Lopressor: profile and news






Cyclists have rights on roads  Dec 5, 2005
Mr. Melton should take a Lopressor for his blood pressure and leave for work earlier, because believe you me, when I start riding when the weather gets warmer ... - News-Leader.com,

Beta blockers make golfers 'just blah'  Nov 28, 2005
The drugs, which are sold under brand names such as Tenormin and Lopressor, are prescribed to treat high blood pressure, heart arrhythmia and glaucoma, among ... - ESPN

SUSAN TOMPOR: Drug plans a maze, so here's some help  Nov 14, 2005
..."Everybody's telling me I better sign up," Romstad said. One drug, Lopressor, which is used to treat hypertension, costs her $200 for a 90-day supply. ... - Detroit Free Press,

Warning about drug mix-ups  Sep 29, 2005
The three drugs are: Toprol-XL, also known as metoprolol succinate (the South African trade name is Lopressor); Topamax, also known as topiramate; and Tegretol ... - Health24.com,

Warning about drug mix-ups  Sep 29, 2005
The three drugs are: Toprol-XL, also known as metoprolol succinate (the South African trade name is Lopressor); Topamax, also known as topiramate; and Tegretol ... - Health24.com,

Diagnosing heart disease ... maybe  Jul 6, 2005
I had to go to his office at dawn so I could take Lopressor, a standard beta blocker, and wait for my heart rate to drift down from its normal 72 beats a ... - International Herald Tribune <**results**>

Diagnosing heart disease ... maybe  Jul 6, 2005
I had to go to his office at dawn so I could take Lopressor, a standard beta blocker, and wait for my heart rate to drift down from its normal 72 beats a ... - International Herald Tribune,

Alice Heckman  Apr 24, 2005
...(4) Lopressor, Toprol, metoprolol. Beta blocker that treats high blood pressure and prevents chest pain called angina. (5) Prinivil, Zestril, lisinopril. ... - Kentucky.com

Daily drug regimen of Alice and Ken Heckman  Apr 16, 2005
3) Glucotrol, glipizide. Another diabetes drug that stimulates the pancreas to release more insulin. 4) Lopressor, Toprol, metoprolol. ... - New York Newsday

Online drug bust is casting a wide net  Apr 22, 2005
Nina said she lost her health insurance last year and could not afford a doctor's visit to get a prescription for her blood-pressure medicine, Lopressor. ... - Philadelphia Inquirer,

Drug tests of convict sought  Feb 19, 2005
Goepp, who lost his medical license after pleading guilty last year to the child porn charges, tried to obtain the blood pressure medication, Lopressor, in the ... - Rochester Democrat and Chronicle,

Report: Plavix key in heart attack care:  Mar 10, 2005
The study also established giving the beta-blocker metoprolol, known as Lopressor or Toprol, as an emergency treatment for heart attacks cuts the risks of ... - New Kerala,

Generic Drugs - Original Medicinal Drugs  Feb 25, 2005
In most cases the trade name will indicate a particular characteristic of the drug such as Lopressor which lowers blood pressure. ... - Express Newsline,

BCBSNC Launches New Prescription Drug Savings Initiative  Feb 17, 2005
Drugs to Treat High Blood Pressure) atenolol (generic Tenormin) labetalol (generic Trandate, Normodyne) metoprolol (generic Lopressor) nadolol (generic Corgard ... - PR Newswire (press release)

Heart Attack Care May Be Worse for Women  Feb 21, 2005
...than men to be treated with cholesterol-lowering drugs, such as Zocor and Lipitor, but less likely to receive beta-blockers, such as Lopressor and Inderal ... - Reuters

Update on Risk Factors for Atherosclerosis: The Role of ...  Feb 26, 2005
For example, beta blockers, such as metoprolol (Lopressor), atenolol (Tenormin), and propanolol (Inderal) increase plasma triglycerides and decrease HDL ... - RedNova.com,

Management of Hypertension in Older Persons  Feb 21, 2005
Atenolol (Tenormin), bisoprolol (Zebeta), and metoprolol (Lopressor, Toprol XL) are cardioselective beta blockers with low lipid solubility, and therefore have ... - RedNova.com,


Other information


Indication
For the treatment of hypertension and angina pectoris

Pharmacology
Metoprolol, a competitive, beta1-selective (cardioselective) adrenergic antagonist, is similar to atenolol in its moderate lipid solubility, lack of intrinsic sympathomimetic activity (ISA), and weak membrane stabilizing activity (MSA).

Mechanism Of Action
Like betaxolol and atenolol, metoprolol competes with adrenergic neurotransmitters such as catecholamines for binding at beta(1)-adrenergic receptors in the heart and vascular smooth muscle. Beta(1)-receptor blockade results in a decrease in heart rate, cardiac output, and blood pressure.

Drug Category
Sympatholytics; Antihypertensive Agents; Antiarrhythmic Agents; Adrenergic Agents; ATC:C07AB02; ATC:C07AB52

Brand Names/Synonyms
Beloc; Betaloc; CGP 2175; H 93/26; H-23/96; LOPRESSOR HCT; Lopresor; Lopresoretic; Lopressor; Metoprolol; Metoprolol Tartrate; Metroprolol; Prelis; Selo-Zok; Seloken; Selopral; Toprol; Toprol-Xl

Dosage Forms
Tablets

Absorption
rapid and complete, 50%

Interactions
Interactions for Metoprolol:

Catecholamine-depleting drugs (e.g., reserpine) may have an additive effect when given with beta-blocking agents. Patients treated with extended release metoprolol succinate plus a catecholamine depletor should therefore be closely observed for evidence of hypotension or marked bradycardia, which may produce vertigo, syncope, or postural hypotension.



Chemical IUPAC Name
1-[4-(2-methoxyethyl)phenoxy]-3-(1-methylethylamino)propan-2-ol

Chemical Formula
C15H25NO3

Half Life
3-7 hours

Drug Type
Approved Drug

# Accession No
APRD00208

CAS Registry Number
37350-58-6

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