Furosemide: profile and news

Aurobindo Pharma receives final US FDA approval for Mirtazapine ...  Mar 2, 2006
Aurobindo Pharma Ltd has announced that US FDA has granted final approval for its 45mg Mirtazapine orally disintegrating tablet (ODT). ... - domain-B,

Aurobindo’s receives final approval of Mirtazapine ODT 45 mg for ...  Mar 2, 2006
Aurobindo Pharma is pleased to announce that the US FDA has granted final approval for Aurobindo’s Mirtazapine Orally Disintegrating Tablet (ODT) 45 mg. ... - Moneycontrol.com,

Aurobindo wins nod for anti-depressant  Mar 2, 2006
Aurobindo Pharma Ltd. announced on Thursday that the US FDA has granted it a final approval for its Mirtazapine Orally Disintegrating Tablet (ODT) 45 mg. ... - India Infoline.com,

Battling the blues  Feb 20, 2006
The study, published in this month's Journal of Clinical Psychopharmacology, found that mirtazapine, first distributed in Canada in 2004, can act up to four ... - Ottawa Sun,

Trimipramine for Refractory Panic Attacks  Mar 2, 2006
Fluoxetine and olanzapine were discontinued, and mirtazapine, 15 mg at night, was begun with the longstanding alprazolam, 2 mg/day. ... - Am J Psychiatry (subscription)

STAR*D Preliminary Findings Provide Clearer Picture of Major ...  Feb 27, 2006
Those patients without remission after two adequate trials with antidepressants could proceed to Level 3. Options at Level 3 were mirtazapine (Remeron) or ... - Psychiatric Times,

Aurobindo Pharma’s drug gets USFDA nod  Mar 2, 2006
...said on Thursday it had received final approval from the US Food and Drug Administration to sell its antidepressant drug mirtazapine. ... - Sify,

Antidepressants and your libido  Feb 28, 2006
Antidepressants found to have fewer sexual effects include Wellbutrin, Serzone (nefazodone), Remeron (mirtazapine) or Zyban (bupropion). ... - Health24.com,

Two-week delay in onset of action of antidepressants: new evidence  Feb 14, 2006
Szegedi, A., Muller, MJ, Anghelescu, I., et al (2003) Early improvement under mirtazapine and paroxetine predicts later stable response and remission with high ... - British Journal of Psychiatry (subscription),

Akzo Nobel planning IPO for pharma business  Feb 7, 2006
...posted a 3% rise in revenues to 2.45 billion euros, returning to growth after several years of decline since antidepressant Remeron (mirtazapine) lost patent ... - Pharma Times (subscription),

Akzo Nobel planning IPO for pharma business  Feb 7, 2006
...posted a 3% rise in revenues to 2.45 billion euros, returning to growth after several years of decline since antidepressant Remeron (mirtazapine) lost patent ... - Pharma Times (subscription),

Brief Reports: Patterns of Psychotropic Medication Use by Race ...  Jan 25, 2006
...amoxapine. Other antidepressants included bupropion, venlafaxine, maprotiline, trazodone, mirtazapine, and nefazodone. Benzodiazepines ... - Psychiatric Services (subscription)

New treatment for sleep illness  Jan 13, 2006
Sleep apnoea expert Dr Rob Pierce is leading the trial, which involves a combination of two drugs - mirtazapine and zonisamide. ... - NEWS.com.au,

Worsening of Borderline Symptoms Under Reboxetine Treatment  Jan 23, 2006
Because of insufficient efficacy and sedation as a side effect the premedication with mirtazapine 30 mg daily was switched to reboxetine, because she refused ... - Journal of Neuropsychiatry (subscription)

Continuity of Antidepressant Treatment for Adults With Depression ...  Jan 24, 2006
...sertraline, paroxetine, fluvoxamine, citalopram, venlafaxine, and venlafaxine extended-release), other newer antidepressants (mirtazapine, bupropion, and ... - Am J Psychiatry (subscription)

Combining Mirtazapine (Remeron) with Other Antidepressants ...  Nov 11, 2005
VANCOUVER, CANADA -- November 11, 2005 -- Depressed patients taking mirtazapine together with fluoxetine (Sarafem) or venlafaxine responded to treatment better ... - DG News

Cypress Bioscience, Inc. to Present at Lazard Capital Markets Life ...  Nov 28, 2005
Specifically, Cypress has licensed mirtazapine related patents from Organon, and patents from two other parties that provide the opportunity to combine ... - Business Wire (press release),

Experts say Prozac might not be the most effective antidepressant  Dec 8, 2005
Results were mixed: Prozac was found less effective than Prothiaden (dothiepin), Zoloft, Remeron (mirtazapine) and Effexor but more effective than the ... - Dominican Today,

Assessing and Treating Sleep Disturbances in Patients With ...  Dec 5, 2005
Trazodone (Desyrel) and mirtazapine (Remeron) can be tried, but no controlled trials have been reported, so safety, efficacy and dosages have not been ... - Psychiatric Times,

In the Name of “Mental Healthâ€?: An Antipsychiatry Perspective ...  Nov 30, 2005
...activist Tooker Gomberg jumped to his death in Halifax in the spring of 2003, a few weeks after being prescribed the antidepressant Remeron (mirtazapine). ... - New Socialist Group,

Antidepressant Detriment and Benefit Assessed at NCDEU  31 Oct 2005
...through increased inhibitory tone. In contrast, mirtazapine (Remeron) and bupropion enhance norepinephrine release. "It should be ... - Psychiatric Times,

Cypress Bioscience Inc. to Present at CE Unterberg, Towbin Life ...  Oct 25, 2005
Specifically, Cypress has licensed mirtazapine related patents from Organon, and patents from two other parties that provide the opportunity to combine ... - Genetic Engineering News,

Easier Treatment for Sleep Apnea  Oct 26, 2005
In their study, every patient taking the antidepressant mirtazapine saw improvement. ... Mirtazapine is only FDA approved for treating depression. ... - KFSN,

Par Pharmaceutical Reports Third-Quarter Sales and Earnings  Oct 27, 2005
...tablets (ODT); * Par announced that its licensing partner, Amide Pharmaceutical, Inc., received final FDA approval and began shipping mirtazapine ODT. ... - PR Newswire (press release),

Rapid dissolving antidepressant enhances compliance in 50 per cent ...  Oct 5, 2005
Remeron RD combines mirtazapine, the active ingredient of Remeron(R) - that acts on both serotonergic and noradrenergic systems - with a rapid dissolving drug ... - Biotech Intelligence (press release),

Fast-Dissolving Antidepressant, Remeron SolTab®, Enhances ...  Oct 9, 2005
Remeron SolTab combines mirtazapine, the active ingredient of Remeron® - that acts on both serotonergic and noradrenergic systems - with a fast dissolving ... - Medical News Today (press release),

Cypress' Stock Plunges After Phase III Miss In Fibromyalgia  Sep 29, 2005
The company entered three licensing agreements for that program: It licensed mirtazapine-related patents from Organon Ltd., of Dublin, Ireland, and patents ... - BioWorld Online (subscription),

Two Pharma Trees Fall  Sep 30, 2005
...along. Its other candidate -- mirtazapine for obstructive sleep apnea -- seems to be a high risk-high-reward sort of prospect. On ... - Motley Fool

Bomb blows away soldier's old life  Oct 9, 2005
He was prescribed medications to help manage his mood, such as Zoloft, amitriptyline and mirtazapine, as well as his pain, such as Imitrex, ibuprofen and ... - Milwaukee Journal Sentinel,

Police Reports:  Oct 11, 2005
During a routine traffic stop, Reit was allegedly found to be in possession of about 2.5 ounces of marijuana, clonazepam and mirtazapine, for which he did not ... - Red Bluff Daily News,

Empiricus: our clinical journal commentator  Oct 4, 2005
Differences between ‘second generation’ antidepressants such as SSRIs, mirtazapine and venlafaxine lie more in their side effect profiles than in their ... - AustralianDoctor.com (subscription),

Police Reports:  11 Oct 2005
During a routine traffic stop, Reit was allegedly found to be in possession of about 2.5 ounces of marijuana, clonazepam and mirtazapine, for which he did not ... - Red Bluff Daily News,

Fast-Dissolving Antidepressant, Remeron SolTab®, Enhances ...  Oct 9, 2005
Remeron SolTab combines mirtazapine, the active ingredient of Remeron® - that acts on both serotonergic and noradrenergic systems - with a fast dissolving ... - Medical News Today (press release),

Cypress Bioscience Inc. to Present at UBS Global Life Sciences ...  Sep 27, 2005
Specifically, Cypress has licensed mirtazapine related patents from Organon, and patents from two other parties that provide the opportunity to combine ... - Business Wire (press release),

Rapid dissolving antidepressant enhances compliance in 50 per cent ...  Oct 5, 2005
Remeron RD combines mirtazapine, the active ingredient of Remeron(R) - that acts on both serotonergic and noradrenergic systems - with a rapid dissolving drug ... - Biotech Intelligence (press release),

Bomb blows away soldier's old life  Oct 9, 2005
He was prescribed medications to help manage his mood, such as Zoloft, amitriptyline and mirtazapine, as well as his pain, such as Imitrex, ibuprofen and ... - Milwaukee Journal Sentinel,

Easier Treatment for Sleep Apnea  Sep 26, 2005
Now neuroscientist David Carley of the University of Illinois, Chicago is trying a new drug treatment, Mirtazapine, a drug that affects serotonin levels in the ... - WFtv.com,

Cypress' Stock Plunges After Phase III Miss In Fibromyalgia  Sep 29, 2005
The company entered three licensing agreements for that program: It licensed mirtazapine-related patents from Organon Ltd., of Dublin, Ireland, and patents ... - BioWorld Online (subscription),

Empiricus: our clinical journal commentator  Oct 4, 2005
Differences between ‘second generation’ antidepressants such as SSRIs, mirtazapine and venlafaxine lie more in their side effect profiles than in their ... - AustralianDoctor.com (subscription),

Second-Generation Antidepressants Equally Effective  Sep 20, 2005
Four non-SSRI second-generation antidepressants were also assessed -- bupropion (Wellbutrin), duloxetine (Cymbalta), mirtazapine (Remeron) and venlafaxine ... - Forbes

Two Pharma Trees Fall  Sep 30, 2005
...along. Its other candidate -- mirtazapine for obstructive sleep apnea -- seems to be a high risk-high-reward sort of prospect. On ... - Motley Fool

Antidepressants, Depression and Suicide  Sep 12, 2005
Cymbalta), venlafaxine (Effexor), escitalopram (Lexapro), fluvoxamine (Luvox), paroxetine (Paxil), fluoxetine (Prozac), mirtazapine (Remeron), nefazodone ... - Bella Online

Bilateral Exophthalmos and Depression: Not Always Endocrine ...  Sep 24, 2005
His condition was initially therapy-resistant because a series of antidepressant (eg, paroxetine, venlafaxine, citalopram, nefazodone, mirtazapine and finally ... - Journal of Neuropsychiatry (subscription)

Many meds don't mix with the sun  Sep 21, 2005
...escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), imipramine (To-franil), maprotiline (Ludiomil), mirtazapine (Remeron), nefazo-done ... - Pioneer Press,

Furosemide may increase the ototoxic potential of aminoglycoside antibiotics, especially in the presence of impaired renal function. Except in life-threatening situations, avoid this combination.

Furosemide should not be used concomitantly with ethacrynic acid because of the possibility of ototoxicity. Patients receiving high doses of salicylates concomitantly with furosemide, as in rheumatic disease, may experience salicylate toxicity at lower doses because of competitive renal excretory sites.

Furosemide has a tendency to antagonize the skeletal muscle relaxing effect of tubocurarine and may potentiate the action of succinylcholine.

Lithium generally should not be given with diuretics because they reduce lithium's renal clearance and add a high risk of lithium toxicity.

Furosemide may add to or potentiate the therapeutic effect of other antihypertensive drugs. Potentiation occurs with ganglionic or peripheral adrenergic blocking drugs.

Furosemide may decrease arterial responsiveness to norepinephrine. However, norepinephrine may still be used effectively.

Tablets

Simultaneous administration of sucralfate and furosemide tablets may reduce the natriuretic and antihypertensive effects of furosemide. Patients receiving both drugs should be observed closely to determine if the desired diuretic and/or antihypertensive effect of furosemide is achieved. The intake of furosemide and sucralfate should be separated by at least two hours.

Tablets, Injection, and Oral Solution

One study in six subjects demonstrated that the combination of furosemide and acetylsalicylic acid temporarily reduced creatinine clearance in patients with chronic renal insufficiency. There are case reports of patients who developed increased BUN, serum creatinine and serum potassium levels, and weight gain when furosemide was used in conjunction with NSAIDs.

Literature reports indicate that coadministration of indomethacin may reduce the natriuretic and antihypertensive effects of furosemide in some patients by inhibiting prostaglandin synthesis. Indomethacin may also affect plasma renin levels, aldosterone excretion, and renin profile evaluation. Patients receiving both indomethacin and furosemide should be observed closely to determine if the desired diuretic and/or antihypertensive effect of furosemide is achieved.