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MetroGel: profile and news
Study Compares Once-daily Metronidazole 1% Gel to Twice-daily ... 07 Mar 2006 New Beauty: Coping with life in rosacea's red zone Nov 28, 2005 Fougera Receives First Tentative Generic Approval for MetroGel(R) Sep 16, 2005 FDA Approvals: Aptivus, MetroGel, Topamax Jul 21, 2005 Dow Pharmaceutical Sciences Announces FDA Approval of METROGEL(R) ... Jul 6, 2005 Dow Pharmaceutical Sciences Announces FDA Approval of METROGEL ... Jul 6, 2005 New treatment for rosacea Jul 6, 2005 Dow Pharmaceutical Sciences Announces FDA Approval of METROGEL(R) ... Jul 6, 2005 Dow Pharmaceutical Sciences Announces FDA Approval of METROGEL ... Jul 6, 2005 New treatment for rosacea Jul 6, 2005 Other information Indication Treatment of acute acne rosacea Pharmacology Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea. Mechanism Of Action Unionized metronidazole is selective for anaerobic bacteria due to their ability to intracellularly reduce metronidazole to its active form. This reduced metronidazole then disrupts DNA's helical structure, inhibiting bacterial nucleic acid synthesis and resulting in bacterial cell death. Drug Category Radiation-Sensitizing Agents; Antiprotozoals; Anti-Infectives; Antiprotozoals; ATC:A01AB17; ATC:D06BX01; ATC:G01AF01; ATC:J01XD01; ATC:P01AB01 Brand Names/Synonyms Acromona; Anagiardil; Apo-Metronidazole; Arilin; Atrivyl; Bayer 5360; Benzoylmetronildazole; Bexon; Clont; Cont; Danizol; Deflamon; Deflamon-Wirkstoff; Efloran; Elyzol; Entizol; Eumin; Flagemona; Flagesol; Flagil; Flagyl; Flagyl Er; Flagyl I.V.; Flagyl I.V. Rtu; Flegyl; Fossyol; Giatricol; Gineflavir; Helidac; Klion; Klont; Meronidal; Methronidazole; Metric 21; Metro Cream &Amp; Gel; Metro I.V.; Metro I.V. In Plastic Container; Metrocream; Metrogel; Metrogel-Vaginal; Metrolag; Metrolotion; Metrolyl; Metromidol; Metronidaz; Metronidazol; Metronidazole; Metronidazole Benzoate; Metronidazole Hcl; Metronidazole in Plastic Container; Metronidazolo; Metrotop; Mexibol; Monagyl; Monasin; Nalox; Neo-Tric; Nida; Nidagel; Noritate; Novonidazol; Orvagil; Protostat; RP 8823; Rathimed; Sanatrichom; Satric; Takimetol; Trichazol; Trichex; Tricho Cordes; Tricho-Gynaedron; Trichocide; Trichomol; Trichomonacid 'Pharmachim'; Trichopal; Trichopol; Tricocet; Tricom; Tricowas B; Trikacide; Trikamon; Trikojol; Trikozol; Trimeks; Trivazol; Vagilen; Vagimid; Vertisal; Wagitran; Zadstat Dosage Forms Tablets, IV injection Absorption well absorbed Interactions -->Interactions for Metronidazole: Oral metronidazole has been reported to potentiate the anticoagulant effect of coumarin and warfarin, resulting in a prolongation of prothrombin time. Drug interactions should be kept in mind when METROGELÒ (metronidazole gel), 1% is prescribed for patients who are receiving anticoagulant treatment, although they are less likely to occur with topical metronidazole administration because of low absorption. |
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