Kadian: profile and news

GSK diabetes drug Avandia reported to cause eye problems  Feb 16, 2006
The FDA alerted Medwatch about numerous reports that Avandia, a diabetes drug manufactured by GlaxoSmithKline, has been causing a swelling at the back of the ... - Newstarget.com,

Major Canadian Type 2 Diabetes Study Shows Significant Improvement ...  Feb 21, 2006
TORONTO, CANADA -- February 21, 2006 -- Data from a major new Canadian primary-care study show that the combination of rosiglitazone maleate (Avandia®) and low ... - DG News

Blockbuster sales boost Glaxo profits  Feb 8, 2006
16 per cent increase in full year profits to £6.73 billion before tax today - boosted by strong sales of its asthma drug Advair and diabetes medicine Avandia. ... - Times Online,

GlaxoSmithKline 4Q Profit Up 45 Percent  Feb 8, 2006
..."Looking into 2006, the strong growth seen from key products such as Seretide/Advair, Avandia and from our vaccines business is set to continue, and we expect ... - Houston Chronicle,

Glaxo beats hopes with profits rise  Feb 8, 2006
Pharmaceuticals giant GlaxoSmithKline today said soaring sales of its asthma drug Advair and diabetes medication Avandia drove profits up 16%. ... - Ireland Online,

Sales send Glaxo profits soaring  Feb 8, 2006
SOARING sales of its asthma drug Advair and diabetes medication Avandia drove GlaxoSmithKline profits up 16 per cent. The pharmaceuticals ... - Manchester Evening News,

Glaxo profits growth beats hopes  Feb 8, 2006
Pharmaceuticals giant GlaxoSmithKline has said soaring sales of its asthma drug Advair and diabetes medication Avandia drove profits up 16%. ... - Virgin.net,

2005 - the year of recovery for GSK  Feb 9, 2006
...company's top-selling product, Seretide/Advair (salmeterol and fluticasone) for asthma, leapt 22% to £3 billion; combined sales of Avandia (rosiglitazone) and ... - Pharma Times (subscription),

Glaxo profit up 17% on good sales  Feb 8, 2006
...before. Sales of Advair were up 22% in 2005 to more than £3bn, while diabetes medication Avandia increased by 18% to £1.3bn. Glaxo ... - BBC News,

Glaxo Predicted To Report 7% Sales Gain for 2005  Feb 7, 2006
...full-year 2005. He cited the drugs Seretide, Avandia, Lamictal, Valtrex, Coreg and vaccines, as key drivers for sales. He added ... - Forbes

Asthma drug boosts Glaxo  Feb 9, 2006
DRUGS giant GlaxoSmithKline has reported a 16 per cent hike in profits boosted by healthy sales of asthma treatment Advair and diabetes medication Avandia. ... - Scotsman,

Glaxo assures focus on pipeline  Feb 8, 2006
Garnier added, "Looking into 2006, the strong growth seen from key products such as Seretide/Advair, Avandia and from our vaccines business is set to continue ... - Life Style Extra,

Europe's largest drugmaker GlaxoSmithKline reports 17% rise in ...  Feb 8, 2006
Sales of Advair were up 22% in 2005 to more than £3bn, while diabetes medication Avandia increased by 18% to £1.3bn. Vaccines rose 15% to £1.4bn. ... - FinFacts Ireland,

GlaxoSmithKline 4Q profits up 45%  Feb 8, 2006
The company said sales of its diabetes drug, Avandia, jumped 26% to £289 million. GlaxoSmithKline witnessed a 17% rise in vaccine sales to £420 million. ... - New Ratings

Sales and profits surge at Glaxo  Feb 8, 2006
Sales of bestselling Advair surged 22% to more than £3bn, while Avandia for diabetes was up 18% to £1.3bn and vaccines were up 15% to £1.4bn. ... - The Herald,

Generic Products Compete With GlaxoSmithKline  Feb 9, 2006
...drug. The sales figure for Avandia was at £289 million for the same quarter, while Avandamet crossed the £46 million figure. The ... - MedIndia,

Glaxo in sales surge  Feb 9, 2006
PHARMACEUTICALS giant Glaxo-SmithKline yesterday said soaring sales of its asthma drug Advair and diabetes medication Avandia drove profits up 16%. ... - ic CheshireOnline,

Avandaryl: New Combined Drug for Type 2 Diabetes  Feb 8, 2006
Recently approved by the US Food and Drug Administration, Avandaryl is the first and only tablet to combine a thiazolidinedione - know as Avandia - with a ... - About - News & Issues,

FDA Approves GSK Diabetes Combination Therapy  Feb 4, 2006
Avandaryl combines Avandia and Amaryl, two other diabetes drugs for the control of blood sugar levels. As an adjunct to diet and ... - International News Service,

GlaxoSmithKline launches Avandaryl  Feb 1, 2006
The treatment, which combines the company's diabetes treatments Avandia and Amaryl, received Food and Drug Administration approval in December. ... - BusinessWeek

New Type 2 Diabetes Drug Hits Market  Feb 1, 2006
...market. The drug, called Avandaryl, combines two other diabetes drugs -- Avandia and Amaryl -- to help improve control of blood sugar. ... - FOX News

GlaxoSmithKline Announces the Approval and Availability of ...  Feb 1, 2006
FDA), Avandaryl is the first and only tablet to combine a thiazolidinedione (TZD), rosiglitazone maleate - separately marketed as Avandia(R) - with a ... - PharmaLive.com (press release),

Glaxo wins approvals for drugs  Feb 1, 2006
Avandaryl, which combines Glaxo's popular Avandia medicine and a member of an older class of treatment called sulphonylureas, had originally been slated for ... - Scotsman,

Glaxo launches diabetes drug Avandaryl in US  Jan 31, 2006
...regulators. Avandaryl combines Glaxo's popular Avandia medicine and a member of an older class of treatment called sulphonylureas. ... - Reuters

Glaxo's Type 2 diabetes combo drug OK'd  Feb 1, 2006
The new treatment combines into one tablet two already-marketed Glaxo products, Avandia -- thiazolidinedione (TZD), rosiglitazone maleate -- and Amaryl ... - United Press International

GSK debuts Avandaryl for diabetes in the USA  Feb 2, 2006
Avandaryl is based on GSK's Avandia (rosiglitazone maleate) and the active ingredient in Sanofi-Aventis' Amaryl (glimepiride), now generically available in the ... - Pharma Times (subscription),

Cherry Picking in Drug Discovery  Feb 23, 2006
Project leaders for blockbuster drugs such as Glivec, Viagra and Avandia will explain the process that lies behind the development of these products, including ... - GenomicsProteomics.com (press release),

FDA approves GSK diabetes combination therapy  Feb 2, 2006
By Staff Writer. Avandaryl combines Avandia and Amaryl, two other diabetes drugs for the control of blood sugar levels. As an adjunct ... - Pharmaceutical Business Review

GSK FY at top of forecasts; sees 'around 10 pct' 2006 EPS growth ...  Feb 8, 2006
...bln stg. Sales of diabetes drug Avandia/Avandamet rose 18 pct to 1.3 bln stg, while vaccines sales were up 15 pct to 1.4 bln. 'We ... - Forbes

GlaxoSmithKline earnings rise 45%  Feb 8, 2006
...rose 23% to 851 million pounds. Sales of diabetes drug Avandia climbed 26% to 289 million pounds. The company earlier in the year ... - MarketWatch

GSK annual results top forecast; beats hopes on 2006 guidance ...  Feb 8, 2006
Sales of diabetes drug Avandia/Avandamet rose 18 pct to 1.3 bln stg, while total pharmaceutical sales climbed 8 pct in constant currency terms, to 18.7 bln stg ... - Forbes

GSK hints at joining $10bn auction  Feb 8, 2006
Helped by higher sales of core drugs such as Advair for asthma and the diabetes treatment Avandia, group sales rose 8% to £21.66bn. ... - Guardian Unlimited,

Glaxo 4Q earnings set up acquisitive speculation  Feb 10, 2006
Avandia continues to maintain its momentum in the TZD class of anti-diabetic agents with sales for the quarter reaching £289 million – an increase of 26 per ... - In-PharmaTechnologist.com,

World Briefing Europe, Asia  Feb 8, 2006
...product, the asthma drug Seretide/Advair, rose 22 percent to just over £3 billion ($5.2 billion), while sales of its diabetes treatment Avandia/Avandamet rose ... - New York Times,

Today's Business  Feb 9, 2006
...just more than $5.2 billion. Sales of its diabetes treatment Avandia/Avandamet rose 18 percent, to $2.3 billion, over the year. - Myrtle Beach Sun News,

Buyback in view as BP heads for GBP12bn profit  Feb 6, 2006
...billion. Much of the growth in profits comes from sales of the blockbuster asthma drug Seretide and diabetes treatment Avandia. ... - TMCnet

Healthcare: MSD Readies Ground for Diabetes Launch  Feb 17, 2006
Last week GlaxoSmithKlein launched Avandaryl in the US. It is the first tablet treatment to combine commonly prescribed Avandia and Amaryl. ... - International News Service,

GSK's lung cancer drug Hycamtin gets European OK  Feb 1, 2006
The product is a combination of GSK's Avandia and Sanofi-Aventis SA's Amaryl. At 11.00 am GSK shares were trading 11 pence higher at 1449. - Forbes

Use with Other Central Nervous System Depressants: The depressant effects of morphine are potentiated by the presence of other CNS depressants such as alcohol, sedatives, antihistaminics, or psychotropic drugs. Use of neuroleptics in conjunction with oral morphine may increase the risk of respiratory depression, hypotension and profound sedation or coma.

Interaction with Mixed Agonist/Antagonist Opioid Analgesics: Agonist/antagonist analgesics (i.e., pentazocine, nalbuphine, butorphanol, or buprenorphine) should NOT be administered to patients who have received or are receiving a course of therapy with a proof opioid agonist analgesic. In these patients, the mixed agonist/antagonist may alter the analgesic effect or may precipitate withdrawal symptoms.