Meclizine: profile and news

Renewed wet pattern will stick around Mar 2, 2006
...flying between SFO and Calgary, in spite of inflicting permanent damage to severely cramped passengers like himself, gulped a double dose of meclizine in order ... - St. Helena Star,

When Worlds Collide Feb 22, 2006
...home. The Martins say that after five months of treatment on meclizine, an antivertigo drug, their son is showing improvement. Mrs ... - LongIslandPress.com,

A crash course in cruising Jan 22, 2006
Bonine is just as effective and keeps you awake to enjoy some of that night life. Bonine also comes in a generic form called Meclizine NCL that is cheaper. ... - Indianapolis Star,

When choosing cruise line, learn to navigate info seas Jan 22, 2006
Bonine is just as effective and keeps you awake to enjoy some of that nightlife. Bonine also comes in a generic form called meclizine that is cheaper. ... - Jackson Clarion Ledger,

Cruise season is peaking Jan 22, 2006
...make you drowsy. Bonine is just as effective and it comes in a generic form called Meclizine NCL that is cheaper. If you prefer ... - Cincinnati Enquirer,

Claudication may require surgery Nov 29, 2005
...up. Dear Dr. Gott: My doctor prescribed meclizine for an 11-week bout of vertigo and Amoxil for an ear infection that followed. An ... - The Spokesman Review,

Trial begins against drug manager Nov 10, 2005
His chart showed markups of specific drugs, including a 2,200 percent markup for a generic motion sickness tablet called meclizine hydrochloride and a 300 ... - Cincinnati Enquirer,

Ramsay Hunt Syndrome Types I and II Sep 1, 2005
Corticosteroids such as prednisone may be used, and scopolamine or antihistamines such as meclizine (Antivert) will reduce vertigo and tinnitus. ... - rarediseases.about.com

Fluoxetine for Vestibular Dysfunction and Anxiety: A Prospective ... Jul 6, 2005
Medications such as meclizine may provide some initial relief but mask the ability of the central nervous system to compensate for the vestibular loss. ... - Psychosomatics (subscription)

Ramsay Hunt Syndrome Types I and II Jul 6, 2005
Corticosteroids such as prednisone may be used, and scopolamine or antihistamines such as meclizine (Antivert) will reduce vertigo and tinnitus. ... - rarediseases.about.com <**results**>

DEAR PHARMACIST Jun 28, 2005
...application to the scalp. MOTION SICKNESS: Bonine or Dramamine, look for active ingredient meclizine. COLD: Zicam medicated swabs ... - Newsday

Not Your "Typical Patient": Cryptococcal Meningitis in an ... Jun 11, 2005
...included a high- protein, high-calorie diet, dietician consultations, supplemental nutritional support, nausea medications such as meclizine 25 mg by mouth ... - RedNova.com

Ask the Pharmacist: Picking some of the top over-the-counter ... Jun 21, 2005
...important. RID Home Lice Control Spray is good. — Motion sickness: Bonine or Dramamine, look for active ingredient meclizine. — Cold ... - Marconews (subscription),

DR. HOOK- Shove boat: Patching together a cure Jun 9, 2005
There are other medicines for motion sickness, but they tend to be too sedating. Once I took Antivert (meclizine) in Maine when I went whale-watching. ... - The Hook,

Symptoms of Vertigo Apr 4, 2005
There are many drugs that will relieve a mild case of vertigo including perphenazine, scopolamine, meclizine and dimenhydrinate. ... - Khalsa News Network

Make your ride dizzy-free Apr 5, 2005
Take an over-the-counter antihistamine such as dimenhydrinate (Dramamine), meclizine (Antivert or Bonine) or diphenhydramine (Benadryl) before feeling sick. ... - Press-Enterprise (subscription)

Ramsay Hunt Syndrome Types I and II Apr 8, 2005
Corticosteroids such as prednisone may be used, and scopolamine or antihistamines such as meclizine (Antivert) will reduce vertigo and tinnitus. ... - rarediseases.about.com

Ramsay Hunt Syndrome Types I and II 08 Apr 2005
Corticosteroids such as prednisone may be used, and scopolamine or antihistamines such as meclizine (Antivert) will reduce vertigo and tinnitus. ... - rarediseases.about.com

Symptoms of Vertigo Apr 4, 2005
There are many drugs that will relieve a mild case of vertigo including perphenazine, scopolamine, meclizine and dimenhydrinate. ... - Khalsa News Network,

Other information

Indication
For the prevention and treatment of nausea, vomiting, or dizziness associated with motion sickness

Pharmacology
Meclizine, a piperazine-derivative H₁-receptor antagonist similar to buclizine, cyclizine, and hydroxyzine, is used as an antivertigo/antiemetic agent. Meclizine is used in the management of nausea, vomiting, and dizziness associated with motion sickness and vertigo in diseases affecting the vestibular apparatus.

Mechanism Of Action
Along with its actions as an antagonist at H₁-receptors, meclizine also possesses anticholinergic, central nervous system depressant, and local anesthetic effects. Meclizine depresses labyrinth excitability and vestibular stimulation and may affect the medullary chemoreceptor trigger zone.

Drug Category
Anti-allergic Agents; Antiemetics; Antihistamines;

Brand Names/Synonyms
Ancolan; Ancolon; Antivert; Antivert/25; Antivert/50; Bonadettes; Bonadoxin; Bonamine; Bonine; Calmonal; Chiclida; Diadril; Dramamine; Dramamine Ii; Histamethine; Histamethizine; Histametizine; Histametizyne; Itinerol; Longifene; Marex; Meclicot; Meclizine; Meclizine Hcl; Meclozine; Medivert; Monamine; Navicalm; Neo-Istafene; Neo-Suprimal; Neo-Suprimel; Parachloramine; Peremesin; Postafen; Postafene; Ravelon; Sabari; Sea-Legs; Siguran; Subari; Suprimal; Travelon; U. C. B. 5062; UCB 170; UCB 5052; UCB 5062; Veritab; Vibazine; Vomisseis; Vomissels

Dosage Forms
Tablets

Absorption
Well absorbed

Interactions
Interactions for Meclizine:

No information provided.

Chemical IUPAC Name
1-[(4-chlorophenyl)-phenyl-methyl]-4-[(3-methylphenyl)methyl]piperazine

Chemical Formula
C25H27ClN2

Half Life
6 hours

Drug Type
Approved Drug

# Accession No
APRD00354

CAS Registry Number
569-65-3