Streptokinase: profile and news

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Other information

Indication
For lysis of acute pulmonary emboli, intracoronary emboli and management of myocardial infarction

Pharmacology
Streptokinase cleaves the Arg/Val bond in plasminogen to form plasmin. Plasmin in turn degrades the fibrin matrix of the thrombus, thereby exerting its thrombolytic action. This helps eliminate blood clots or arterial blockages that cause myocardial infarction.

Mechanism Of Action
Streptokinase cleaves the Arg/Val bond in plasminogen to form plasmin. This in turn leads to the degradation of blood clots.

Drug Category
Thrombolytic Agents

Brand Names/Synonyms
Streptokinase C precursor; Streptase

Dosage Forms
POWDER FOR SOLUTION

Absorption
Not Available

Interactions
Not Available

Chemical IUPAC Name
Streptococci streptokinase

Chemical Formula
C2100H3278N566O669S4

Half Life
Not Available

Drug Type
Approved Drug

# Accession No
BIOD00028

CAS Registry Number
1/1/9002