menotropins: profile and news

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Other information

Indication
For treatment of female infertility

Pharmacology
Used to treat female infertility, Menotropins stimulates late follicular maturation and resumption of oocyte meiosis, and initiates rupture of the pre-ovulatory ovarian follicle. Menotropins bind to the LH/hCG/FSH receptor of the granulosa and theca cells of the ovary to effect these changes in the absence of an endogenous LH surge.

Mechanism Of Action
Menotropins bind to the Follicle stimulating hormone receptor which results in ovulation in the absence of sufficient endogenous Luteinizing hormone.

Drug Category
Fertility Agents; gonadotropins (68:18.00)

Brand Names/Synonyms
Lutropin beta chain precursor;Luteinizing hormone beta subunit;LSH- beta;LSH-B;LH-B; Repronex

Dosage Forms
POWDER FOR SOLUTION

Absorption
Not Available

Interactions
Not Available

Chemical IUPAC Name
Mixture of luteinizing hormone and follicle stimulating hormone

Chemical Formula
C1014H1609N287O294S27 >BetaChain (LH) >AlphaChain (FSH) >beta chain (FSH)

Half Life
Not Available

Drug Type
Approved Drug

# Accession No
BIOD00018

CAS Registry Number
146479-72-3