Halfan: profile and news
T@P Socially and scientifically, conservatives are turning their ... Nov 20, 2005
...up from the audience, Agyarko explained how one month earlier he had discovered a deadly counterfeit of the children’s malaria syrup Halfan, which had been ... - The American Prospect,
Mums tell website not-so-Rosie stories Nov 18, 2005
But mum Gemma Nightingale described how halfan- hour later a doctor revealed Lewis had taken a breath by himself and was on a ventilator. ... - Cambridge Evening News,
Constable beaten up by four Nov 25, 2005
...discharged on Friday evening. Dilip said the four were in inebriated condition and assaulted him for almost halfan-hour. The police have ... - Times of India,
HK Disneyland theme park expansion planned: tourism official Sep 17, 2005
The first weekend (Saturday and Sunday) after the formal opening of Hong Kong Disneyland witnesses the theme park open halfan hour earlier than the schedule to ... - Xinhua,
More report at Under-20 camp Jul 25, 2005
Those not in the camp without permission are Abdulrahman Paul, Jumanne Ramadhani, Julius Mrope, Nizar Halfan, Jacob Masawe, Meshack David Nyambele, Aziz Raja ... - IPPMEDIA - Guardian
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SRI International Celebrates 50 Years of Drug Discovery and ... Jun 20, 2005
The Food and Drug Administration (FDA) approved halofantrine as an antimalarial in 1992 under the SmithKline Beecham (now GlaxoSmithKline) brand name, Halfan(R ... - Business Wire (press release),
SRI International Celebrates 50 Years of Drug Discovery and ... Jun 20, 2005
The Food and Drug Administration (FDA) approved halofantrine as an antimalarial in 1992 under the SmithKline Beecham (now GlaxoSmithKline) brand name, Halfan(R ... - Business Wire (press release),
The Global Threat of Counterfeit Drugs: Why Industry and ... Mar 11, 2005
One of us (K. Agyarko) found counterfeits of the GSK paediatric anti-malarial syrup halofantrine (Halfan) in August 2002 in Ghana. ... - PharmaLive.com (press release),
One in seven drugs fake worldwide, claims report Mar 13, 2005
For example, in December of 2000, Belgian customs seized 57,600 packs of fake Halfan (halofantrine) capsules, an antimalarial sold by GlaxoSmithKline - en ... - in-PharmaTechnologist,
One in seven drugs fake worldwide, claims report 14 Mar 2005
For example, in December of 2000, Belgian customs seized 57,600 packs of fake Halfan (halofantrine) capsules, an antimalarial sold by GlaxoSmithKline - en ... - in-PharmaTechnologist,
The Global Threat of Counterfeit Drugs: Why Industry and ... Mar 11, 2005
One of us (K. Agyarko) found counterfeits of the GSK paediatric anti-malarial syrup halofantrine (Halfan) in August 2002 in Ghana. ... - PharmaLive.com (press release),
Other information
Indication
For treatment of Severe malaria
Pharmacology
Halofantrine is a synthetic antimalarial which acts as a blood schizonticide. It is effective against multi drug resistant (including mefloquine resistant) P. falciparum malaria.
Mechanism Of Action
The mechanism of action of Halofantrine may be similar to that of chloroquine, quinine, and mefloquine; by forming toxic complexes with ferritoporphyrin IX that damage the membrane of the parasite.
Drug Category
Antimalarials; ATC:P01BX01
Brand Names/Synonyms
Halfan; Halofantrina; Halofantrina [Inn-Spanish]; Halofantrine; Halofantrine [Usan]; Halofantrinum; Halofantrinum [Inn-Latin]
Dosage Forms
TABLET
Absorption
Not Available
Interactions
Not Available
Chemical IUPAC Name
3-dibutylamino-1-[1,3-dichloro-6-(trifluoromethyl)phenanthren-9-yl]-propan-1-ol
Chemical Formula
C26H30Cl2F3NO
Half Life
6-10 days
Drug Type
Approved Drug
# Accession No
APRD00419
CAS Registry Number
69756-53-2