Phenobarbital: profile and news

Arrests For Prescription Drug Crimes Increase May 15, 2006
Hall dorm room of freshman James Michael Lea last weekend and found about 30 prescription pills including Oxycontin, Xanax, Phenobarbital, Ambien, Lunesta ... - cbs4denver.com,

CU Police Make Prescription Drug Bust May 9, 2006
Daily Camera reported that the investigators found more than 80 items, including about 30 pills including Oxycontin, Xanax, Phenobarbital, Ambien, Lunesta ... - TheDenverChannel.com,

CU student accused of peddling prescription drugs May 9, 2006
...bag. The pills included Oxycotntin, Xanax, Phenobarbital, Ambien, Lunesta, Temazepam, Clonazepam, Vicodin, and Percocet. Police ... - 9NEWS.com,

Harris Turns to Holistic Healing for Pets May 10, 2006
His regular veterinarian diagnosed the dog as having epilepsy, and prescribed Phenobarbital and potassium bromide to help stop the seizures. ... - Westport-News,

Police say man swallowed drugs Apr 19, 2006
...warrant. Police searched the vehicle and found 6 grams of cocaine, 11 Phenobarbital pills and a small amount of marijuana. While ... - Hartselle Enquirer,

ASK DR. MICHAEL FOX Apr 22, 2006
...(Not even a cat will distract him.) I do give him Phenobarbital because when I first got him he was having seizures, which have stopped. ... - New York Post,

Bree Is Hooked on a Sex Addict May 1, 2006
An increased burden on her and her other son Matthew, he may soon become the victim of a phenobarbital overdose: "Just a few extra drops, he simply falls asleep ... - San Francisco Chronicle,

Deadline for Medicare drug plan nears May 3, 2006
...price. Whether a customer orders lorazepam for anxiety or phenobarbital for seizures, the members pay $60 for 360 tablets. It's ... - Daytona Beach News-Journal,

Vet faked euthanasia, Bucks lawsuit alleges Apr 28, 2006
Annie's diagnosis was idiopathic epilepsy — seizures for which no cause can be determined — and she was prescribed phenobarbital by Makem, according to the ... - Allentown Morning Call,

Desperate Housewives: April 30 May 1, 2006
Well, Betty has other plans for Caleb … to drug him up and/or kill him with Phenobarbital. Whoa! Matthew's devastated by the turn of events. ... - San Diego Union Tribune,

Zentiva NV 1st Quarter Results 2006 May 2, 2006
...local brands were Alcocalmin (metamizol) and Antinevralgic P (Paracetamolum, Cofein and Acidum Acetilsalicilicum), Etraveral (phenobarbital, valerian) and ... - PharmaLive.com (press release),

Anticonvulsant Treatment for Psychiatric and Seizure Indications ... May 4, 2006
...diagnosis of a psychiatric disorder only (1). A majority of those with a seizure disorder (66 percent) were given a prescription for phenobarbital or phenytoin ... - Psychiatric Services (subscription)

Other information

Indication
For the treatment of Epilepsy

Pharmacology
Phenobarbital, the longest-acting barbiturate, is used for its anticonvulsant and sedative-hypnotic properties in the management of all seizure disorders except absence (petit mal).

Mechanism Of Action
Phenobarbital acts on GABAA receptors, increasing synaptic inhibition. This has the effect of elevating seizure threshold and reducing the spread of seizure activity from a seizure focus. Phenobarbital may also inhibit calcium channels, resulting in a decrease in excitatory transmitter release. The sedative-hypnotic effects of phenobarbital are likely the result of its effect on the polysynaptic midbrain reticular formation, which controls CNS arousal.

Drug Category
Hypnotics and Sedatives; Anticonvulsants;

Brand Names/Synonyms
Adonal; Aephenal; Agrypnal; Amylofene; Aphenylbarbit; Aphenyletten; Barbenyl; Barbinal; Barbiphen; Barbiphenyl; Barbipil; Barbita; Barbivis; Barbonal; Barbophen; Bardorm; Bartol; Bialminal; Blu-Phen; Cabronal; Calmetten; Calminal; Cardenal; Chinoin; Codibarbita; Coronaletta; Cratecil; Damoral; Dezibarbitur; Dormina; Dormiral; Dormital; Doscalun; Duneryl; Ensobarb; Ensodorm; Epanal; Epidorm; Epilol; Episedal; Epsylone; Eskabarb; Etilfen; Euneryl; Fenbital; Fenemal; Fenobarbital; Fenosed; Fenylettae; Gardenal; Gardepanyl; Glysoletten; Haplopan; Haplos; Helional; Hennoletten; Henotal; Hypnaletten; Hypnette; Hypno-Tablinetten; Hypnogen; Hypnolone; Hypnoltol; Hysteps; Lefebar; Leonal; Lephebar; Lepinal; Lepinaletten; Linasen; Liquital; Lixophen; Lubergal; Lubrokal; Lumen; Lumesettes; Lumesyn; Luminal; Lumofridetten; Luphenil; Luramin; Molinal; Neurobarb; Nirvonal; Noptil; Nova-Pheno; Nunol; Parkotal; Pharmetten; Phen-Bar; Phenaemal; Phenemal; Phenemalum; Phenobal; Phenobarbital; Phenobarbitol; Phenobarbitone; Phenobarbituric Acid; Phenobarbyl; Phenoluric; Phenolurio; Phenomet; Phenonyl; Phenoturic; Phenylethylbarbiturate; Phenylethylbarbituric Acid; Phenylethylmalonylurea; Phenyletten; Phenyral; Phob; Polcominal; Promptonal; Seda-Tablinen; Sedabar; Sedicat; Sedizorin; Sedlyn; Sedofen; Sedonal; Sedonettes; Sevenal; Sinoratox; Sk-Phenobarbital; Solfoton; Solfoton Talpheno; Solu-Barb; Sombutol; Somnolens; Somnoletten; Somnosan; Somonal; Spasepilin; Starifen; Starilettae; Stental; Stental Extentabs; Talpheno; Teolaxin; Teoloxin; Thenobarbital; Theoloxin; Triabarb; Tridezibarbitur; Triphenatol; Versomnal; Zadoletten; Zadonal

Dosage Forms
Tablets and Elixir

Absorption
absorbed in varying degrees following oral, rectal or parenteral administration. The salts are more rapidly absorbed than are the acids. The rate of absorption is increased if the sodium salt is ingested as a dilute solution or taken on an empty stomach

Interactions