Similarly, HAL rushed sufficient supplies of IV Fluids, Ampicillin capsules and Norfloxacin tablets as required by the Maharashtra Health Department. ... - Press Information Bureau (press release),

It's Bye Bye to Ignorance  Aug 23, 2005
...they need to know how to identify wrong labeling of quantity and weight of active ingredients in drugs like 100 milligramme of ampicillin capsules falsely ... - Newswatch,

Dosage Forms POWDER FOR SOLUTION
Drug_Category Anti-bacterial Agents; Penicillins; ATC:J01CA01; ATC:J01CA02; ATC:J01CA06; ATC:J01CA14; ATC:J01CA15; ATC:S01AA19
Absorption Not Available
Interactions -->Interactions for Ampicillin:

When administered concurrently, the following drugs may interact with ampicillin.

Allopurinol: Increased possibility of skin rash, particularly in hyperuricemic patients may occur.

Bacteriostatic Antibiotics: Chloramphenicol, erythromycins, sulfonamides, or tetracyclines may interfere with the bactericidal effect of penicillins. This has been demonstrated in view, however, the clinical significance of this interaction is not well documented.

Oral Contraceptives: May be less effective and increased breakthrough bleeding may occur.

Probenecid: May decrease renal tubular secretion of ampicillin resulting in increased blood levels and/or ampicillin toxicity.

Drug/Laboratory Test Interaction

After treatment with ampicillin, a false-positive reaction for glucose in the urine may occur with copper sulfate tests (Benedict's solution, Fehling's solution, or Clinitest tablets) but not with enzyme based tests such as Clinistix and Glucose Enzymatic Test Strip USP.

Toxicity Not Available
Organisms Affected Enteric bacteria and other eubacteria
Chemical IUPAC Name 7-(2-amino-2-phenyl-acetyl)amino-3,3-dimethyl-6-oxo-2-thia-5-azabicyclo[3.2.0]heptane-4-carboxylicacid
Chemical Formula C16H19N3O4S
Molecular Weight 349.406 g/mol
Smiles String CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)O)C
Melting Point 208 °C
Water Solubility 1.01E+004 mg/L
State Solid
LogP/Hphobicity 1.35
Isoelectric Point Not Available
Biotransformation Not Available
Half Life Not Available
Protein Binding [%] Not Available
RxList Link RXlist
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Drug Reference http://www.drugs.com/cons/Ampicillin.html
http://www.rxlist.com/cgi/generic/ampicillin.htm
Drug Type Approved Drug
Accession No APRD00320
CAS Registry Number 69-53-4
KEGG Compound ID C06574
PubChem ID SID:149171
PharmGKB ID PA448419
SwissProt ID Not Available
GenBank ID Not Available
Drug ID Number [DIN] 2227029

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