Linezolid: profile and news

It starts skin deep, and then . . . Mar 1, 2006
There is a hierarchy of antibiotics, starting with weaker drugs such as penicillin and working up to the strongest, including vancomycin and linezolid. ... - Chicago Tribune,

Scientists re-engineer antibiotic to counter drug resistance Feb 9, 2006
The product, tigecycline (Tygacil) joins the oxazolidinones, (Pfizer's linezolid) and lipopeptides (Cubist's daptomycin) in a small but growing arsenal against ... - DrugResearcher.com,

Genomics in Antibacterial Drug Discovery Feb 7, 2006
Development of resistance to every class of antibiotic, including the recently marketed Zyvox (linezolid) from Pfizer, is seriously limiting antibiotic options ... - Drug Discovery & Development (subscription),

Scientists re-engineer antibiotic to counter drug resistance 09 Feb 2006
The product, tigecycline (Tygacil) joins the oxazolidinones, (Pfizer's linezolid) and lipopeptides (Cubist's daptomycin) in a small but growing arsenal against ... - DrugResearcher.com,

With Many Big Pharma Companies Recently Choosing to Withdraw From ... Jan 26, 2006
With the availability of several products active against MRSA and VRE (eg, linezolid (Pfizer's Zyvox), daptomycin (Cubist's Cubicin)), the most significant ... - Genetic Engineering News,

Malaria, AIDS, Avian Flu, and MRSA-will we survive? Jan 19, 2006
...develop a new antibiotic. In the year 2000, $800 million was spent developing the last new antibiotic, Linezolid. Within only twelve ... - IPP Media - Guardian,

Chiron wins EU approval for IV antibiotic Jan 24, 2006
The others are Pfizer's Zyvox (linezolid) and Sanofi-Aventis' Ketek (telithromycin; which hit the headlines itself yesterday after being linked to liver ... - Pharma Times (subscription),

The Doctor's Choice Awards Dec 9, 2005
Pfizer also walked away with three honors—two for Zyvox (linezolid) and another for Spiriva (tiotropium), which it jointly markets with Boehringer Ingelheim. ... - Medgadget.com,

The Market for Antibacterials, Valued at $24 Billion in the Seven ... Nov 15, 2005
Rapid uptake of products focused on drug-resistant infections, such as Pfizer's Zyvox (linezolid), has been driven by the increasing numbers of ... - Genetic Engineering News,

Avian flu threat real, but staph infection here now Nov 15, 2005
After that, the only MRSA drug available is costly linezolid (Zyvox), which physicians consider the gold standard for Vanco-resistant MRSA. ... - Buffalo News,

Cubist: more good news for superbug drug Nov 24, 2005
The most successful new drug launched in the past few years for the treatment of MRSA infections has been Pfizer's Zyvox (linezolid). ... - Pharmaceutical Business Review

First Reported Hospital Outbreak of Linezolid-Resistant ... Oct 11, 2005
By Rabiya Tuma. SAN FRANCISCO, CA -- October 11, 2005 -- Fifteen patients were diagnosed with linezolid-resistant enterococcus in a Tennessee hospital. ... - DG News

Linezolid Outpatient Treatment Costs Less than Intravenous ... Oct 11, 2005
SAN FRANCISCO, CA -- October 11, 2005 -- Oral linezolid costs more, but outpatient treatment with this drug over 35 days actually costs an average of $4,600 US ... - DG News

IDSA: First Reported Hospital Outbreak of Zyvox (linezolid) ... Oct 10, 2005
10 - In the first reported hospital outbreak of Zyvox (linezolid)-resistant enterococcus, only half the infected patients had a history of Zyvox exposure ... - MedPage Today,

Oral use of ZYVOX (Linezolid) is better to Intravenous Vancomycin ... Oct 9, 2005
The results show that oral tablets of Linezolid (ZYVOX), provides better treatment and significant savings of money spent to health clinics compared to ... - MedIndia,

Oral linezolid cost effective for outpatient treatment of skin ... Oct 7, 2005
ZYVOX formulations are contraindicated for use in patients who have known hypersensitivity to linezolid or any of the other product components. ... - RxPG NEWS,

Oral ZYVOX(r) Shows Cost Savings for Treatment of Skin Infections Oct 7, 2005
Newswise — Oral ZYVOX® (linezolid) was associated with significant savings to the health care system – an average of $4,630 per patient – compared to ... - Newswise (press release)

Oral ZYVOX® shows cost savings for outpatient treatment of skin ... Oct 7, 2005
SAN FRANCISCO, October 7, 2005 – Oral ZYVOX® (linezolid) was associated with significant savings to the health care system – an average of $4,630 per ... - EurekAlert (press release),

New Life and CureLab id anti-fungal compound Oct 18, 2005
Of this, drugs such as Vancomycin, Linezolid and other such anti-infectives used in treating resistant strains of bacteria constitute nearly $1 billion. ... - Drug Researcher.com,

New Class Of Antibiotics Effective Against Drug-resistant Bacteria ... Oct 17, 2005
Linezolid Is Highly Effective Against Antibiotic-Resistant Infections (August 17, 1999) -- A study by researchers at Northwestern University Medical School and ... - Science Daily (press release)

Dallas Biotech Attracts Pharmaceutical Veteran Oct 24, 2005
He served as the clinical program leader for linezolid and therapeutic area head for anti-infective research at the Pharmacia Corporation and the director of ... - Business Wire (press release),

Researchers Identify New Topical Antibiotic that May Inhibit ... Oct 24, 2005
...in treating all isolates of S. aureus, even strains resistant to other antibiotic treatments such as methicillin, mupirocin, vancomycin, and linezolid. ... - Newsinferno.com,

Growing Antibacterial Resistance Set to put Antibiotic R&D Back in ... Oct 19, 2005
The product, tigecycline (Tygacil) joins the oxazolidinones (Pfizer's linezolid) and lipopeptides (Cubist's daptomycin) in a small but growing arsenal against ... - Canada NewsWire (press release),

High Rate of Methicillin-resistant Staphylococcus Infection Seen ... Oct 11, 2005
In two of the studies in which it was compared with either linezolid or vancomycin, dalbavancin demonstrated high rates of efficacy against MRSA. ... - DG News

Tips from the Journals of the American Society for Microbiology Oct 20, 2005
Researchers found all isolates of S. aureus, including strains resistant to methicillin, mupirocin, vancomycin, and linezolid, to be susceptible to REP8339 as ... - EurekAlert (press release),

Fresh from the pipeline: Tigecycline Oct 5, 2005
Furthermore, agents in completely new classes have been very rare; only two such antibiotics, linezolid (Zyvox; Pfizer) and daptomycin (Cubicin; Cubist), have ... - Nature.com (subscription),

First Reported Hospital Outbreak of Linezolid-Resistant ... 11 Oct 2005
By Rabiya Tuma. SAN FRANCISCO, CA -- October 11, 2005 -- Fifteen patients were diagnosed with linezolid-resistant enterococcus in a Tennessee hospital. ... - DG News

High Rate of Methicillin-resistant Staphylococcus Infection Seen ... 11 Oct 2005
In two of the studies in which it was compared with either linezolid or vancomycin, dalbavancin demonstrated high rates of efficacy against MRSA. ... - DG News

Reducing Antibiotic Use Lowers Rates Of Drug-resistant Bacteria Sep 2, 2005
Linezolid Is Highly Effective Against Antibiotic-Resistant Infections (August 17, 1999) -- A study by researchers at Northwestern University Medical School and ... - Science Daily (press release)

First annual mandatory surveillance data published on clostridium ... Sep 3, 2005
...in the range of antibiotics which are effective against them. Antibiotics linezolid and synercid are usually used in treatment. - Medical News Today (press release),

Research and Markets: Antibacterials - Pharma Strikes Antibac Aug 17, 2005
Rapid uptake of products focused on drug-resistant infections, such as Pfizer's Zyvox (linezolid), has been driven by the increasing numbers of ... - Business Wire (press release),

Coagulase-Negative Staphylococcus within Neutrophils in Acute ... Aug 24, 2005
Teicoplanin was changed to linezolid. By day 37, the fever had resolved. However, refractory multiorgan failure developed, and the patient died on day 49. - New England Journal of Medicine (subscription),

Diabetic Nerve Therapy Shows 'Striking' Results Aug 17, 2005
Antibiotic Effective For Diabetic Foot Infections (January 19, 2004) -- A clinical trial involving 371 patients in eight countries shows that linezolid, a new ... - Science Daily (press release)

Antibacterial hope lies in clever drugs for superbugs Aug 19, 2005
Indeed, recent drug launches including King Pharmaceuticals' Synercid (quinupristin/dalfopristin) in 1999, Pfizer's Zyxox (linezolid) in 2000 and Cubist's ... - Pharmaceutical Business Review

FDA Sends Letter to Pfizer Over Zyvox Advertisement Jul 26, 2005
...of Drug Marketing, Advertising, and Communications (DDMAC) has reviewed a professional journal advertisement (ad) for ZYVOX® (linezolid) injection, tablets ... - PharmaLive.com (press release)

Commercial Insight: Antibacterials - Pharma Strikes Antibac Aug 2, 2005
Rapid uptake of products focused on drug-resistant infections, such as Pfizer's Zyvox (linezolid), has been driven by the increasing numbers of ... - Pharmaceutical Business Review

Bacterial Cooperation As A Target For Anti-infectious Therapy Jul 25, 2005
Linezolid Is Highly Effective Against Antibiotic-Resistant Infections (August 17, 1999) -- A study by researchers at Northwestern University Medical School and ... - Science Daily (press release)

US FDA Warns Pfizer Over Ad for Antibiotic Drug Jul 26, 2005
...about "misleading promotion" of its antibiotic drug Zyvox (linezolid) in a professional journal, according to a letter released on Tuesday. ... - Medscape (subscription)

Community-Acquired MRSA: Evolving Pathogens Jul 13, 2005
...that most of the CA-MRSA isolates are susceptible to vancomycin, gentamicin, rifampin, trimethoprim-sulfamethoxazole, clindamycin, doxycycline, and linezolid. ... - Medscape (subscription)