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Ask the Clinician: Answers to Readers' Questions May 1, 2006
...her neck. I fear her condition is getting worse even after resuming her MAOI regimen of Parnate and occasional Klonopin. Is there ... - About - News & Issues,

Other information

Indication
Depression

Pharmacology
Tranylcypromine belongs to a class of antidepressants called monoamine oxidase inhibitors (MAOIs). Tranylcypromine works by irreversibly blocking the action of a chemical substance known as monoamine oxidase (MAO) in the nervous system. Within neurons, MAO appears to regulate the levels of monoamines released upon synaptic firing. Since depression is associated with low levels of monoamines, the inhibition of MAO serves to ease depressive symptoms.

Mechanism Of Action
The irreversible inhibition of MAO by Tranylcypromine causes an increase in the levels of serotonin, norepinephrine, and dopamine in the neuron, relieving depressive symptoms.

Drug Category
Anti-anxiety Agents; Antidepressants; Antidepressants; ATC:N06AF04

Brand Names/Synonyms
Dl-Tranylcypromine; Parnate; SKF 385; Transamine; Tranylcypromine

Dosage Forms
TABLET

Absorption
Not Available

Interactions
Interactions for Tranylcypromine:

No Information Provided.

Chemical IUPAC Name
2-phenylcyclopropan-1-amine

Chemical Formula
C9H11N

Half Life
Not Available

Drug Type
Approved Drug

# Accession No
APRD00645

CAS Registry Number
155-09-9