Haldol: profile and news

Harper’s Findings  Mar 5, 2006
Gastroenterologists announced that milk-thistle extract does not help patients with liver disease, though green-tea extract does appear to help people with ... - Arkansas Democrat-Gazette (subscription),

AVOIDING THE WRATH OF GRAPES  Mar 5, 2006
According to the manufacturer’s Web site and an e-mail from the company, Sober X uses ingredients like milk thistle and artichoke to help the body metabolize ... - Monitor,

Canned Heat  Mar 1, 2006
...drink. Most energy drinks boast ingredients such as taurine, guarana, D-Ribose, maldodextrine, ginseng and even milk thistle. These ... - Syracuse Post Standard,

Shane Watson  Mar 2, 2006
There's the milk thistle supplement (always remembered too late). The Pepto-Bismol option. Some like Ribena and a banana, others Marmite on any surface. ... - New Statesman,

Herbal Supplements Could Cause Dangerous Side Effects During ...  Feb 19, 2006
Other common supplements taken by patients in the study that may cause dangerous side effects included gingko biloba, goldenseal, milk thistle, ginseng, kava ... - Medical News Today (press release),

Beauty therapy  Feb 14, 2006
Keep your system clean Try Hambleden Herbs liver detoxifying Organic Milk Thistle (£11.95, 01273-242925) and Divia Body Cleanse Tea (£10, balancing-energy.com ... - Telegraph.co.uk,

Activate Beauty Taps Cruz/Kravetz: Ideas as Marketing Agency of ...  Feb 13, 2006
...exotic elements like Cupuaçu Butter, Sea Buckthorn, and Macadamia Nut Oil; and nourishing components like Vanilla Bean, Vitamin B-5, Milk Thistle, and Aloe ... - Hispanic PR Wire (press release),

Milk thistle is excellent for liver  Jan 18, 2006
Would milk thistle be safe for him to take to help his liver? A: Milk thistle is an excellent herb to help promote normal liver health. ... - Fort Wayne News Sentinel,

Give up smoking with some natural help  Jan 10, 2006
Cigarette smoke releases poisonous heavy metals, including cadmium, into the system and the herb Milk Thistle and these green foods can offer heavy metal ... - Open PR (press release),

The A to Z recipe for a healthy life  Jan 7, 2006
Silybin, a component of milk thistle, protects the liver from environmental toxins and also stimulates super-oxide dismutase (SOD) activity. ... - The Observer,

Inflammation in joints cause of discomfort  Jan 23, 2006
A: Although surgery may be the only option, you could try a preparation called Milk Thistle Complex, which is a herbal tincture combining a number of liver ... - Belfast Telegraph,

New year detox 'is waste of money'  Jan 9, 2006
...worthless - absolute rubbish. The ones I would always recommend are milk thistle, artichoke, and dandelion leaf and root. "The root ... - Scotsman,

OFF THE RECORD  Jan 9, 2006
What was the choice of tipple? Milk Thistle extract? Peppermint tea? Er... more like the restorative benefits of whisky, vodka and beer. ... - Glasgow Daily Record,

Many turn to alternatives to take care of the aches  Jan 14, 2006
A non-traditional medicine Web Site, http://www.worldwidehealthcenter.com, lists a variety of non-traditional remedies such as milk thistle, artichoke formula ... - Baraboo News Republic,

Can diet curb my terrible headaches?  Jan 16, 2006
If, despite these precautions, you still wake up with a hangover headache, try 350mg of milk thistle, three times a day, as this traditional detox remedy can ... - Times Online,

Open and closed doors at the ‘Hut’  Jan 22, 2006
...grown agriculture products and retail outlets that feature locally grown food features everything from chickens and eggs to gladiolas and milk thistle. ... - Helena Independent Record,

Beautiful skin  Jan 14, 2006
Liver tonics such as milk thistle and dandelion may be beneficial as they improve liver function, regenerate new liver cells, improve bile flow and promote ... - Malaysia Star,

Detox dilemmas  Jan 6, 2006
...the fastest methods I know of for getting nutrients into the blood system," though she also recommends products such as nettle tea, milk thistle and dandelion ... - Financial Times,

Keep a clear head this festive season  12 Dec 2005
It contains extracts of milk thistle (silybum marianum), as well as lecithin that contains choline to enhance the liver’s functioning, and inositol, an ... - Independent Online,

Nutrients for the skin  Dec 10, 2005
...medicines. Herbalists hold milk thistle and dandelion in high regard. ... gallstones. Silymarin is a potent antioxidant found in milk thistle. ... - Malaysia Star,

Herbal Remedies for this Festive Season  Dec 6, 2005
Milk Thistle – to aid the liver to recover from over-zealous celebrations. Research indicates that Milk thistle offers protection to the liver from damage. ... - I-Newswire.com (press release)

Get ready for a healthy Christmas  Dec 7, 2005
If you are really going all out on the alcohol, then extra help in the form of the herbal formula Milk Thistle is also advisable. ... - ic Scotland.co.uk,

RICH food and booze are hard to avoid at this time of year.  Nov 28, 2005
Try Cantassium Micro Vitamins folic acid 400g onea-day (£4.25). Cynara's Milk Thistle (£7.99 for 30 tablets) is renowned for its liver- boosting properties. ... - Glasgow Daily Record,

Energy Drinks ... Power to the People?  Nov 12, 2005
...of the ingredients in the Rockstar Energy Drink sent them scurrying to their reference books to read up on exotic ingredients such as milk thistle and guarana. ... - Bremerton Sun (subscription),

Eat, drink and be wary of morning after night before  Nov 28, 2005
...says: "It has a lot of bitter herbs that stimulate the digestion, some ginger for nausea and there are also tonic herbs in it like milk thistle which have ... - Scotsman,

Do-it-yourself detox diary  Nov 17, 2005
...with gin and lime juice on a hot day, unfortunately), a bottle of powdered herbs dubbed "colon care" (a laxative in disguise), a bottle of milk thistle to help ... - Stuff.co.nz,

Researcher Puts Gas Under Pressure for Supercritical Fluid ...  Nov 10, 2005
Clausen and Carrier developed a water-based extraction process for milk thistle, a plant containing compounds that may have therapeutic value in treating ... - PhysOrg.com,

Gourmet weight loss  Nov 14, 2005
In addition, I’d take a couple of remedies to help you along: 300mg of milk thistle twice a day (a traditional herbal remedy that will help you to detox ... - Times Online,

Get back in the black  Nov 13, 2005
Here are a couple of remedies to help you along: 300mg twice a day of milk thistle (a traditional remedy that dieters find helps them to detox), and 20ml of ... - Times Online,

Merced man wants medical pot returned  Nov 24, 2005
Wilson has been drinking a lot of Ensure nutrition shakes to try to get his weight up. He also takes herbs like milk thistle to help his liver. ... - Modesto Bee,

Readers give advice for Dizzy's vertigo  Nov 12, 2005
...away. If I have a flare-up, I use milk thistle tablets. Wyoming: Tell her to get tested for celiac sprue (gluten intolerance). She ... - Biloxi Sun Herald,

Cholesterol Part 1  Nov 16, 2005
Nature’s Sunshine’s Enviro-Detox, All Cell Detox, and Milk Thistle Combination support the body’s detoxification processes. ... - Topsail Island Info News,

More pet owners try alternative medicine  Nov 11, 2005
Some herbs used include milk thistle, which provides liver support; Echinacea, which aids the immune system; and licorice or ginger, which help the intestinal ... - DetNews.com,

WayPoint Biomedical and Sober X USA Sign Letter of Intent for ...  Nov 10, 2005
Sober X provides a unique formula of Milk Thistle, Artichoke, Green Tea and Vitamin C, specifically designed to supply the body with a constant supply of high ... - Market Wire (press release)

DR GARETH: COMPLEMENTARY MEDICINE: HELP ME SHED THE UNWANTED ...  Oct 29, 2005
Take 20 drops of Milk Thistle Complex in a little water three times a day about 15 minutes before each meal to improve liver and biliary tract functioning. ... - Glasgow Sunday Mail,

Study may help prevent liver disease  Oct 11, 2005
Science: Milk thistle is over-rated (May 3, 2005) -- Danish scientists say milk thistle, an alternative medicine, was not shown to extend the lives of people ... - Science Daily (press release)

Balance | Special Feature: Detox diets might be fashionable, but ...  Oct 18, 2005
Some detox plans promote consuming extracts, such as milk thistle, and others encourage unconventional recipes, like alfalfa, algae and barley grass smoothies. ... - Tufts Daily,

FANCL Announces Research Results of Antiaging Material Silybin at ...  Oct 5, 2005
...cosmetic manufacturer FANCL announced on September 29 that it has presented research results of silybin, an extract derived from milk thistle seeds, at the ... - Japan Corporate News (press release),

FANCL to Bring to Market New Antiaging Supplement in December  Oct 6, 2005
The new product, which contains silybin (an extract of milk thistle), HTC collagen, and soybean saponin, is an optimal choice for those who concerning anti ... - Japan Corporate News (press release),

Alt.Health  Sep 28, 2005
Drink the juice of half a lemon squeezed into 8 ounces of water to help detoxify the liver. Supplement with milk thistle . Eliminate ... - Now Toronto,

Botanical-based remedies best way to treat illness, advocates say  Oct 1, 2005
Saw Palmetto, for example, has been proven effective for male prostate gland disorders. Milk thistle is acknowledged as being beneficial to liver functions. ... - KVOA.com,

Source: Nature's Gate  Oct 5, 2005
This revolutionary formula is enriched with Phyto-actives found in Milk Thistle, Soy, Sea Algae and Wheat Proteins to help reduce the tell-tale signs of ... - Yahoo! News (press release)

Study may help prevent liver disease  11 Oct 2005
Science: Milk thistle is over-rated (May 3, 2005) -- Danish scientists say milk thistle, an alternative medicine, was not shown to extend the lives of people ... - Science Daily (press release)

Try low-fat diet to break down gall stones  Sep 26, 2005
My test for liver lipids is very high. I'm on milk thistle complex. Can you suggest an appropriate diet and medication I should be taking. ... - Belfast Telegraph,

FANCL Announces Research Results of Antiaging Material Silybin at ...  Oct 5, 2005
...cosmetic manufacturer FANCL announced on September 29 that it has presented research results of silybin, an extract derived from milk thistle seeds, at the ... - Japan Corporate News (press release),

FANCL to Bring to Market New Antiaging Supplement in December  Oct 6, 2005
The new product, which contains silybin (an extract of milk thistle), HTC collagen, and soybean saponin, is an optimal choice for those who concerning anti ... - Japan Corporate News (press release),

Alt.Health  Sep 28, 2005
Drink the juice of half a lemon squeezed into 8 ounces of water to help detoxify the liver. Supplement with milk thistle . Eliminate ... - Now Toronto,

Source: Nature's Gate  Oct 5, 2005
This revolutionary formula is enriched with Phyto-actives found in Milk Thistle, Soy, Sea Algae and Wheat Proteins to help reduce the tell-tale signs of ... - Yahoo! News (press release)

Herbs that de-liver  Sep 24, 2005
Milk thistle is one of the most researched and best understood of all medicinal herbs. It has been found that milk thistle’s active ... - Malaysia Star,

Botanical-based remedies best way to treat illness, advocates say  Oct 1, 2005
Saw Palmetto, for example, has been proven effective for male prostate gland disorders. Milk thistle is acknowledged as being beneficial to liver functions. ... - KVOA.com,

Personalized Medicine: Start Saving for It  Sep 28, 2005
...who drinks alcohol but doesn't smoke, exercises and sleeps well but has arthritis, should take certain supplements -- everything from calcium to milk thistle. ... - Always On

Lightning in a Can  Sep 16, 2005
Rockstar is loaded with B vitamins as well as compounds purported to increase energy and mental acuity, such as taurine, milk thistle and ginkgo biloba. ... - Los Angeles Times,

Greensboro's ten best energy drinks  Sep 13, 2005
...power. It contains all the normal energy drink ingredients — guarana, caffeine, carnitine, and ginseng — plus milk thistle. ... - Yes! Weekly,

New raw material supplier cuts out middlemen  Sep 20, 2005
...supplies other commodities, including pyridoxal 5 phosphate, methylcobalamin, vitamin K USP, glucosamine, Saint John's wort, gingko and milk thistle extracts. ... - NutraIngredients-usa.com,

Natural Pets  Sep 21, 2005
...bedtime. To support his liver, which may have been damaged from years of medication, he receives a dandelion-milk thistle supplement. ... - Clarke Times Courier,

An encephalopathic syndrome (characterized by weakness, lethargy, fever, tremulousness and confusion, extrapyramidal symptoms, leukocytosis, elevated serum enzymes, BUN, and FBS) followed by irreversible brain damage has occurred in a few patients treated with lithium plus HALDOL. A causal relationship between these events and the concomitant administration of lithium and HALDOL has not been established; however, patients receiving such combined therapy should be monitored closely for early evidence of neurological toxicity and treatment discontinued promptly if such signs appear.

As with other antipsychotic agents, it should be noted that HALDOL may be capable of potentiating CNS depressants such as anesthetics, opiates, and alcohol.

In a study of 12 schizophrenic patients coadministered oral haloperidol and rifampin, plasma haloperidol levels were decreased by a mean of 70% and mean scores on the Brief Psychiatric Rating Scale were increased from baseline. In 5 other schizophrenic patients treated with oral haloperidol and rifampin, discontinuation of rifampin produced a mean 3.3-fold increase in haloperidol concentrations. Thus, careful monitoring of clinical status is warranted when rifampin is administered or discontinued in haloperidol-treated patients.

Chemical IUPAC Name
4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]-1-(4-fluorophenyl)-butan-1-one

Chemical Formula
C21H23ClFNO2

Half Life
3 weeks

Drug Type
Approved Drug

# Accession No
APRD00538

CAS Registry Number
52-86-8