Necon: profile and news






CAAN yet to recover dues from air operators  Feb 21, 2006
Rs 448.9 million, Royal Nepal Army has Rs 949,000, Gorkha Airlines Rs 5.4 million, Karnali Airlines Rs 2.5 million, Skylines Rs 3 million, Necon Airlines Rs ... - Nepalnews.com,

Michael Ledeen: "regime change" for Iran, Syria  Dec 9, 2005
In the Nov. 30 National Review Online, he takes the Bush administration on for retreating from the maximalist necon agenda to reshape the Middle East. ... - World War 4 Report,

AMERICANS ARE RUNNING OUT OF PATIENCE WITH THEIR `WAR PRESIDENT’  Nov 14, 2005
The FBI’s Libby investigation could produce a blizzard of embarrassing evidence of how the White House’s necon Praetorian Guard engineered the US into war. ... - Foreign Correspondent,

Minting (unpaid) air miles!  Dec 2, 2005
...million. RA owes Rs 510 million! Necon Air, which has remained grounded since last three years, owes Rs 45 million. The airline ... - Kathmandu Post,

NOC halts fuel supply to airlines owing dues  Nov 17, 2005
...million from various airlines. Of the total, RNAC alone owes Rs 510 million. Necon Air also owes Rs 45 million to the authority. - Kathmandu Post,

NOC stops fuel supply to 3 airlines, domestic flights disrupted  Nov 17, 2005
...receive around Rs 610 million from various airlines. Of the total, RNAC alone owes Rs 510 million while Necon Air owes Rs 45 million. - Kantipur Online,

INEC, Owerri bye-election and burden of credible polls  Nov 17, 2005
There had existed the Federal Electoral Commission (FEDECO), National Electoral Commission (NEC), National Electoral Commission of Nigeria (NECON) before INEC. ... - Daily Independent,

Lies of the Neocons: From Leo Strauss to Scooter Libby  Nov 9, 2005
Others stars in the necon firmament are Richard Perle, Douglas Feith and lesser figures like Abram Shulsky, director of the Pentagon's Office of Special Plans ... - OpEdNews

Iwu’s burden of proof for credible polls  Oct 9, 2005
Nwosu, March 17, 1989 to 1992; Professor Okon Edet Uya, July 1993 to October 1993; Dr. Dagogo Jack, National Electoral Commission of Nigeria (NECON) 1994 to ... - Daily Independent,

Rice v. PNAC  Sep 13, 2005
And the necon HQ is placing Op-eds in the Washington Post that argue not for democracy in Iraq, but for a ruthless tyranny of the majority. - TomPaine.com,

Lack of awareness, laws leave investors high and dry  Aug 19, 2005
Similar is the plight of Sunil Dev, another small investor, who bought 7,000 unit shares of Necon Air at the value of Rs 245 each from the secondary market. ... - Kathmandu Post,

Aviation Policy Compromising National Interests  Jul 5, 2005
Some have already closed down. The first to close shop was Nepal Airways in 1997 while the last to shut down is Necon Air in 2003. ... - Gorkhapatra <**results**>

Aviation Policy Compromising National Interests  Jul 5, 2005
Some have already closed down. The first to close shop was Nepal Airways in 1997 while the last to shut down is Necon Air in 2003. ... - Gorkhapatra

July Joy  Jun 22, 2005
His outdoor furniture, which won Best of Show at Necon 2004, the interior design show, reflects the monolithic forms that he's become famous for. ... - Upstate House

CCCE Not Happy With Minority Government  Jun 28, 2005
Ah, see, so it's not that nothing is getting done--it's that some things are getting done that aren't part of their usual super pro-corporate necon agenda. ... - Vive Le Canada

Joining for Monsoon wash?  Jun 20, 2005
Two stranded ATRs leased by Necon are awaiting their third monsoon wash off since the airline packed out with millions in unpaid bills. ... - Kathmandu Post,

July Joy  Jun 22, 2005
His outdoor furniture, which won Best of Show at Necon 2004, the interior design show, reflects the monolithic forms that he's become famous for. ... - Upstate House,

Joining for Monsoon wash?  Jun 20, 2005
Two stranded ATRs leased by Necon are awaiting their third monsoon wash off since the airline packed out with millions in unpaid bills. ... - Kathmandu Post,

Book released  Apr 17, 2005
...written by RK Gunachandra of Awang Potshangbam who works as in-charge of Dimapur Branch of North Eastern Industrial Consultants Limited (NECON) has been ... - E-Pao.net

A New Path for INEC?  Apr 1, 2005
...government of General Sani Abacha, which earlier dissolved NEC in 1993, established the National Electoral Commission of Nigeria (NECON), which conducted ... - AllAfrica.com

ATOMIC IRAN: Simply Crazy, or Crazy Like a Fox?  Apr 8, 2005
East experts at AEI and other neocon policy centers; Michael Ledeen, who Amitay called the “godfather of JINSA, and who has served as the necon’s point-man ... - Payvand

7 terrorists killed in action  Apr 7, 2005
Three terrorists — Baburam of Manpur area of Dang, Bijaya Adhikary and Kamal BK alias ‘Necon’ of Kalikot district — were killed in the security ... - Gorkhapatra

An Interview with Sonya Taaffe  Apr 4, 2005
...at once? How’d it happen? The epic version is, I attended Necon 24 in July 2004. I’d never been to a convention before. I had ... - Bookslut,

Pay Rs 540m to CAAN, CIAA tells 24 airlines  Mar 4, 2005
...“Otherwise, we will intervene.� According to the CIAA, the airlines, including the state-owned Royal Nepal Airlines Corporation, Necon Air, Cosmic Air ... - Himalayan Times,

CIAA asks CAAN to realize dues from the airlines  Mar 5, 2005
...run Gorkhapatra daily, the airlines that have not paid their dues to the treasury include the state-owned Royal Nepal Airlines Corporation, Necon Air (that ... - Nepalnews.com,


Other information


Indication
For treatment of moderate to severe vasomotor symptoms associated with the menopause, female hypogonadism, prostatic carcinoma-palliative therapy of advanced disease, breast cancer, as an oral contraceptive, and as emergency contraceptive.

Pharmacology
Ethinyl estradiol is a synthetic derivative of the natural estrogen estradiol. It is one of two estrogens currently used in oral contraceptive pills. The other, mestranol, is converted to ethinyl estradiol before it is biologically active. Ethinyl estradiol and norethindrone are used together as an oral contraceptive agent.

Mechanism Of Action
Estrogens diffuse into their target cells and interact with a protein receptor. Target cells include the female reproductive tract, the mammary gland, the hypothalamus, and the pituitary. Estrogens increase the hepatic synthesis of sex hormone binding globulin (SHBG), thyroid-binding globulin (TBG), and other serum proteins and suppress follicle-stimulating hormone (FSH) from the anterior pituitary. The combination of an estrogen with a progestin suppresses the hypothalamic-pituitary system, decreasing the secretion of gonadotropin-releasing hormone (GnRH).

Drug Category
Estrogens; ATC:G03CA01

Brand Names/Synonyms
17?-Ethynylestradiol; 17alpha-Ethinylestradiol; 17alpha-Ethynylestradiol; 17alpha-Ethynyloestradiol; Aethinyloestradiolum; Aethinyoestradiol [German]; Alesse; Alora; Amenoron; Amenorone; Anovlar; BRN 2419975; Binovum; Brevicon; Brevinor; CCRIS 286; CHEMBANK1139; Climara; Conceplan; Cyclosa; Demulen; Desogen; Dicromil; Diognat-E; Diogyn E; Diogyn-E; Diprol; Dyloform; EE; EE2; EO; ETHINYLESTRADIOL; Ertonyl; Esclim; Esteed; Estigyn; Estinyl; Eston-E; Estopherol; Estoral; Estoral {[Orion]}; Estorals; Estrace; Estraderm; Estradiol; Estring; Estrogel; Estrogen; Ethidol; Ethinoral; Ethinyl Estradiol; Ethinyl-Oestranol; Ethinylestradiolum [Inn-Latin]; Ethinylestriol; Ethinyloestradiol; Ethy 11; Ethynylestradiol; Ethynyloestradiol; Eticyclin; Eticyclol; Eticylol; Etinestrol; Etinestryl; Etinilestradiol [Inn-Spanish]; Etinilestradiolo [Dcit]; Etinoestryl; Etistradiol; Etivex; Feminone; Fempatch; Follicoral; Genora; Ginestrene; Gynodiol; Gynolett; HSDB 3587; Halodrin; Inestra; Innofem; Jenest; Kolpolyn; Levlen; Linoral; Lo/Ovral; Loestrin; Logynon; Lynoral; Marvelon; Menolyn; Menostar; Mercilon; Microfollin; Microgynon; Mircette; Modicon; NEE; NSC-10973; Necon; Nelova; Neo-Estrone; Neocon; Nogest-S; Norcept; Nordette; Norethin 1/35 E; Norimin; Norinyl; Norlestrin; Novestrol; Oradiol; Orestralyn; Orestrayln; Ortho Tri-Cyclen; Ortho-Cept; Ortho-Cyclen; Ortho-Novum; Ovcon; Ovex; Oviol; Ovral; Ovran; Ovranette; Ovysmen; Palonyl; Perovex; Primogyn; Primogyn C; Primogyn M; Progynon C; Progynon M; Prosexol; Spanestrin; Stediril; Synphase; Tetragynon; Thiuram E; Thiuranide; Tri-Levlen; Tri-Norinyl; Trinordiol; Trinovum; Triphasil; Vagifem; Varnoline; Vivelle; Ylestrol

Dosage Forms
DISC (SUSTAINED-RELEASE); GEL; IMPLANT; LIQUID; PATCH; RING (SLOW-RELEASE); SOLUTION; TABLET

Absorption
Rapid and complete absorption follows oral intake of ethinyl estradiol (bioavailability 43%).

Interactions
Drug Interactions for Ethinyl Estradiol:

Certain endocrine and liver function tests may be affected by estrogen-containing oral contraceptives. The following similar changes may be expected with larger doses of estrogen:

Increased sulfobromophthalein retention; increased prothrombin and factors VII, VIII, IX, and X; decreased antithrombin 3; increased norepinephrine-induced platel et aggregation; increased thyroid binding globulin (TBG) leading to increased circulating total thyroid hormone, as measured by PBI, T4 by column, or T4 by radioimmunoassay. Free T3 resin uptake is decreased, reflecting the elevated TBG; free T4 concentration is unaltered: impaired glucose tolerance; decreased pregnanediol excretion; reduced response to metyrapone test; reduced serum folate concentration; increased serum triglyceride and phospholipid concentration.



Chemical IUPAC Name
17-ethynyl-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol

Chemical Formula
C20H24O2

Half Life
36 +/- 13 hours

Drug Type
Approved Drug

# Accession No
APRD00691

CAS Registry Number
57-63-6

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