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Necon: profile and news
CAAN yet to recover dues from air operators Feb 21, 2006 Michael Ledeen: "regime change" for Iran, Syria Dec 9, 2005 AMERICANS ARE RUNNING OUT OF PATIENCE WITH THEIR `WAR PRESIDENT’ Nov 14, 2005 Minting (unpaid) air miles! Dec 2, 2005 NOC halts fuel supply to airlines owing dues Nov 17, 2005 NOC stops fuel supply to 3 airlines, domestic flights disrupted Nov 17, 2005 INEC, Owerri bye-election and burden of credible polls Nov 17, 2005 Lies of the Neocons: From Leo Strauss to Scooter Libby Nov 9, 2005 Iwu’s burden of proof for credible polls Oct 9, 2005 Rice v. PNAC Sep 13, 2005 Lack of awareness, laws leave investors high and dry Aug 19, 2005 Aviation Policy Compromising National Interests Jul 5, 2005 Aviation Policy Compromising National Interests Jul 5, 2005 July Joy Jun 22, 2005 CCCE Not Happy With Minority Government Jun 28, 2005 Joining for Monsoon wash? Jun 20, 2005 July Joy Jun 22, 2005 Joining for Monsoon wash? Jun 20, 2005 Book released Apr 17, 2005 A New Path for INEC? Apr 1, 2005 ATOMIC IRAN: Simply Crazy, or Crazy Like a Fox? Apr 8, 2005 7 terrorists killed in action Apr 7, 2005 An Interview with Sonya Taaffe Apr 4, 2005 Pay Rs 540m to CAAN, CIAA tells 24 airlines Mar 4, 2005 CIAA asks CAAN to realize dues from the airlines Mar 5, 2005 Other information Indication For treatment of moderate to severe vasomotor symptoms associated with the menopause, female hypogonadism, prostatic carcinoma-palliative therapy of advanced disease, breast cancer, as an oral contraceptive, and as emergency contraceptive. Pharmacology Ethinyl estradiol is a synthetic derivative of the natural estrogen estradiol. It is one of two estrogens currently used in oral contraceptive pills. The other, mestranol, is converted to ethinyl estradiol before it is biologically active. Ethinyl estradiol and norethindrone are used together as an oral contraceptive agent. Mechanism Of Action Estrogens diffuse into their target cells and interact with a protein receptor. Target cells include the female reproductive tract, the mammary gland, the hypothalamus, and the pituitary. Estrogens increase the hepatic synthesis of sex hormone binding globulin (SHBG), thyroid-binding globulin (TBG), and other serum proteins and suppress follicle-stimulating hormone (FSH) from the anterior pituitary. The combination of an estrogen with a progestin suppresses the hypothalamic-pituitary system, decreasing the secretion of gonadotropin-releasing hormone (GnRH). Drug Category Estrogens; ATC:G03CA01 Brand Names/Synonyms 17?-Ethynylestradiol; 17alpha-Ethinylestradiol; 17alpha-Ethynylestradiol; 17alpha-Ethynyloestradiol; Aethinyloestradiolum; Aethinyoestradiol [German]; Alesse; Alora; Amenoron; Amenorone; Anovlar; BRN 2419975; Binovum; Brevicon; Brevinor; CCRIS 286; CHEMBANK1139; Climara; Conceplan; Cyclosa; Demulen; Desogen; Dicromil; Diognat-E; Diogyn E; Diogyn-E; Diprol; Dyloform; EE; EE2; EO; ETHINYLESTRADIOL; Ertonyl; Esclim; Esteed; Estigyn; Estinyl; Eston-E; Estopherol; Estoral; Estoral {[Orion]}; Estorals; Estrace; Estraderm; Estradiol; Estring; Estrogel; Estrogen; Ethidol; Ethinoral; Ethinyl Estradiol; Ethinyl-Oestranol; Ethinylestradiolum [Inn-Latin]; Ethinylestriol; Ethinyloestradiol; Ethy 11; Ethynylestradiol; Ethynyloestradiol; Eticyclin; Eticyclol; Eticylol; Etinestrol; Etinestryl; Etinilestradiol [Inn-Spanish]; Etinilestradiolo [Dcit]; Etinoestryl; Etistradiol; Etivex; Feminone; Fempatch; Follicoral; Genora; Ginestrene; Gynodiol; Gynolett; HSDB 3587; Halodrin; Inestra; Innofem; Jenest; Kolpolyn; Levlen; Linoral; Lo/Ovral; Loestrin; Logynon; Lynoral; Marvelon; Menolyn; Menostar; Mercilon; Microfollin; Microgynon; Mircette; Modicon; NEE; NSC-10973; Necon; Nelova; Neo-Estrone; Neocon; Nogest-S; Norcept; Nordette; Norethin 1/35 E; Norimin; Norinyl; Norlestrin; Novestrol; Oradiol; Orestralyn; Orestrayln; Ortho Tri-Cyclen; Ortho-Cept; Ortho-Cyclen; Ortho-Novum; Ovcon; Ovex; Oviol; Ovral; Ovran; Ovranette; Ovysmen; Palonyl; Perovex; Primogyn; Primogyn C; Primogyn M; Progynon C; Progynon M; Prosexol; Spanestrin; Stediril; Synphase; Tetragynon; Thiuram E; Thiuranide; Tri-Levlen; Tri-Norinyl; Trinordiol; Trinovum; Triphasil; Vagifem; Varnoline; Vivelle; Ylestrol Dosage Forms DISC (SUSTAINED-RELEASE); GEL; IMPLANT; LIQUID; PATCH; RING (SLOW-RELEASE); SOLUTION; TABLET Absorption Rapid and complete absorption follows oral intake of ethinyl estradiol (bioavailability 43%). Interactions Drug Interactions for Ethinyl Estradiol: Certain endocrine and liver function tests may be affected by estrogen-containing oral contraceptives. The following similar changes may be expected with larger doses of estrogen: Increased sulfobromophthalein retention; increased prothrombin and factors VII, VIII, IX, and X; decreased antithrombin 3; increased norepinephrine-induced platel et aggregation; increased thyroid binding globulin (TBG) leading to increased circulating total thyroid hormone, as measured by PBI, T4 by column, or T4 by radioimmunoassay. Free T3 resin uptake is decreased, reflecting the elevated TBG; free T4 concentration is unaltered: impaired glucose tolerance; decreased pregnanediol excretion; reduced response to metyrapone test; reduced serum folate concentration; increased serum triglyceride and phospholipid concentration. Chemical IUPAC Name 17-ethynyl-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol Chemical Formula C20H24O2 Half Life 36 +/- 13 hours Drug Type Approved Drug # Accession No APRD00691 CAS Registry Number 57-63-6 |
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