Paxil: profile and news
Research Reveals How Prozac Triggers New Brain Cell Growth 16 May 2006
TUESDAY, May 16 (HealthDay News) -- Experts have long suspected that one way antidepressants such as Prozac, Paxil and Zoloft dispel depression is by ... - Food Consumer,
Trial and Error 16 May 2006
And just this morning I heard that Paxil, a common anti-depressant my late husband took a decade ago, has now been found to increase suicide risk in adults. ... - Always On
Are You Sure You're Feeling OK? 16 May 2006
...another history of market expansion: the memorable publicity blitz that started with the FDA's 1999 approval of GlaxoSmithKline's antidepressant Paxil for a ... - AlterNet,
US cites suicidal acts on Paxil May 13, 2006
Reuters) - Young adults who took GlaxoSmithKline Plc's (GSK.L: Quote, Profile, Research) (GSK.N: Quote, Profile, Research) antidepressant Paxil in clinical ... - Reuters.uk,
Researchers getting the cold facts for women about hot flashes May 15, 2006
...last week in the Journal of the American Medical Association, it found that antidepressants such as fluoxetine (Prozac) and paroxetine (Paxil) appear to curb ... - Inside Bay Area,
Paxil letter warns docs May 13, 2006
WASHINGTON (AP) — The antidepressant Paxil may raise the risk of suicidal behavior in young adults, Glaxo-SmithKline and the Food and Drug Administration ... - Columbus Dispatch,
Use of Paxil may raise suicide risk, FDA says May 13, 2006
The antidepressant Paxil may raise the risk of suicidal behavior in young adults, GlaxoSmithKline and the Food and Drug Administration said yesterday in a ... - Winston-Salem Journal,
Antidepressant Paxil may raise suicide risk May 13, 2006
Washington — The antidepressant Paxil may raise the risk of suicidal behavior in young adults, GlaxoSmithKline and the Food and Drug Administration warned ... - Lawrence Journal World,
Paxil`s Maker Adds Suicide Attempt Warning May 13, 2006
...by Playfuls Team. The manufacturer of Paxil has notified doctors that the anti-depressant may increase the likelihood that young adults might attempt suicide. ... - Playfuls.com,
Paxil may up suicide risk May 13, 2006
WASHINGTON - The antidepressant Paxil could raise the risk of suicidal behavior in young adults, GlaxoSmithKline and the FDA warned Friday in a letter to ... - St. Petersburg Times,
FDA: Paxil linked to increased suicide risk in young adults May 13, 2006
Friday that a recent analysis showed "a higher frequency of suicidal behavior in young adults" who took the GlaxoSmithKline antidepressant Paxil compared to ... - Phoenix Business Journal,
GlaxoSmithKline, FDA Warn Paxil May Increase Suicide Risk In Young ... May 13, 2006
GlaxoSmithKline PLC (GSK | charts | news | PowerRating) and FDA, in a letter to doctors, on Friday, warned that taking the antidepressant Paxil may increase ... - Trading Markets,
Paxil Gets New Suicide Warning May 13, 2006
WASHINGTON -- Federal health officials are issuing a new warning of a possible link between the antidepressant Paxil and suicides. ... - News4Jax.com,
Health Warning: Paxil May Increase The Likelihood of Suicide May 13, 2006
The manufactures of the anti-depressant drug, Paxil, have notified doctors that the drug may actually increase the likelihood of suicide in young adults. ... - World Fitness,
Drug Company Warns Paxil May Increase Suicide Attempts May 13, 2006
New York, NY (AHN) - Maker of the antidepressant drug Paxil is warning doctors that the drug appears to increase the risk of suicide attempts in young adults. ... - All Headline News
Warning on Paxil/Suicide Risk May 13, 2006
Federal health officials are issuing a new warning of a possible link between the antidepressant Paxil and suicides in young adults. ... - WLNS,
Antidepressant Paxil Suspected To Raise Suicide Risk In Young ... May 13, 2006
Drug Company GlaxoSmithKline, Paxil's maker, issued a letter in which they notify doctors about a possible increase in suicidal thinking in young adults caused ... - Spotlighting News
Young Adults at Risk From Glaxo's Paxil BRIEFING: NEW YORK May 14, 2006
GlaxoSmithKline has sent letters to doctors warning that Paxil, its antidepressant drug, appears to increase the risk of suicide attempts in some young adults. ... - International News Service,
Paxil rises the Rate Of commiting Sucide...instead of fighting ... May 14, 2006
Glaxo Smith Kline and FDA had been sending letter to doctors on the 12th warning that the medicine Paxil might increase the rate of patients committing suicides ... - ProgressiveU.org,
Glaxo Warns of Paxil Suicide Attempts in Young Adults (Update4) May 12, 2006
Plc warned doctors that adults under the age of 30 may face an elevated risk of suicide attempts while taking its Paxil antidepressant, extending beyond ... - Bloomberg
US cites suicidal acts in adults on Glaxo's Paxil May 12, 2006
WASHINGTON (Reuters) - Young adults who took GlaxoSmithKline Plc's antidepressant Paxil in clinical trials were more likely to report suicidal behavior than ... - Malaysia Star,
Paxil`s maker adds suicide attempt warning May 12, 2006
WASHINGTON, DC, United States (UPI) -- The manufacturer of Paxil has notified doctors that the anti-depressant may increase the likelihood that young adults ... - Monsters and Critics.com,
FDA Warns of Suicide Risk for Paxil May 12, 2006
WASHINGTON May 12, 2006 (AP)— The antidepressant Paxil may raise the risk of suicidal behavior in young adults, GlaxoSmithKline and the Food and Drug ... - ABC News
GlaxoSmithKline warns Paxil may raise suicide risk May 12, 2006
The Food and Drug Administration and GlaxoSmithKline PLC (GSK) said Friday a recent analysis of clinical trials involving its antidepressant Paxil showed a ... - MarketWatch
Glaxo Warns of Paxil Suicide Risk in Young Adults (Update2) May 12, 2006
May 12 (Bloomberg) -- GlaxoSmithKline Plc informed doctors that its Paxil antidepressant appears to raise the risk of suicide in adults under the age of 30. ... - Bloomberg
GSK Releases Adult Paxil Suicide Data May 12, 2006
PLC confirmed Friday it voluntarily sent letters alerting thousands of doctors to changes made to the label of its antidepressant Paxil concerning young adults ... - Houston Chronicle,
Suicidal acts cited in adults on Glaxo's Paxil May 12, 2006
...recent analysis of clinical trial data found a higher rate of suicidal behavior among young adults who took GlaxoSmithKline's antidepressant Paxil than others ... - Reuters
Paxil Raises Suicide Risk For Young Adults May 12, 2006
GlaxoSmithkline, the makers of the antidepressant, Paxil, have warned that the drug may raise the risk of suicide attempts in people under 30. ... - Medical News Today,
GSK admits Paxil linked to suicide bids May 12, 2006
The drug giant GlaxoSmithKline has warned doctors in the US and the UK that its Paxil antidepressant appears to raise the risk of suicide in young adults. ... - Independent,
US cites suicidal acts in adults on Glaxo's Paxil May 12, 2006
...behavior among young adults who took GlaxoSmithKline Plc's (GSK.L: Quote, Profile, Research) (GSK.N: Quote, Profile, Research) antidepressant Paxil than others ... - Reuters
Paxil Suicide Risk in Young Adults May 12, 2006
May 12, 2006 -- The antidepressant Paxil and its controlled-release version, Paxil CR, are getting a new warning about suicide risk in young adults. ... - WebMD
Paxil Linked to Increased Suicidal Behavior in Young Adults May 12, 2006
RESEARCH TRIANGLE PARK, NC, May 12 — GlaxoSmithKline has warned physicians that patients ages 18 to 30 treated with Paxil (paroxetine) have a small but ... - MedPage Today,
FDA Requires Makers of Paxil to Include Warning of Suicide Risks ... May 12, 2006
By Freddie Mooche. (AXcess NEws) Washington - The Food and Drug Administration (FDA) is requiring the maker's of Paxil, an antidepressant, to include a warning ... - AXcess News,
GlaxoSmithKline Warns of Paxil Suicide Risk in Young Adults May 12, 2006
May 12, 2006 — The antidepressant Paxil and its controlled-release version, Paxil CR, are getting a new warning about suicide risk in young adults. ... - Newsinferno.com,
Drug maker warns of link between Paxil and suicide May 12, 2006
An analysis of clinical studies found Paxil, an antidepressant drug, increases the risk of suicidal behavior in young adults, marking the first time a ... - Newark Star Ledger,
Paxil and the risk of birth defects May 10, 2006
Early results of new studies for Paxil (paroxetine) suggest that the drug increases the risk of birth defects, particularly heart defects, when women take it ... - Pregnancy and Baby,
Drip Drip Drip - Paxil Info Leaks Out May 6, 2006
Such is the case with Paxil and as a result, unwitting patients continued to take the drug long after its dangers were known to GlaxoSmithKline. ... - SierraTimes.com
Paxil/Paxil CR and Recent Meta-Analysis of Paroxetine Showed a ... May 12, 2006
...professionals of changes to the Clinical Worsening and Suicide Risk subsection of the WARNINGS section in the prescribing Information for Paxil and Paxil CR. ... - PharmaLive.com (press release),
Medical Minute May 15, 2006
Another drug is under added scrutiny.. the anti-depressant Paxil. ... The FDA and Paxil's maker are adding that suicide risk warning to the drug's package inserts. ... - KHQA,
GSK admits Paxil linked to suicide bids May 13, 2006
The drug giant GlaxoSmithKline has warned doctors in the US and the UK that its Paxil anti-depressant appears to raise the risk of suicide in young adults. ... - Therapeutics Daily (subscription) (press release),
Health Highlights: May 13, 2006 May 13, 2006
Data from clinical trials indicates that the antidepressant drug Paxil appears to increase the risk of suicide attempts in some young adults, drug maker ... - Forbes
No Post-Partum Depression For Brooke Shields May 15, 2006
18th. After the birth, Shields said that she did not need the anti-depressant Paxil, that she had taken after her first delivery. ... - soFeminine.co.uk,
GlaxoSmithKline,FDA Notify Doctors Of Paxil Suicide Risk May 12, 2006
...professionals of changes to the Clinical Worsening and Suicide Risk subsection of the Warnings section in the prescribing Information for Paxil and Paxil CR. ... - Therapeutics Daily (subscription) (press release),
Paxil May Increase Suicide in Teens, FDA and GlaxoSmithKline May 12, 2006
WASHINGTON — The antidepressant Paxil may raise the risk of suicidal behavior in young adults, its manufacturer GlaxoSmithKline and the US Food and Drug ... - FOX News
Suicide label unlikely to squeeze Glaxo sales May 12, 2006
NEW YORK (CNNMoney.com) - GlaxoSmithKline added the increased risk of suicide for young adults to its Paxil label this week, but the antidepressant is past its ... - CNNMoney.com
Paxil May Trigger Suicidal Behavior in Young Adults May 12, 2006
The FDA stressed that all patients, especially young adults and those who are improving, should be carefully monitored when treated with Paxil. ... - Daily News Central,
Paxil May Increase Risk of Suicide Attempts, Drug Maker Warns May 12, 2006
Data from clinical trials indicates that the antidepressant drug Paxil appears to increase the risk of suicide attempts in some young adults, drug maker ... - KPHO Phoenix,
Paxil may raise suicide risk in young adults May 12, 2006
The widely prescribed antidepressant Paxil may raise the risk of suicidal behaviour in young adults, its manufacturer and the US Food and Drug Administration ... - Hamilton Spectator,
Other information
Indication
For the treatment of depression, depression accompanied by anxiety, obsessive compulsive disorder and panic attacks
Pharmacology
Paroxetine, an antidepressant drug of the selective serotonin reuptake inhibitor (SSRI) type, has no active metabolites and has the highest specificity for serotonin receptors of all the SSRIs. It is used to treat depression resistant to other antidepressants, depression complicated by anxiety, panic disorder, social and general anxiety disorder, obsessive-compulsive disorder (OCD), premenstrual dysphoric disorder, premature ejaculation, and hot flashes of menopause in women with breast cancer.
Mechanism Of Action
Paroxetine is a potent and highly selective inhibitor of neuronal serotonin reuptake. Paroxetine likely inhibits the reuptake of serotonin at the neuronal membrane, enhances serotonergic neurotransmission by reducing turnover of the neurotransmitter, therefore it prolongs its activity at synaptic receptor sites and potentiates 5-HT in the CNS; paroxetine is more potent than both sertraline and fluoxetine in its ability to inhibit 5-HT reuptake. Compared to the tricyclic antidepressants, SSRIs have dramatically decreased binding to histamine, acetylcholine, and norepinephrine receptors.
Drug Category
Antidepressants; Selective Serotonin Reuptake Inhibitors (SSRIs); ATC:N06AB05
Brand Names/Synonyms
Aropax; FG 7051; Paroxetina [Inn-Spanish]; Paroxetine; Paroxetine Hcl; Paroxetine [Usan:Ban:Inn]; Paroxetinum [Inn-Latin]; Paxil; Paxil Cr; Pexeva; Seroxat
Dosage Forms
Tablet
Absorption
completely absorbed after oral dosing
Interactions