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Maxipime: profile and news
Elan Shares Discounting $1.2B Tysabri Sales Feb 1, 2006 Losses at Elan improve to $384m and shares rise Jan 31, 2006 Europe: Telephone stocks fall as executives resign Feb 1, 2006 Elan meldt financiële resultaten vierde kwartaal en hele jaar ... Jan 31, 2006 Elan Shares Discounting $1.2B Tysabri Sales Feb 1, 2006 Loss Narrows for Elan Jan 31, 2006 Losses at Elan improve to $384m and shares rise Jan 31, 2006 UK Telephone Stocks Fall, Led by Cable & Wireless; Elan Gains Jan 31, 2006 European Phone Stocks Drop, Led by Cable & Wireless; BASF Gains Jan 31, 2006 Europe: Telephone stocks fall as executives resign Feb 1, 2006 Elan 'optimistic' on Tysabri return, earmarks cash for relaunch ... Jan 31, 2006 Elan cuts losses; earmarks funds for Tysabri return Jan 31, 2006 CareNet Offering Information on Daiichi Pharmaceutical's Sunrhythm ... Nov 25, 2005 Elan Reports Third Quarter 2005 Financial Results Oct 26, 2005 Elan Reports Third Quarter 2005 Financial Results Oct 27, 2005 Elan Reports Narrowed Loss Oct 27, 2005 Elan cuts losses by 38pc in Q3 Oct 27, 2005 Elan pain drug sells below expectations Oct 29, 2005 Elan Reports Second Quarter 2005 Financial Results Jul 27, 2005 Elan shares plunge after death linked to top drug Apr 1, 2005 Tysabri's woes weigh heaviest on Elan Mar 31, 2005 Firms hoped to expand sales for multiple sclerosis drugs Mar 4, 2005 Biogen/Elan's Tysabri adds pressure on FDA Mar 6, 2005 Other information Indication For the treatment of the following infections (respiratory, skin, soft tissue, urinary tract infections, ear, nose, throat infectsion) caused by; S. pneumoniae, H. influenzae, staphylococci, S. pyogenes (group A ß-hemolytic streptococci), E. coli, P. mirabilis, Klebsiella sp, coagulase-negative staph. Also used to treat acute bacterial bronchitis in patients with COPD Pharmacology Cefuroxime, a second-generation cephalosporin, is used to treat severe upper and lower respiratory tract infections, skin infections, otitis media, and surgical prophylaxis. Mechanism Of Action Cefuroxime, like the penicillins, is a beta-lactam antibiotic. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that cefuroxime interferes with an autolysin inhibitor. Drug Category Anti-bacterial Agents; Cephalosporins; ATC:J01DC02 Brand Names/Synonyms Ancef; Biofuroksym; Ceclor; Ceclor Cd; Cedax; Cefditoren; Cefizox; Cefotan; Ceftin; Ceftizoxime Sodium; Cefurax; Cefuril; Cefuroxim; Cefuroxime; Cefuroxime Axetil; Cefuroxime Free Acid; Cefuroxime Sodium; Cefuroxime Sodium Salt; Cefuroxime [Usan:Ban:Inn]; Cefuroxime and Dextrose in Duplex Container; Cefuroximo [Inn-Spanish]; Cefuroximum [Inn-Latin]; Cefzil; Cephuroxime; Ceptaz; Duricef; Elobact; Fortaz; Keflex; Keftab; Kefurox; Kefurox in Plastic Container; Kerurox; Mandol; Maxipime; Mefoxin; Monocid; Omnicef; Oraxim; Rocephin; Sharox; Tazicef; Vantin; Velosef; Zinacef; Zinacef Danmark; Zinacef in Plastic Container; Zinat; Zinnat Dosage Forms POWDER; POWDER FOR SOLUTION; TABLET Absorption Well absorbed from the GI tract (bioavailability is 37-52%) Interactions -->Interactions for Cefuroxime: Drug/Laboratory Test Interactions: A false-positive reaction for glucose in the urine may occur with copper reduction tests (Benedictís or Fehlingís solution or with ClinitestÒ tablets) but not with enzyme-based tests for glycosuria. As a false-negative result may occur in the ferricyanide test, it is recommended that either the glucose oxidase or hexokinase method be used to determine blood plasma glucose levels in patients receiving cefuroxime. Cefuroxime does not interfere with the assay of serum and urine creatinine by the alkaline picrate method. Chemical IUPAC Name 4-(carbamoyloxymethyl)-8-[2-(2-furyl)-2-methoxyimino-acetyl]amino-7-oxo-2-thia-6-azabicyclo[4.2.0]oct-4-ene-5-carboxylic acid Chemical Formula C16H16N4O8S Half Life ~80 minutes Drug Type Approved Drug # Accession No APRD00285 CAS Registry Number 55268-75-2 |
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