Renova: profile and news






Russia's Renova to explore for metals in Gabon  16 May 2006
MOSCOW (Reuters) - Russian oil-to-metals group Renova, controlled by tycoon Viktor Vekselberg, has secured a licence to explore for manganese, platinum group ... - Reuters South Africa,

Business in Brief  16 May 2006
NEW YORK -- Billionaire Viktor Vekselberg's Renova holding company won a license from Gabon to dig for gold and other metals in the West African country. ... - The Moscow Times,

Editorial: On courthouse steps  16 May 2006
SHOPMAN - Glass Shopman & Glazier Experienced shopman & gl....(more). SALES Hampton Inn Waco is excited to announce the completion of our renova....(more). ... - Waco Tribune Herald,

TNK-BP oil holding's net profit falls 28% in 1Q06  16 May 2006
...and BP's oil assets in Russia and Ukraine, TNK-BP is owned on a parity basis by BP, AAR consortium of Russia's Alfa Group, Access Industries and Renova. ... - RIA Novosti,

Liberty Media To Buy IDT Entertainment For Cash, Stock And ...  16 May 2006
In early March, IDT sold its Corbina Telecom business to a consortium of institutional and private investors headed by Renova Capital, for approximately $146 ... - Trading Markets,

Renova comes to Belarus  May 15, 2006
According to the Russian newspaper Vedomosti, "Renova Media Enterprises" company has acquired 50% shares of Cosmos TV company, a Belarusian cable TV operator. ... - E-Belarus.ORG,

Renova Energy sees sales growth  May 2, 2006
LONDON (SHARECAST) - Ethanol production firm Renova said there had been strong sales growth in the fourth quarter of 2005 and 2006. ... - ShareCast,

2 degrees of inspiration  May 12, 2006
On Sunday, Ambar Renova will call her mother 10 time zones away to wish her a Happy Mother's Day. It's a phone call Josefina Salcido ... - Arizona Republic,

Woman Awarded $1.27M After Leg Amputated  May 11, 2006
Mary Stewart sued Renova Health Center in Lake Park and its accounting services company, Universal Health Management, alleging hospital staff failed to treat ... - Forbes

Grandma who lost leg to maggots, wins $1.3 million lawsuit  May 11, 2006
Mary Stewart sued Renova Health Center in Lake Park and its parent company, Universal Health Management, alleging staff failed to treat her wound properly. ... - Sun-Sentinel.com,

Woman awarded $1.27 million after losing leg  May 10, 2006
...home. But when her doctor reexamined her after 18 days at Renova Health Center in Lake Park, what he found was hundreds of maggots. ... - Palm Beach Post,

Woman Gets $1.27 Million After Leg Infected With Maggots  May 11, 2006
Staff at Renova Health Center in Lake Park neglected to treat one of Mary Stewart's wound, the jury ruled Tuesday. The 72-year-old ... - NBC6.net,

West Palm Beach Woman Awarded $1.27 Million After Leg Amputated  May 11, 2006
A jury ruled Tuesday that staff at Renova Health Center in Lake Park neglected to treat one of Mary Stewart's wound. The 72-year ... - First Coast News,

Woman Gets $1.27 Million For Maggot-Infested Leg That Had To Be ...  May 11, 2006
A jury ruled Tuesday that staff at Renova Health Center neglected to treat one of Mary Stewart's wounds. Stewart, 72, said a nursing ... - Click10.com,

Woman wins lawsuit against nursing home over infestation of ...  May 10, 2006
...with maggots. Stewart sued the nursing home, Renova Health Center, and its parent company, Universal Health Management. On Wednesday ... - Sun-Sentinel.com,

Woman Awarded $1.27M After Leg Amputated  May 12, 2006
...clear how Wednesday‘s judgment will be paid because Universal Health Management is no longer in business and new owners have taken over Renova, the defendants ... - Ely Times,

Woman Awarded $1.27 Million After Maggot-Infected Leg Amputated  May 11, 2006
...surgery. Staff at Renova Health Center in Lake Park neglected to treat one of Mary Stewart's wound, the jury ruled Tuesday. WEIRD! ... - WFtv.com,

Volzhsky Orgsintez Turns Down  May 4, 2006
The Renova Group has offered Volzhsky Orgsintez (the Volga Organic Synthesis Plant) shareholders $100 million for 100 percent of the shares in that plant. ... - Kommersant,

Elderly Woman Wins $1.27 Million Lawsuit For Lost Leg Due To ...  May 11, 2006
FL (AHN) - An elderly woman won a $1.27 million lawsuit in court on Tuesday as jury members agreed that her leg wound was neglected at the Renova Health Center ... - All Headline News

Ural turbine works to take part in overhaul and updating of ...  May 12, 2006
Ural Turbine Works CJSC (part of Renova Group) will take part in overhaul and updating of turbines and boilers at Gyandjinskaya heating plant in Azerbaijan in ... - Ural Business Consulting,

Russia's Ural Turbine Works to update Ganja heating plant  May 12, 2006
According to Ural Business Consulting information agency, Ural Turbine Works CJSC (part of Renova Group) will take part in overhaul and updating of turbines ... - Today.Az,

Moscow CableCom Corp. Announces Private Placement of Equity ...  May 10, 2006
Renova Media Enterprises Ltd, formerly known as Columbus Nova Investments VIII Ltd., which before this private placement owned approximately 33.6% of the ... - Yahoo! News (press release)

Ural turbine works modernizes equipment of its machine-assembly ...  May 3, 2006
Uralsky Turbinny Zavod CJSC (Ural Turbine Works, member of RENOVA Group) proceeds with purchasing and modernization of production facilities within the ... - Ural Business Consulting,

Baylor student indicted for exposing himself in junior high ...  May 10, 2006
WANTED. Call A....(more). SALES Hampton Inn Waco is excited to announce the completion of our renova....(more). NIGHTCLUB - Help Needed. ... - Waco Tribune Herald,

Owner of Comcor TV contemplates private offering  May 12, 2006
...entitle investors participating in this placement to purchase one share per warrant for $9.852 after May 5. The company also said that Renova Media Enterprises ... - RosBusinessConsulting,

Could Perry end up with business tax increase and no cut?  May 10, 2006
Bosque Blvd. Payl....(more). SALES Hampton Inn Waco is excited to announce the completion of our renova....(more). MEDICAL DIRECT ... - Waco Tribune Herald,

Moscow CableCom outlines private equity placement  May 11, 2006
Renova Media Enterprises (former Columbus Nova Investments VIII), which before this private placement owned approximately 33.6 percent of CableCom and holds ... - Telecom Paper (subscription),

The Fly-Away Asset  May 10, 2006
Nevertheless, Deripaska may face competition of Renova’s owners and private holders of Vnukovo airport en route to Sochi asset. ... - Kommersant,

Natur Produkt Invest announced imminent bond issue  Apr 27, 2006
A direct investment fund, Renova Capital,that has become the holder of 40% of the company stock at the turn of 2004 considers regional expansion to be its ... - Cosmetics in Russia,

Moscow CableCom's revenues jump on subscriber growth  Apr 28, 2006
Moscow CableCom is currently utilising USD 10 million of proceeds received in the first quarter under the Renova Media term debt to continue its focus on ... - Telecom Paper (subscription),

What Is Cystic Acne and How to Treat This Acne  Apr 21, 2006
Tretinoin (Avita, Retin-A, Renova) and adapalene (Differin) are examples of topical prescription products for cystic acne derived from vitamin A. They work by ... - Fashion Monitor Toronto,

Rabotnicki running out of puff  May 5, 2006
...to compete in an end-of-season play-off against the third and fourth placed sides in the second division, Sileks will be keen to drag FK Renova, FK Vlazrimi ... - uefa.com,

Rain doesn't stop Leland Crawfish Festival  May 6, 2006
...“We represent a business called Cultural Expressions in Renova,� said Allison Hill. “We have with us all-handmade jewelry from Peru.�. ... - Delta Democrat Times,

Police report: Fire interrupts storm relief  May 6, 2006
PT Commission & Non Commission officers. ....more). SALES Hampton Inn Waco is excited to announce the completion of our renova....(more). - Waco Tribune Herald,

ONGC Videsh Ltd will bid for Russian firm on Friday  Apr 27, 2006
...is half-owned by British Petroleum, while the other half is owned by a group of Russian investors including the Alfa Group, Access Industries, and Renova (AAR ... - Daily News & Analysis,

Russia builds resource alliances with Africa  Apr 25, 2006
...ventures that have been seen in Africa already -- Norilsk Nickel's short-lived attempt to buy into, then take over Gold Fields; Renova's manganese licences in ... - Mineweb,

TOUCH VOTING  Apr 18, 2006
Lerch and Stouffer, poll workers at Lebanon's Fifth Ward west polling place, were in the basement of the Renova Center yesterday to learn how to use the ... - Patriot-News,

With over-the-counter products, get a million-dollar appearance ...  Apr 20, 2006
Rx: Retinoids, vitamin A derivatives, are commonly known by their brand names such as Retin-A, Avage and Renova, and are prescribed to address fine lines. ... - DetNews.com,

Russian Émigré Lives American Dream as Litigation Partner  Apr 29, 2006
He also has handled complex litigation for such clients as Pfizer, Kraft Foods, Sears and the Renova Group, a Russian holding company. ... - Texas Lawyer (subscription),

Manganese plot a la Milanese  Apr 17, 2006
Two notable Russians, steelmaker Alexander Abramov, owner of the Evraz group, and Victor Vekselberg, owner of the Renova multi-metals group, were also named as ... - Mineweb,

Moscow CableCom Corp. Announces 2005 Fourth Quarter and Twelve ...  Apr 27, 2006
We are currently utilizing $10 million of proceeds received in the first quarter under the Renova Media term debt to continue our focus on expanding network ... - Yahoo! News (press release)


Other information


Indication
For topical treatment of cutaneous lesions in patients with AIDS- related Kaposi sarcomaia.

Pharmacology
Alitretinoin (9-cis-retinoic acid) is a naturally-occurring endogenous retinoid indicated for topical treatment of cutaneous lesions in patients with AIDS- related Kaposi's sarcoma. Alitretinoin inhibits the growth of Kaposi's sarcoma (KS) cells in vitro.

Mechanism Of Action
Alitretinoin binds to and activates all known intracellular retinoid receptor subtypes (RARa, RARb, RARg, RXRa, RXRb and RXRg). Once activated these receptors function as transcription factors that regulate the expression of genes that control the process of cellular differentiation and proliferation in both normal and neoplastic cells.

Drug Category
Antineoplastic Agents; ATC:L01XX22

Brand Names/Synonyms
Alitretinoin; Alitretinoin [Usan]; Avita; Beta-Retinoic Acid; Panretin; Panretin Gel; Panretyn; Panrexin; Renova; Retin-A; Retin-a Micro; Retinoate; Retinoic Acid; Trans-Retinoic Acid; Tretin M; Tretinoin; Vesanoid; Vitamin a Acid

Dosage Forms
Not Available

Absorption
Not Available

Interactions
Interactions for Alitretinoin:

Patients who are applying Panretin® gel should not concurrently use products that contain DEET (N, N-diethyl-m-toluamide), a common component of insect repellent products. Animal toxicology studies showed increased DEET toxicity when DEET was included as proof of the formulation. Although there was no clinical evidence in the vehicle-controlled studies of drug interactions with systemic antiretroviral agents, including protease inhibitors, macrolide antibiotics, and azole antifungals, the effect of Panretin® gel on the steady-state concentrations of these drugs is not known. No drug interaction data are available on concomitant administration of Panretin® gel and systemic anti-KS agents.



Chemical IUPAC Name
3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)-nona-2,4,6,8-tetraenoicacid

Chemical Formula
C20H28O2

Half Life
Not Available

Drug Type
Approved Drug

# Accession No
APRD00017

CAS Registry Number
3/8/5300

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