Ionamin: profile and news

SPORTCHECK: No dope cheats but awareness is lacking Mar 4, 2006
Drugs such as Duromine/Ionamin which are used as an appetite suppressant (anti-obesity) are banned substances by WADA and can have serious effects on health ... - Malay Mail,

OPENING ARGUMENTS START MONDAY IN 'FEN-PHEN TRIAL' Jan 29, 2006
...distribute, supply, market, sell, advertise and otherwise distribute in interstate commerce the diet drugs Pondimin (fenfluramine) and Ionamin (phentermine).". ... - Tyler Morning Telegraph,

Shedding Pounds: Drugs not likely to be solution to obesity Aug 15, 2005
Phentride and Ionamin (phentermine), Tenuate (diethylpropion), Didrex (benzphetamine), and Obezine, Bontril and Adipost (phendimetrazine) are relatives of ... - Winston-Salem Journal,

Weight loss pills available fail to take a big bite out of obesity Aug 1, 2005
Phentride and Ionamin (phentermine), Tenuate (diethylpropion), Didrex (benzphetamine), and Obezine, Bontril and Adipost (phendimetrazine) are all relatives of ... - Naples Daily News (subscription)

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...to ban online pharmacies from shipping to their state because the patient has not physically met with a doctor before ordering Phentermine, Adipex, or Ionamin. ... - Khalsa News Network

Phentermine Online Pharmacy Has the Solution Apr 5, 2005
Once approved, a prescription for Phentermine, Xenical, Adipex, Meridia, Didrex, Ionamin, Tenuate, Bontril or Phendimetrazine will be discreetly and safely ... - Khalsa News Network

Prescription Diet Pills Plus New Year’s Resolutions Equal Weight ... Apr 5, 2005
...weight. Various prescription diet pills are available online including Phentermine, Ionamin, Meridia, Adipex, and Xenical. (These ... - Khalsa News Network

US-Meds.com Offers Phentermine at Discount Prices and Their ... Apr 4, 2005
...pressure even though their patients would benefit tremendously from taking Phentermine or one of its name brand counterparts like Adipex, Ionamin or Fastin. ... - Khalsa News Network

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...are big sellers for online pharmacies because many doctors will no longer prescribe weight loss pills such as Phentermine, Adipex, Ionamin, Didrex, Bontril and ... - Khalsa News Network

Save Money on Prescriptions Apr 5, 2005
Various prescription diet pills are available online including Phentermine, Ionamin, Meridia, Adipex, Phendimetrazine, Tenuate, Bontril, Didrex and Xenical. ... - Khalsa News Network

Adipex Online, Buy Phentermine, Meridia...Online Searches like ... Apr 5, 2005
...diet pill searches online. At a lesser amount, web surfers look for other ones like Meridia or Ionamin. Some comments at online ... - Khalsa News Network

Buy Phenterprin HCL, New Weight Loss Product to Lose Weight Apr 5, 2005
Phenterprin HCL is an alternative to prescription weight loss products such as phentermine, adipex, ionamin, bontril, meridia, and didrex. ... - Khalsa News Network,

Buy Phenterprin HCL, New Weight Loss Product to Lose Weight, at ... Feb 28, 2005
Phenterprin HCL is an alternative to prescription weight loss products such as phentermine, adipex, ionamin, bontril, meridia, and didrex. ... - PR Web (press release),

Other information

Indication
Indicated for the treatment and management of obesity.

Pharmacology
Phentermine is indicated in the management of exogenous obesity as a short term (a few weeks) adjunct in a regimen of weight reduction based on caloric restriction. Phentermine hydrochloride is a sympathomimetic amine with pharmacologic activity similar to the prototype drugs of this class used in obesity, the amphetamines. Actions include central nervous system stimulation and elevation of blood pressure. Tachyphylaxis and tolerance have been demonstrated with all drugs of this class in which these phenomena have been looked for.

Mechanism Of Action
Phentermine is an amphetamine that stimulates neurons to release or maintain high levels of a particular group of neurotransmitters known as catecholamines; these include dopamine and norepinephrine. High levels of these catecholamines tend to suppress hunger signals and appetite. Phentermine (through catecholamine elevation) may also indirectly affect leptin levels in the brain. It is theorized that phentermine can raise levels of leptin which signal satiety. It is also theorized that increased levels of the catecholamines are partially responsible for halting another chemical messenger known as neuropeptide Y. This peptide initiates eating, decreases energy expenditure, and increases fat storage.

Drug Category
Adrenergic Agents; Appetite Depressants; Central Nervous System Agents; Anorexigenic Agents; Stimulants; ATC:A08AA01; ATC:C01CA11

Brand Names/Synonyms
Adipex-P; Alpha,Alpha-Dimethylphenethylamine; Duromine; Fastin; Inoamin; Ionamin; Linyl; Lipopill; Lonamin; Mirapront; Normephentermine; Obenix; Obestin-30; Oby-Trim; Omnibex; Ona Mast; Ona-Mast; Phentercot; Phentermine; Phentermine Hcl; Phentermine Hydrochloride; Phentermine Resin 30; Phentride; Pre-Sate; Pro-Fast; Rcra Waste Number P046; Teramine; Tora; Uritone; Wilpo; Wyamine Sulfate; Zantryl

Dosage Forms
CAPSULE

Absorption
Phentermine is rapidly absorbed after oral ingestion.

Interactions
Interactions for Phentermine:

Concomitant use of alcohol with phentermine hydrochloride may result in an adverse drug interaction.

Chemical IUPAC Name
2-methyl-1-phenyl-propan-2-amine

Chemical Formula
C10H15N

Half Life
16 to 31 hours

Drug Type
Approved Drug

# Accession No
APRD00093

CAS Registry Number
122-09-8