Kenalog_in_Orabase: profile and news

WHAT TO DO FOR CANKER SORES Jul 28, 2005
Lidocaine viscous is another treatment that curbs the sting of canker sores. Kenalog in Orabase minimizes canker-sore irritation and promotes healing. ... - Charlotte Sun-Herald

Other information

Indication
For the treatment of perennial and seasonal allergic rhinitis

Pharmacology
Triamcinolone and its derivatives are synthetic glucocorticoids that are used for their antiinflammatory or immunosuppressive properties.

Mechanism Of Action
The antiinflammatory actions of corticosteroids are thought to involve lipocortins, phospholipase A2 inhibitory proteins which, through inhibition of arachidonic acid, control the biosynthesis of prostaglandins and leukotrienes. The immune system is suppressed by corticosteroids due to a decrease in the function of the lymphatic system, a reduction in immunoglobulin and complement concentrations, the precipitation of lymphocytopenia, and interference with antigen-antibody binding.

Drug Category
Glucocorticoids; Anti-inflammatory Agents; Adrenergic Agents; ATC:A01AC01; ATC:D07AB09; ATC:D07XB02; ATC:H02AB08; ATC:R01AD11; ATC:R03BA06; ATC:S01BA05

Brand Names/Synonyms
Adcortyl; Aristocort; Aristocort A; Aristocort Tablets; Aristogel; Aristospan; Azmacort; CL 19823; Celeste; Cinolone; Cinolone-T; Delphicort; Fluoxiprednisolone; Fluoxyprednisolone; Flutex; HSDB 3194; Kenacort; Kenacort-A; Kenacort-Ag; Kenalog; Kenalog in Orabase; Kenalog-10; Kenalog-40; Kenalog-H; Ledercort; Nasacort; Nasacort Aq; Nasacort Hfa; Omcilon; Omicilon; Oracort; Oralone; Orion; Polcortolon; Rodinolone; Sk-Triamcinolone; Tiamcinolonum [Inn-Latin]; Tri-Nasal; Triacet; Triacort; Triam-Tablinen; Triamcet; Triamcinalone; Triamcinlon; Triamcinolon; Triamcinolona [Inn-Spanish]; Triamcinolone; Triamcinolone Acetonide; Triamcinolone Acetonide in Absorbase; Triamcinolone Diacetate; Triamcinolone [Usan:Ban:Inn:Jan]; Triamcinolonum [Inn]; Triatex; Tricortale; Triderm; Trymex; Vetalog; Volon

Dosage Forms
CREAM; LIQUID; METERED-DOSE (AEROSOL); OINTMENT; PASTE; SUSPENSION; SYRUP; TABLET

Absorption
Rapid absorption following oral administration

Interactions
Not Available

Chemical IUPAC Name
9-fluoro-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

Chemical Formula
C21H27FO6

Half Life
88 minutes

Drug Type
Approved Drug

# Accession No
APRD00422

CAS Registry Number
124-94-7