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Methyltestosterone: profile and news
Murray must see off Chela to set up match with home favourite Jan 12, 2006 FACTBOX-List of players banned for doping Jan 11, 2006 Sex shop sold laced drugs Jan 16, 2006 I’M 18, DON’T EXPECT ME TO WIN EVERY GAME, SAYS MURRAY Jan 16, 2006 Lannett Company Launches New Generic Product Sep 15, 2005 Brazilian pro surfer first to test positive for steroids in the ... Sep 20, 2005 Surfer barred from 2005 competition for steroid use Sep 21, 2005 Padaratz busted for steroid use Sep 22, 2005 NHL ads strike the right chord with hockey fans Sep 25, 2005 Juice controversy spills onto courts Aug 30, 2005 Canas angry at doping ban Aug 9, 2005 ATP 'made a mistake' says Canas Aug 9, 2005 Pair held in steroid bust Aug 12, 2005 Testosterone Patch Improves Sexual Desire Jul 25, 2005 Canas fails dope test Jun 22, 2005 Canas fails dope test Jun 22, 2005 Men's matches go the distance Jun 2, 2005 Nothing fishy about our tilapia Mar 29, 2005 Steroids and sports: A dangerous mix? Feb 15, 2005 Other information Indication For topical testosterone replacement therapy in males with deficiency or absence of testosterone Pharmacology Testosterone is an antineoplastic hormonal agent primarily used in the treatment of prostate cancer. Testosterone is a pure, nonsteroidal anti-androgen with affinity for androgen receptors (but not for progestogen, estrogen, or glucocorticoid receptors). Consequently, Testosterone blocks the action of androgens of adrenal and testicular origin which stimulate the growth of normal and malignant prostatic tissue. Prostate cancer is mostly androgen-dependent and can be treated with surgical or chemical castration. To date, antiandrogen monotherapy has not consistently been shown to be equivalent to castration. Mechanism Of Action Testosterone competes with androgen for the binding of androgen receptors, consequently blocking the action of androgens of adrenal and testicular origin which stimulate the growth of normal and malignant prostatic tissue. Drug Category Antineoplastic Agents; Anabolic Agents; Androgens; ATC:G03BA02; ATC:G03BA03; ATC:G03EK01 Brand Names/Synonyms AA 2500; Andriol; Andro; Andro 100; Andro L.A. 200; Androderm; Androgel; Android 10; Android 25; Android 5; Androlin; Andronaq; Andronate 100; Andronate 200; Andropatch; Andropository 200; Andrusol; Andryl 200; Beta Testosterone; CCRIS 574; CDB 111C; COL 1621; CP 601B; Cristerona T; Cristerone T; Dea No. 4000; Delatest; Delatestryl; Depo-Testosterone; Depo-Testosterone Cypionate; Depotest; Dofsol; Everone 200; Geno-Cristaux Gremy; HSDB 3398; Homosteron; Homosterone; Libigel; Malerone; Malestrone; Malogen in Oil; Malogen, Aquaspension Injection; Mertestate; Metandren; Methyltestosterone; NSC 9700; Neo-Hombreol F; Neo-Testis; Neotestis; Oreton; Oreton F; Oreton Methyl; Oreton-F; Orquisteron; Perandren; Percutacrine Androgenique; Primotest; Primoteston; Relibra; Scheinpharm Testone-Cyp; Striant; Sustanon; Sustanone; Sustason 250; Synandrol F; T-Cypionate; TES; Teslen; Testamone 100; Testandrone; Testaqua; Testex; Testiculosterone; Testim; Testobase; Testoderm; Testoderm Tts; Testogel; Testoject-50; Testolin; Testopel Pellets; Testopropon; Testosteroid; Testosteron; Testosterona [Inn-Spanish]; Testosterone; Testosterone Cypionate; Testosterone Enanthate; Testosterone Hydrate; Testosterone Propionate; Testosterone [Ban:Inn]; Testosterone and Its Esters; Testosteronum [Inn-Latin]; Testostosterone; Testoviron; Testoviron Schering; Testoviron T; Testred; Testred Cypionate 200; Testrin-P.A; Testro Aq; Testrone; Testryl; Trans-Testosterone; Virilon; Virilon Im; Virormone; Virosterone Dosage Forms CAPSULE; GEL; LIQUID; PATCH; SOLUTION; SUSPENSION Absorption Approximately 10% of the testosterone dose applied on the skin surface from AndroGel® is absorbed into systemic circulation Interactions -->Interactions for Testosterone: Oxyphenbutazone: Concurrent administration of oxyphenbutazone and androgens may result in elevated serum levels of oxyphenbutazone. Insulin: In diabetic patients, the metabolic effects of androgens may decrease blood glucose and, therefore, insulin requirements. Propranolol: In a published pharmacokinetic study of an injectable testosterone product, administration of testosterone cypionate led to an increased clearance of propranolol in the majority of men tested. Corticosteroids: The concurrent administration of testosterone with ACTH or corticosteroids may enhance edema formation; thus, these drugs should be administered cautiously, particularly in patients with cardiac or hepatic disease. Drug/Laboratory Test Interactions Androgens may decrease levels of thyroxin-binding globulin, resulting in decreased total T4 serum levels and increased resin uptake of T3 and T4. Free thyroid hormone levels remain unchanged, however, and there is no clinical evidence of thyroid dysfunction. |
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