|
Acrosoxacin
drug data and news
Acrosoxacin drug data, resources, and news articles (when available). Onconews.org provides news on cancer research. This section, which includes profiles on medicines that may or not be cancer-related is in beta form. If things run smoothly we will be releasing a new format late in the summer of 2006.
| Generic name |
Acrosoxacin
|
| Brand Names/Synonyms |
Acrosoxacin; Eracine; Eradacil; Eradacin; ROS; Rosoxacin; Rosoxacin [Usan:Inn]; Rosoxacine [Inn-French]; Rosoxacino [Inn-Spanish]; Rosoxacinum [Inn-Latin]; Roxadyl; Winuron |
| Indication |
For the treatment of Bacterial infection of respiratory tract, urinary tract, GI, CNS and immuno compromised patients |
|
Sponsored links
|
|
Description |
Not Available |
| Pharmacology |
Acrosoxacin is a nonfluorinated quinolone antibiotic. Its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase, which allows the untwisting required to replicate one DNA double helix into two. Acrosoxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. |
| Mechanism Of Action |
Acrosoxacin binds to and inhibits the enzymes topoisomerase II (DNA gyrase) and topoisomerase IV, which are required for bacterial DNA replication, transcription, repair, and recombination. |
Acrosoxacin News
(When available) |
[an error occurred while processing this directive] |
| Dosage Forms |
Not Available |
| Drug_Category |
Anti-Infective Agents |
| Absorption |
Not Available |
| Interactions |
Not Available |
| Toxicity |
Not Available |
| Organisms Affected |
Not Applicable |
| Chemical IUPAC Name |
1-ethyl-4-oxo-7-pyridin-4-yl-quinoline-3-carboxylic acid |
| Chemical Formula |
C17H14N2O3 |
| Molecular Weight |
294.305 g/mol |
| Smiles String |
CCN1C=C(C(=O)C2=C1C=C(C=C2)C3=CC=NC=C3)C(=O)O |
| Melting Point |
290 °C |
| Water Solubility |
Not Available |
| State |
Solid |
| LogP/Hphobicity |
2.404 |
| Isoelectric Point |
Not Available |
| Biotransformation |
Not Available |
| Half Life |
Not Available |
| Protein Binding [%] |
Not Available |
| RxList Link |
Not Available>RXlist |
|
Sponsored links
|
|
| Drug Reference |
Not Available |
| Drug Type |
Approved Drug |
| Accession No |
APRD00369 |
| CAS Registry Number |
40034-42-2 |
| KEGG Compound ID |
Not Available |
| PubChem ID |
SID:429531 |
| PharmGKB ID |
Not Available |
| SwissProt ID |
Not Available |
| GenBank ID |
Not Available |
| Drug ID Number [DIN] |
Not Available
|
|
|
