Lamisil: profile and news

FUNGAL LUNG INFECTION PRODUCES BLOODY SPUTUM  Feb 7, 2006
There is no good reason to do so, however. DEAR DR. DONOHUE: Some weeks ago, you wrote that Lamisil cream or ointment is a treatment for toenail fungus. ... - Charlotte Sun-Herald,

Pacific Biometrics Names New Business Development Manager  Feb 27, 2006
...the Company, Mr. Jackle was District Manager of Novartis Pharmaceuticals, where he facilitated seven promotions, including Elidel and Lamisil, which were first ... - Genetic Engineering News,

Novartis: Strengthening Its Infectious Disease Portfolio  Feb 9, 2006
Novartis' ID portfolio consists of antivirals, including Famvir (famciclovir) and Denavir (penciclovir), and antifungals, specifically Lamisil (terbinafine). ... - International News Service,

Tacky marquee doesn't enhance venerable Morris theater  Feb 5, 2006
...initial problem. An example of this is the drug Lamisil that is used for nail fungus. This drug is damaging to the liver. A person ... - South Bend Tribune,

Super Bowl Pedicure: It's not as bad as being stabbed in a knife ...  Feb 6, 2006
...is. "Kelso, what's wrong with that toenail? It looks like the commercial for Lamisil with the little bugs," she said. Listen kid ... - Austin American-Statesman (subscription),

Kelso: Will I lose Bubba credentials over a pedicure?  09 Feb 2006
...is. "Kelso, what's wrong with that toenail? It looks like the commercial for Lamisil with the little bugs," she said. Listen, kid ... - Waco Tribune Herald,

FUNGAL LUNG INFECTION PRODUCES BLOODY SPUTUM  Feb 7, 2006
There is no good reason to do so, however. DEAR DR. DONOHUE: Some weeks ago, you wrote that Lamisil cream or ointment is a treatment for toenail fungus. ... - Charlotte Sun-Herald,

Sankyo Releases Lamisil AT in New Female-Friendly Pink Packaging  Jan 26, 2006
26, 2006 – Sankyo Co., Ltd., a subsidiary of DAIICHI SANKYO COMPANY, LIMITED, has announced the release of Lamisil AT® series athlete’s foot medication in ... - PharmaLive.com (press release),

Novartis Profit Growth Stalls as Lamisil Sales Fall (Update6)  Jan 19, 2006
AG, Switzerland's largest drugmaker, said fourth-quarter earnings growth stalled and revenue missed analysts estimates as sales of the Lamisil fungal treatment ... - Bloomberg

Novartis: strengthening its infectious disease portfolio  Feb 7, 2006
Novartis' ID portfolio consists of antivirals, including Famvir (famciclovir) and Denavir (penciclovir), and antifungals, specifically Lamisil (terbinafine). ... - Pharmaceutical Business Review

Common fungus, uncommon reaction  Jan 30, 2006
Q: Some weeks ago, you wrote that Lamisil cream or ointment is a treatment for toenail fungus. ... A The Lamisil item was a long-winded bit about toenail fungus. ... - Contra Costa Times,

Antifungal foot cream blamed for renal failure  Jan 19, 2006
10 seeks damages in excess of $150,000. Kamadulski claims she asked her doctor for a Lamisil prescription to treat a toenail fungal infection on Jan. ... - Madison County Record,

Super Bowl Pedicure: It's not as bad as being stabbed in a knife ...  Feb 6, 2006
...is. "Kelso, what's wrong with that toenail? It looks like the commercial for Lamisil with the little bugs," she said. Listen kid ... - Austin American-Statesman (subscription),

Connetics Reports Fourth Quarter Revenues of $41.3 Million and EPS ...  Jan 31, 2006
Novartis launched a new formulation of single-dose Lamisil(R) (terbinafine hydrochloride) in Europe using Connetics' Liquipatch(TM) sustained-release gel ... - Genetic Engineering News,

Novartis 4th-Qtr Net Unchanged; Shares Tumble (Update6)  Jan 19, 2006
AG, Switzerland's largest drugmaker, said fourth-quarter earnings growth stalled and revenue missed analysts estimates as sales of the Lamisil fungus treatment ... - Bloomberg

Tacky marquee doesn't enhance venerable Morris theater  Feb 5, 2006
...initial problem. An example of this is the drug Lamisil that is used for nail fungus. This drug is damaging to the liver. A person ... - South Bend Tribune,

Drug manufacturers find portfolios age and shrink in sales value  Jan 20, 2006
Novartis reported earnings unchanged at $1.35 billion, but sales rose less than forecast; revenue from the companys angifungal drug Lamisil fell 17 percent. - Manufacturer.com,

Novartis shakes up agency roster  Jan 24, 2006
Saatchi & Saatchi has won the global brief for painkiller Voltarol, Nicotinell will remain with Euro RSCG and Grey will handle athlete's foot product Lamisil. - DM Bulletin,

(PZ) Novartis Delivers Strong Performance with Record Results in ...  Jan 18, 2006
2% in USD but rose 6% in local currencies based on good performances from Diovan and Glivec, which offset the impact of generic versions of Lamisil and Foradil ... - Houston Chronicle,

Health | What’s in a name?  Jan 26, 2006
This year, for example, patents will expire on the drugs Lamisil (an antifungal), Zoloft (which treats depression and anxiety) and Altace (for high blood ... - The State,

Hair loss among women has many causes  Jan 27, 2006
It is annoying but harmless. There are several effective over-the-counter remedies, including Tinactin, Desenex and Lamisil. If ... - Monterey County Herald,

Pfizer Fourth-Quarter Net Falls 3 Percent; Lipitor Sales Slow  Jan 19, 2006
Novartis AG, Europe's second-largest drugmaker, said fourth- quarter earnings growth stalled as the Lamisil fungus treatment fell and the consumer unit ... - Bloomberg

Pfizer, Novartis Profits Stall as Older Drugs Slow (Update1)  Jan 19, 2006
Revenue from Novartis's Lamisil fungus drug fell 17 percent. Lipitor sales rose 3 percent, down from 23 percent a year earlier. ... - Bloomberg

Novartis 4th-Quarter Net Unchanged on Higher Costs (Update3)  Jan 19, 2006
...quarter. Revenue from the fungal treatment Lamisil fell 17 percent, while sales of the transplant drug Neoral declined 10 percent. ... - Bloomberg

Earnings stall for Pfizer and Novartis  Jan 20, 2006
Sales of Pfizer's Lipitor rose 3 percent, down from a 23 percent gain a year earlier, and revenue from Novartis's antifungal drug, Lamisil, was down 17 percent ... - International Herald Tribune,

A Germ of an Idea  Jan 16, 2006
...an unpleasant fellow who was vanquished by Sanka decaffeinated coffee; Digger the Dermatophyte, representing the fungal condition fought by Lamisil; and the ... - New York Times,

Slow demand weighs down Pfizer, Novartis  Jan 20, 2006
...lower revenue because of generic competition. Revenue from Novartis's Lamisil fungus drug fell 17 per cent. Lipitor sales rose 3 per ... - Globe and Mail,

Pfizer, Novartis report lackluster earnings  Jan 20, 2006
...competition. Revenue from Novartis' Lamisil fungus drug fell 17 percent. Lipitor sales rose 3 percent, down from 23 percent a year earlier. ... - Sun-Sentinel.com,

The creepy new ad for Theraflu.  Jan 23, 2006
In 2003, Brendan I. Koerner explained the difference between outbreaks and epidemics. Also in 2003, Rob Walker reacted with horror to an unpleasant Lamisil ad. ... - Slate

Athlete’s foot could require more treatment  12 Dec 2005
...or sprays. The most commonly used prescription medications are clotrimazole (Lotrimin) and terbinafine (Lamisil AT). With topical ... - Fort Wayne Journal Gazette,

Mr. Thomas's book declares war on toenail fungus  Nov 21, 2005
Not really. Only a few new and costly prescription drugs -- Lamisil and Penlac are two big ones -- have proven ability to penetrate a toenail. ... - Pittsburgh Post Gazette,

Twitches could be neurological disorder  Nov 25, 2005
I went to a podiatrist in July of that year; he did not take a culture and prescribed Lamisil, which I took for approximately six months. ... - Monterey County Herald,

Kline Study Predicts RX-to-OTC Switches For Antifungal Medications  Nov 17, 2005
Products such as Novartis' Lamisil have moderate chances of switching in Germany, where the Rx patent is set to expire in 2006, Mahecha says. ... - PR Newswire (press release),

Toenail fungus warrants author 'memoir'  Nov 22, 2005
Dwight Thomas, 60, of Savannah, Ga., concludes a combination of Lamisil and Penlac works best in his "The War Against Toenail Fungus.". ... - United Press International

Health Notes  Nov 22, 2005
...about 35 million people nationally have toenail fungus and spend about $1 billion a year on treatments, including the prescription drugs Lamisil and Penlac. ... - Savannah Morning News,

Pharma Reformulates  Dec 5, 2005
US exclusivity: Zoloft, Merck's Zocor, Sanofi-Aventis' hypnotic Ambien, BMS's Pravachol (licensed from Daiichi Sankyo), Novartis' antifungal Lamisil, and GSK's ... - Chemical & Engineering News

Treating nails when fungus, yeast invade  Nov 8, 2005
The two most common are Lamisil and Sporanox. Both are taken orally, usually for several months. ... It is definitely not good to mix caffeine with Lamisil! ... - Newsday,

POLYMYALGIA CAUSES MUSCLE SORENESS IN OLDER PEOPLE  Nov 9, 2005
If it doesn't work, there are backup medicines. Sporanox and Lamisil are two oral medicines that are quite effective in eliminating toe- and fingernail fungus. ... - Charlotte Sun-Herald,

Moving toward safe health care  Nov 9, 2005
...names. Take for example Lamictal (antiepileptic), Lamisil (antifungal) Ludiomil (antidepressant) and Lomotil (antidiarrheic). More ... - Naples Sun Times,

New law aims to cure doctors' bad habit  Oct 30, 2005
But Lamictal, an anti-epileptic, remains Lamictal, despite its superficial similarity with Lamisil, an antifungal used to treat athletes foot and other skin ... - The Casper Star Tribune,

Back to life  Oct 20, 2005
Novartis repositioned Lamisil in 2001 with a new campaign, and in doing so, changed physicians’ perception of toenail fungus from mere cosmetic annoyance to ... - Med Ad News (subscription),

Wockhardt Q3 net vaults 17% to Rs 65 crore  Oct 19, 2005
During the quarter, Wockhardt UK launched a new generic product - antifungal drug terbenafine - on the first day of the brand (Lamisil) going off patent. ... - Economic Times,

Misinformation About Toenail and Foot Health Are Abundant, Survey ...  Oct 3, 2005
Lamisil Tablets are a highly effective treatment for mild to severe fungal nail infection and are the most prescribed treatment for fungal nail infection ... - PR Newswire (press release),

Global Drug Sales May Rise 7% in 2006 to $650 Billion (Correct)  Oct 25, 2005
...competition in key markets next year include Pfizer Inc.'s Zoloft antidepressant, Sanofi Aventis SA's Ambien for insomnia, Novartis AG's Lamisil for nail ... - Bloomberg

Strategist spots Novartis, Statoil ASA  Oct 26, 2005
Unlike some of its Big Pharma rivals, Novartis faces only one patent expiration -- for antifungal agent Lamisil -- in the remainder of this decade, Barron's ... - MSN Money

Novartis delivers strong growth in first nine months of 2005 on ...  Oct 18, 2005
Lamisil (USD 318 million) (-8% worldwide; -7% lc; -1% US), the leading treatment worldwide for fungal nail infections, posted modest decline in sales following ... - Biotech Intelligence (press release),

TREATMENT FOR DIARRHEA HINGES ON FINDING ITS CAUSE  Oct 13, 2005
In some, it itches. Tinea versicolor can usually be treated with a number of antifungal medicines, including Lamisil cream or selenium-sulfide lotion. ... - Charlotte Sun-Herald,

On the Importance of Staying Abreast of One’s Health  Oct 15, 2005
...cancer demons inside me — and on micro-luminescence they would surely snarl and snicker like those fiendish dermatophytes in the Lamisil (toenail fungus) TV ... - The Signal,

More pharma patent litigations in store — Ranbaxy, Dr Reddy's ...  Oct 17, 2005
So, even if Pfizer has been able to get the upper hand in the UK litigation and Novartis having gained on its anti-fungal drug Lamisil, Ranbaxy and DRL too ... - Hindu Business Line,

Drug firms shrug off patent setbacks  Oct 16, 2005
...industry. Dr Reddy’s lost two cases last year — one is over Lamisil against Novartis and other over Norvasc against Pfizer. ... - Calcutta Telegraph,

State law takes aim at docs' bad writing  Oct 22, 2005
...said. Or imagine the patient who gets Lamisil, an anti-fungal medication, instead of Lamictal, a mood stabilizer and anti-epileptic. ... - Billings Gazette,

DTC Redefined  Oct 20, 2005
An example of the gratuitous ads that focus on cosmetic conditions, Arxcel cites the "Digger" promotion for the toenail fungus drug Lamisil. ... - Med Ad News (subscription),

Your 12 Most Embarrassing Beauty Questions -- Answered  Oct 3, 2005
The fix:The most effective treatment is a prescription antifungal pill like Lamisil or Sporanox, but be warned: These treatments are only 70 to 80 percent ... - More TV 32.com,

Misinformation About Toenail and Foot Health Are Abundant, Survey ...  Oct 3, 2005
Lamisil Tablets are a highly effective treatment for mild to severe fungal nail infection and are the most prescribed treatment for fungal nail infection ... - PR Newswire (press release),

Novartis Signs Global Licensing Agreement to Develop New Topical ...  Sep 15, 2005
...agreement with NexMed, Inc (NASDAQ: NEXM) to develop new topical forms of terbinafine, the active ingredient in its popular Lamisil® (terbinafine tablets ... - PharmaLive.com (press release),

NexMed licenses drug to Novartis  Sep 15, 2005
...the topical treatment -- a coating that is brushed onto the infected area -- left substantially less drug in the bloodstream than Novartis' Lamisil tablet. ... - BusinessWeek

Your 12 Most Embarrassing Beauty Questions -- Answered  Oct 4, 2005
The fix:The most effective treatment is a prescription antifungal pill like Lamisil or Sporanox, but be warned: These treatments are only 70 to 80 percent ... - Jackson Channel.com,

Novartis, NexMed sign nail fungus licensing deal  Sep 15, 2005
...said it has signed a global licensing agreement with NexMed Inc to develop new topical forms of terbinafine, the active ingredient in its Lamisil treatment for ... - Forbes

Should You Always Tell the Truth?  Sep 12, 2005
Also, I have a fungus on my toenails and am taking Lamisil.� Or, “I have been victimized in two bad relationships that have left me feeling cold ... - Bella Online

NexMed Signs Global Licensing Agreement for Its Proprietary Anti ...  Sep 14, 2005
...anti-fungal lacquer NM100060 incorporates NexACT penetration enhancers with terbinafine, the active ingredient in Novartis' blockbuster anti-fungal drug Lamisil ... - Yahoo! News (press release)

In vitro studies with human liver microsomes showed that terbinafine does not inhibit the metabolism of tolbutamide, ethinylestradiol, ethoxycoumarin, and cyclosporine. In vitro studies have also shown that terbinafine inhibits CYP2D6-mediated metabolism. This may be of clinical relevance for compounds predominantly metabolized by this enzyme, such as tricyclic antidepressants, ß-blockers, selective serotonin reuptake inhibitors (SSRIs), and monoamine oxidase inhibitors (MAO-Is) Type B, if they have a narrow therapeutic window.

In vivo drug-drug interaction studies conducted in normal volunteer subjects showed that terbinafine does not affect the clearance of antipyrine or digoxin. Terbinafine decreases the clearance of caffeine by 19%. Terbinafine increases the clearance of cyclosporine by 15%.

There have been spontaneous reports of increase or decrease in prothrombin times in patients concomitantly taking oral terbinafine and warfarin, however, a causal relationship between LAMISIL^® Tablets and these changes has not been established.

Terbinafine clearance is increased 100% by rifampin, a CyP450 enzyme inducer, and decreased 33% by cimetidine, a CyP450 enzyme inhibitor. Terbinafine clearance is unaffected by cyclosporine.

There is no information available from adequate drug-drug interaction studies with the following classes of drugs: oral contraceptives, hormone replacement therapies, hypoglycemics, theophyllines, phenytoins, thiazide diuretics, beta blockers, and calcium channel blockers.