Thyrotropin_Alfa: profile and news

Genzyme Reports Financial Results for the First Quarter of 2006 Apr 19, 2006
Sales of Thyrogen(R) (thyrotropin alfa for injection) increased 30 percent to $23 million in the first quarter, up from $17.7 million a year earlier. ... - MSN Money

Other information

Indication
For detection of residueal or recurrent thyroid cancer

Pharmacology
Binding of thyrotropin alfa to TSH receptors on normal thyroid epithelial cells or on well-differentiated thyroid cancer tissue stimulates iodine uptake and organification. Thyrogen is an exogenous source of human TSH that offers an additional diagnostic tool in the follow-up of patients with a history of well-differentiated thyroid cancer.

Mechanism Of Action
Binds to the thyrotropin receptors found on any residual thyroid cells or tissues. This stimulates radioactive iodine uptake for better radiodiagnostic imaging.

Drug Category
Diagnostic Agents; thyroid function (36:60.00)

Brand Names/Synonyms
Follitropin beta chain precursor;Follicle-stimulating hormone beta subunit;FSH-beta;FSH-B; Thyrogen (Genzyme Inc)

Dosage Forms
POWDER FOR SOLUTION

Absorption
Not Available

Interactions
Not Available

Chemical IUPAC Name
Human alpha thyrotropin

Chemical Formula
C975H1513N267O304S26 >beta chain

Half Life
5 +/- 10 hrs

Drug Type
Approved Drug

# Accession No
BIOD00020

CAS Registry Number
9002-71-5