Nasacort: profile and news

OTC Decongestant Nothing To Sneeze At Feb 21, 2006
He notes that nasal steroid sprays, like Flonase, Nasacort, and Rhinocort, are considered the first-line prescription drugs for the treatment of hay fever. ... - CBS News

Sanofi-aventis Third Quarter 2005: Adjusted EPS(1) up 27.4%, Net ... Nov 7, 2005
14.8% 661 +14.2% Amaryl(R) 195 +19.6% 542 +12.2% Actonel(R) 99 +20.7% 275 +25.6% Depakine(R) 81 +5.2% 238 +5.3% Xatral(R) 80 +15.9% 237 +16.2% Nasacort(R) 65 ... - PR Newswire (press release),

Fall allergies Aug 19, 2005
...for her. Not even the prescriptions drugs Nasacort, Singulair and Zyrtec, which she is taking right now, are working. These medications ... - Blue Springs Examiner,

Strong net sales growth in the first half of 2005: 11.0% on a ... Jul 19, 2005
27.3% 406 +23.8% Amaryl(R) 191 +7.9% 347 +8.4% Actonel(R) 96 +26.3% 176 +28.5% Depakine(R) 83 +10.7% 157 +5.4% Xatral(R) 78 +20.0% 157 +16.3% Nasacort(R) 74 ... - Canada NewsWire (press release)

Sanofi-aventis Announces Strong Net Sales Growth in the First Half ... Jul 18, 2005
27.3% 406 +23.8% Amaryl® 191 +7.9% 347 +8.4% Actonel® 96 +26.3% 176 +28.5% Depakine® 83 +10.7% 157 +5.4% Xatral® 78 +20.0% 157 +16.3% Nasacort® 74 +7.2 ... - Yahoo News (press release) <**results**>

Allergy medications: Know your options Jun 25, 2005
...nose. Examples include budesonide (Rhinocort), mometasone (Nasonex), fluticasone (Flonase) and triamcinolone (Nasacort). Although ... - MayoClinic.com

Allergies bloom, costs loom Apr 3, 2005
Jim Eller of All Souls Unitarian Universalist Church in Kansas City stopped using Nasacort nasal spray this year after his copay jumped from $30 to $50 for a 30 ... - Kansas City Star

Allergy Sufferers Brace For Tough Spring Mar 30, 2005
Prescription steroid nasal sprays, sold under such names as Flonase, Nasacort and Nasonex, are the most effective hay fever treatment. ... - 10News.com

Medicines Help Nip Allergy Season in the Bud Apr 12, 2005
Examples include Beconase, Rhinocort, Nasarel, Flonase, Nasonex and Nasacort, which are all prescription-only. Mast cell stabilizers. ... - Press-Enterprise (subscription),

Cold or Allergies Mar 26, 2005
...such as an antihistamine like Claritin, Clarinex, Zyrtec, or Allergra, or a nasal steroid like Nasonex, Rhinocort Aqua, Flonase, or Nasacort AQ, you should ... - pediatrics.about.com

Other information

Indication
For the treatment of perennial and seasonal allergic rhinitis

Pharmacology
Triamcinolone and its derivatives are synthetic glucocorticoids that are used for their antiinflammatory or immunosuppressive properties.

Mechanism Of Action
The antiinflammatory actions of corticosteroids are thought to involve lipocortins, phospholipase A2 inhibitory proteins which, through inhibition of arachidonic acid, control the biosynthesis of prostaglandins and leukotrienes. The immune system is suppressed by corticosteroids due to a decrease in the function of the lymphatic system, a reduction in immunoglobulin and complement concentrations, the precipitation of lymphocytopenia, and interference with antigen-antibody binding.

Drug Category
Glucocorticoids; Anti-inflammatory Agents; Adrenergic Agents; ATC:A01AC01; ATC:D07AB09; ATC:D07XB02; ATC:H02AB08; ATC:R01AD11; ATC:R03BA06; ATC:S01BA05

Brand Names/Synonyms
Adcortyl; Aristocort; Aristocort A; Aristocort Tablets; Aristogel; Aristospan; Azmacort; CL 19823; Celeste; Cinolone; Cinolone-T; Delphicort; Fluoxiprednisolone; Fluoxyprednisolone; Flutex; HSDB 3194; Kenacort; Kenacort-A; Kenacort-Ag; Kenalog; Kenalog in Orabase; Kenalog-10; Kenalog-40; Kenalog-H; Ledercort; Nasacort; Nasacort Aq; Nasacort Hfa; Omcilon; Omicilon; Oracort; Oralone; Orion; Polcortolon; Rodinolone; Sk-Triamcinolone; Tiamcinolonum [Inn-Latin]; Tri-Nasal; Triacet; Triacort; Triam-Tablinen; Triamcet; Triamcinalone; Triamcinlon; Triamcinolon; Triamcinolona [Inn-Spanish]; Triamcinolone; Triamcinolone Acetonide; Triamcinolone Acetonide in Absorbase; Triamcinolone Diacetate; Triamcinolone [Usan:Ban:Inn:Jan]; Triamcinolonum [Inn]; Triatex; Tricortale; Triderm; Trymex; Vetalog; Volon

Dosage Forms
CREAM; LIQUID; METERED-DOSE (AEROSOL); OINTMENT; PASTE; SUSPENSION; SYRUP; TABLET

Absorption
Rapid absorption following oral administration

Interactions
Not Available

Chemical IUPAC Name
9-fluoro-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

Chemical Formula
C21H27FO6

Half Life
88 minutes

Drug Type
Approved Drug

# Accession No
APRD00422

CAS Registry Number
124-94-7