Methylin: profile and news

Ph.D., Bonnie Slade: Parent worried about son's AD/HD medication  Mar 3, 2006
As you may know, there recently has been news about stimulant medications such as Ritalin, Concerta, Adderall, Methylin and Metadate. ... - Sebastian Sun (subscription),

New Vaccine Helping Against Rotavirus  Feb 21, 2006
...hospitalized. Other medications making headlines are the ones used to treat ADHD (Ritalin, Concerta, Methylin and Metadate. Adderall ... - WFIE-TV,

FDA panel calls for warning on Ritalin  Feb 10, 2006
Drugs that would have to carry the warning labels are methylphenidates, which are sold as Ritalin, Concerta, Methylin and Metadate. ... - Indianapolis Star,

Feds recommend warnings on ADHD drugs  Feb 10, 2006
...however, the committee voted 8-7 to recommend requiring black box warnings on methylphenidates, which are sold as Ritalin, Concerta, Methylin and Metadate. ... - San Jose Mercury News,

FDA may add warnings to attention-deficit drugs  Feb 10, 2006
...health advisers recommended Thursday that such a warning be added to labels on Ritalin and other methylphenidates, which include Concerta, Methylin and Metadate ... - Canton Repository (subscription),

Feds Consider Warnings on ADHD Drugs  Feb 9, 2006
...hypertension. The drugs include amphetamines, such as Adderall, and methylphenidates, sold as Ritalin, Concerta, Methylin and Metadate. ... - ABC News

Hyperactivity Drugs Prove Deadly to 25  Feb 9, 2006
...panel will meet today to discuss new ways of examining the potential cardiovascular risks of the drugs, which include Ritalin, Concerta, Methylin and Metadate. - Los Angeles Times,

ZyDoc Alerts Doctors with Patients Affected by ADHD Drug Warnings ...  Feb 28, 2006
Attention Deficit Hyperactivity Disorder (ADHD) medications in the methylphenidate and amphetamine classes, including Ritalin, Concerta, Methylin, Metadate and ... - PR Web (press release),

Drug deaths detailed by FDA  Feb 9, 2006
...potential cardiovascular risks of the drugs, which include amphetamines such as Adderall, and methylphenidates, sold as Ritalin, Concerta, Methylin and Metadate ... - Bradenton Herald,

DEATHS TIED TO ATTENTION-DEFICIT DRUGS  Feb 9, 2006
...cardiovascular risks of the drugs, which include amphetamines, including Adderall, and methylphenidates, sold as Ritalin, Concerta, Methylin and Metadate. ... - Amherst Times.com,

FDA Panel Calls for Strongest Warning on ADHD Drugs  Feb 9, 2006
...voted 8-7, with one abstention, to add a "black box" warning to the drugs, which include methylphenidates such as Ritalin, Concerta, Methylin and Metadate. ... - drkoop.com

Drug Warning  Feb 10, 2006
...each month. But the warning label that comes on drugs like Ritalin, Concerta, Methylin and Metadate could soon be changing. "Our ... - WRIC,

Deaths Tied to Attention-Deficit Drugs  Feb 11, 2006
...labels might be needed on the drugs, which include amphetamines, such as Adderall, and methylphenidates, sold as Ritalin, Concerta, Methylin and Metadate. ... - International News Service,

Feds Recommend Warnings on ADHD Drugs  Feb 9, 2006
...to consider ways of studying the drugs, which include amphetamines, such as Adderall, and methylphenidates, sold as Ritalin, Concerta, Methylin and Metadate. ... - ABC News

Attention-Deficit Drugs Need Added Warnings, US Advisers Say  Feb 9, 2006
...and Alliant Pharmaceuticals Inc.'s Methylin. Todd Gruber, medical-safety director for Novartis, said Ritalin is the most-studied drug in its class. ... - Bloomberg

Attention Drugs Need Strictest Warning, Panel Says (Update2)  Feb 9, 2006
Other stimulants include Johnson & Johnson's Concerta, Novartis's Focalin, and Tyco International Ltd. and Alliant Pharmaceuticals Inc.'s Methylin. ... - Bloomberg

ADHD Individual Drug Risk Studies To Be Considered By Drug Safety ...  Feb 8, 2006
...s Dexedrine and Dexedrine Spansules), methylphenidate (J&J’s Concerta, Novartis’ Ritalin, Ritalin SR, and Ritalin LA; Alliant’s Methylin and Methylin ER ... - FDA Advisory Committee

Vancouver's Chapter Of Citizens Commission on Human Rights ...  Feb 13, 2006
The drugs in question were amphetamines such as Adderall, and methylphenidates, sold as Ritalin, Concerta, Methylin and Metadate for children and adults with ... - Eworldwire (press release),

Caution advised in use of Ritalin  Feb 20, 2006
ADHD drugs, including Ritalin, Adderall, Concerta, Methylin and Metadate are prescribed to an estimated 2 million children and 1 million adults per month in ... - Wilson Daily Times (subscription),

Attention-Deficit Drugs Need Watching, US FDA Says (Update1)  Feb 8, 2006
...and Alliant Pharmaceuticals Inc.'s Methylin, Concerta and Ritalin, which is also sold as a generic product, are made of the stimulant methylphenidate. ... - Bloomberg

FDA Probes ADHD Deaths  Feb 9, 2006
Adderall, Eli Lilly’s Strattera, Concerta from McNeil Consumer & Specialty Pharmaceuticals, Alliant Pharmaceuticals’ Methylin, and Celltech Pharmaceuticals ... - Red Herring,

Warning Urged for ADHD Drugs  Feb 9, 2006
The panel called for warning labels on methylphenidate drugs, sold under the brand names Ritalin, Concerta, Methylin and Metadate, and on the amphetamines ... - Washington Post,

FDA panel calls for strongest warning on ADHD drugs  Feb 9, 2006
...box warning about possible cardiovascular side effects; the advisory panel recommended a similar warning be added to Ritalin, Concerta, Methylin and Metadate. ... - Chicago Tribune,

US advisors recommend safety warnings against attention deficit ...  Feb 9, 2006
The advisory committee said ADHD drugs, including amphetamines, such as Adderall, and methylphenidates, sold as Ritalin, Concerta, Methylin and Metadate ... - People's Daily Online,

Black box warning called for ADHD drugs  Feb 9, 2006
Such druggs include adderall, Ritalin, Concerta, Methylin and Metadate. While not binding, the advisory panels' recommendations usually are followed. ... - Xinhua,

FDA Panel Recommends Black Box Warning on ADHD Drugs - Ritalin and ...  Feb 9, 2006
...warning are Adderall (made by Shire Pharmaceuticals), Ritalin (made by Novartis Pharmaceuticals Corp.), Concerta (made by Johnson & Johnson), Methylin (made by ... - Best Syndication,

FDA Panel Suggests Adding Black Box Warning to ADHD Medications ...  Feb 10, 2006
The panel recommended warning labels for methylphenidate drugs -- sold as Ritalin, Concerta, Methylin and Metadate, as well as the amphetamines Adderall and ... - Kaiser network.org,

Warnings Advised on ADHD Drugs  Feb 10, 2006
...the committee to consider what types of studies could be used to look at whether the drugs, which include Ritalin, Adderall, Focalin, Methylin, Metadate and ... - Sci-Tech Today

Re-examining ADHD drugs  Feb 17, 2006
The FDA report details 25 deaths of individuals who were taking one of the popular ADHD drugs - such as Adderall, Ritalin, Concerta and Methylin - between 1999 ... - myDNA.com,

FDA Debates ADHD Drug Warning  Feb 18, 2006
...to the Food and Drug Administration recently voted to place a "black box" warning on the medicines, which include Ritalin, Concerta, Methylin and Metadate. ... - Lakeland Ledger,

FDA ties 25 deaths to hyperactivity drugs  Feb 8, 2006
An FDA panel was to discuss today new ways of examining the potential cardiovascular risks of drugs such as Adderall, Ritalin, Concerta, Methylin and Metadate. ... - Austin American-Statesman (subscription),

Are ADHD Medications Safe Anymore?  Feb 10, 2006
...stimulants. The stimulants include: Ritalin, Concerta, Methylin, Metadate CD, and Adderall. The safety concerns relate to cardiac issues. ... - PR Web (press release),

Black Boxâ€? Warning Recommended For Psychiatry’s ADHD Drugs  Feb 11, 2006
...of the Vancouver chapter of the Citizens Commission on Human Rights stated, “Adderall, methylphenidates ( sold as Ritalin ), Concerta, Methylin and Metadate ... - I-Newswire.com (press release)

Midday Business Report: Missouri employers avoid cut in tax credit  09 Feb 2006
...hypertension. The drugs include amphetamines, such as Adderall, and methylphenidates, sold as Ritalin, Concerta, Methylin and Metadate. ... - Kansas City Star,

National news briefs  09 Feb 2006
...the drugs. which include amphetamines such as Adderall, and methylphenidates, sold as Ritalin, Concerta, Methylin and Metadate. - Concord Monitor,

World brief  09 Feb 2006
...potential cardiovascular risks of the drugs, which include amphetamines such as Adderall, and methylphenidates, sold as Ritalin, Concerta, Methylin and Metadate ... - Salem News,

ADHD Individual Drug Risk Studies To Be Considered By Drug Safety ...  Feb 8, 2006
...s Dexedrine and Dexedrine Spansules), methylphenidate (J&J’s Concerta, Novartis’ Ritalin, Ritalin SR, and Ritalin LA; Alliant’s Methylin and Methylin ER ... - FDA Advisory Committee

Forum Highlights Issues Teens Face  Dec 8, 2005
...cocaine. Ritalin, Methylin, Concerta and Provigil are all easy to obtain by teens because many teens are on these prescription pills. ... - Cheshire Herald,

Noven sinks on FDA feedback on ADHD patch  Dec 1, 2005
...higher doses. The drug is generally taken in pill form, marketed under such brand names as Ritalin, Methylin and Concerta. In the ... - MarketWatch

Shire/Noven Daytrana Side Effects Greater Than Concerta, FDA Says  Dec 1, 2005
...of other approved methylphenidate products.� Other methylphenidate products include Novartis’ Ritalin, UCB/Celltech’s Metadate, and Alliant’s Methylin. ... - FDA Advisory Committee

FDA reverses on Noven's ADHD drug  Dec 2, 2005
...higher doses. The drug has been marketed for years in pill form under such brand names as Ritalin, Methylin and Concerta. Noven ... - Investor's Business Daily (subscription)

Ritalin May Ease Hyperactivity In Autism-Related Disorders  Nov 9, 2005
Ritalin is also sold under the brand names Concerta, Metadate, and Methylin. The study was not supported by any of the drug-makers. - CNN

Consumers Union: ADHD Drugs Overprescribed  Sep 27, 2005
Consumer Reports names several forms of the stimulant methylphenidate as a best buy, including Metadate, Methylin, and generic forms of the drug. ... - WebMD

Study by Consumers Union Concludes ADHD Medications are Over ...  Sep 28, 2005
CU chose several forms of methylphenidate (the substance in the brand-name drug Ritalin) as a best buy, including Metadate, Methylin, and generic forms of the ... - Newsinferno.com,

Report names best-buy drugs for ADHD  Sep 28, 2005
Other forms include Celltech's Metadate, Alliant Pharmaceuticals' Methylin and generic forms of the drug methylphenidate, the report said. ... - United Press International

Alliant Pharmaceuticals to Conduct Largest US ADHD Clinical Survey  Aug 10, 2005
Launch of MOSAIC to evaluate convenience and compliance of Methylin (Methylphenidate HCL) Oral Solution ALPHARETTA, Ga., Aug. 10 ... - PR Newswire (press release),

Alliant Pharmaceuticals to Conduct Largest US ADHD Clinical Survey  Aug 10, 2005
...specialty pharmaceutical company, today announced its plans to sponsor the largest ADHD survey ever conducted in the US The survey, Methylin Oral Solution in ... - Yahoo News (press release) <**results**>

Dollars & Sense: A cure for high drug prices  Jun 22, 2005
The price for one drug, Methylin ER, a Ritalin generic, was $63.61, compared with $128.99 for 180 20-milligram pills at MedSave. ... - Minneapolis Star Tribune (subscription),

Dollars & Sense: A cure for high drug prices  Jun 22, 2005
The price for one drug, Methylin ER, a Ritalin generic, was $63.61, compared with $128.99 for 180 20-milligram pills at MedSave. ... - Minneapolis Star Tribune (subscription),

Ritalin may decrease the hypotensive effect of guanethidine. Use cautiously with pressor agents.

Human pharmacologic studies have shown that Ritalin may inhibit the metabolism of coumarin anticoagulants, anticonvulsants (phenobarbital, diphenylhydantoin, primidone), phenylbutazone, and tricyclic drugs (imipramine, clomipramine, desipramine). Downward dosage adjustments of these drugs may be required when given concomitantly with Ritalin.

Serious adverse events have been reported in concomitant use with clonidine, although no causality for the combination has been established. The safety of using methylphenidate in combination with clonidine or other centrally acting alpha-2 agonists has not been systemically evaluated.

 


Chemical IUPAC Name
methyl2-phenyl-2-(2-piperidyl)ethanoate

Chemical Formula
C14H19NO2

Half Life
2.4 hours in children and 2.1 hours in adults

Drug Type
Approved Drug

# Accession No
APRD00657

CAS Registry Number
113-45-1