Frova: profile and news

Endo Pharmaceuticals Reports Fourth Quarter and Full-Year 2005 ...  Feb 15, 2006
Frova(R). Net sales of Frova(R) were $13.0 million for the three months ended December 31, 2005 compared with $6.4 million in the same period in 2004. ... - MSN Money

Pa. drugmaker aggressively diversifies  Feb 7, 2006
The company also expects to file a supplemental application for Frova, a drug to treat acute migraine headaches it licenses from Vernalis Plc. ... - The News Journal,

Endo reports strong quarter, year results  Feb 16, 2006
...lower court. Sales of Frova, used to treat migraine sufferers, reached $38.1 million in 2005, versus $11.4 million in 2004. Endo ... - Chester Daily Local Online,

Updates, advisories and surprises  Feb 15, 2006
...more than doubled to $72.9 million, or 54 cents a share, with revenue climbing 53% to $241 million on sales of drugs including Lidoderm, Percocet and Frova. ... - Investor's Business Daily (subscription)

Pa. drugmaker aggressively diversifies  Feb 7, 2006
The company also expects to file a supplemental application for Frova, a drug to treat acute migraine headaches it licenses from Vernalis Plc. ... - The News Journal,

Vernalis PLC Launch of US Sales Force  Jan 24, 2006
This 34 strong team is marketing Vernalis' Parkinson's disease drug Apokyn(R), as well as co-marketing the company's migraine drug, Frova(R), alongside Endo ... - PharmaLive.com (press release),

Vernalis starts selling Parkinson's drug Apokyn in US  Jan 24, 2006
PLC said its 34-strong specialty neurology US sales force has started to market its Parkinson's disease drug Apokyn and migraine drug Frova, alongside Endo ... - Forbes

Elan meldt financiële resultaten vierde kwartaal en hele jaar ...  Jan 31, 2006
...manufacturing business in Italy, the pain portfolio of products, Actiq(TM), the dermatology portfolio of products, Abelcet(TM) US and Canada, Frova(TM), Myobloc ... - Netherlands Corporate News (persbericht),

Coping With Migraine Headaches  Nov 10, 2005
...or injections. One comes in all three. Among these are: Imitrex, Replpax, Frova, Zomig, Maxalt, Amerg, and Axert. These drugs actually ... - 7Online.com,

Could Your Sinus Headache Actually Be a Migraine?  Nov 17, 2005
...tablet, spray or injections form. They include Imitrex, Replpax, Frova, Zomig, Maxalt, Amerg and Axert. Researchers are still fine ... - ABC News

Elan and UCB Announce Agreement to co-promote New Migraine Drug ...  Oct 3, 2005
...and chemical group ("UCB"), announced today that they have entered into an agreement to co-promote the new migraine drug FROVA (frovatriptan succinate) in the ... - Biotechnology Investment Today (Press Release),

Ferghana and Gargoyle Merge to Create Leading Specialist ...  Oct 10, 2005
...recently concluded are: sole manager of Series B $42.5M financing for Zelos Therapeutics, advisor to Vernalis plc on its $400M+ partnering of Frova(TM) with ... - Yahoo! News (press release)

Simi Rotarians not afraid to raise funds by raising eyebrows  Jul 31, 2005
Barbara Frova has pulled on sneakers for any number of charity walks. The Simi Valley business owner has slipped into gowns for ... - Ventura County Star (subscription)

Endo profit up 56% in quarter  Jul 22, 2005
..."With the growth we expect from Lidoderm, combined with the ongoing launches of Frova and DepoDur" to treat pain, "and the depth of our development pipeline ... - Philadelphia Inquirer

Endo Pharmaceuticals Reports 2005 Second Quarter Financial Results  Jul 21, 2005
With the projected growth of Lidoderm®, the ongoing launches of Frova® and DepoDur(TM), and the continued progress of our substantial development pipeline ... - Yahoo News (press release) <**results**>

Vernalis gets Frova trial boost  Jun 27, 2005
In a final stage study ahead of submission to the US regulators, Vernalis said that Frova was well-tolerated when used as a six-day dosing regimen for up to ... - ShareCast

Vernalis Reports Frovatriptan Interim Phase III Safety Data  Jun 27, 2005
...announced six-month interim safety data for frovatriptan, in development for the prevention of menstrually related migraine (MRM) and marketed as Frova(R) in ... - PharmaLive.com (press release)

TechMARK movers: Vernalis climbs, Medisys slides  Jun 27, 2005
In a final stage study ahead of submission to the US regulators, Vernalis said that Frova was well tolerated when used as a six-day dosing regimen for up to ... - ShareCast

Department of Anesthesiology; Sanjay Gandhi Post Graduate ...  Jun 23, 2005
...used percutaneous dilational tracheostomy kits are Ciaglia’s serial dilators, Griggs guidewire dilating forceps, Ciaglia Blue Rhino, and Frova’s PercTwist ... - Anesthesia & Analgesia (subscription)

London open: Oil concerns outweigh PartyGaming surge  Jun 27, 2005
...particular rising strongly. Vernalis rose as its Frova anti-migraine treatment came through another stage of its approval process. - ShareCast

London midmorning: Oil fears haunt Footsie  Jun 27, 2005
...six months. Vernalis rose as its Frova anti-migraine treatment came through another stage of its approval process. Caravan park ... - ShareCast

London afternoon: US could lift Footsie  Jun 27, 2005
...recent trade has been erratic. Vernalis rose as its Frova anti-migraine treatment came through another stage of its approval process. - ShareCast,

Vernalis gets Frova trial boost  13 Sep 2002
In a final stage study ahead of submission to the US regulators, Vernalis said that Frova was well-tolerated when used as a six-day dosing regimen for up to ... - ShareCast,

London midday: Scant support for Footsie  13 Sep 2002
...recent trade has been erratic. Vernalis rose as its Frova anti-migraine treatment came through another stage of its approval process. - ShareCast,

Elan Corporation PLC UK Regulatory Announcement: 1st Quarter ...  Apr 27, 2005
...manufacturing business in Italy, the pain portfolio of products, Actiq(TM), the dermatology portfolio of products, Abelcet(TM) US and Canada, Frova(TM), Myobloc ... - Business Wire,

Menstrual migraines cause pain, cost billions  Apr 26, 2005
Frovatriptan, or Frova, a member of the class of drugs called triptans, is one treatment for menstrual migraines – successfully in the case of Williams, she ... - The Spokesman Review (subscription)

Endo Pharmaceuticals Reports First Quarter Financial Results  Apr 21, 2005
With the ongoing launches of Frova® and DepoDur(TM), the strong prescription demand for Lidoderm®, the addition in the first quarter to our pipeline of the ... - Yahoo News

Elan Corporation PLC UK Regulatory Announcement: 1st Quarter ...  Apr 27, 2005
...manufacturing business in Italy, the pain portfolio of products, Actiq(TM), the dermatology portfolio of products, Abelcet(TM) US and Canada, Frova(TM), Myobloc ... - Business Wire

Sports folks are getting too personal  Apr 18, 2005
...last week. Williams is the new spokesperson for Frova, a medicine she takes to help her cope with menstrual migraines. Remember ... - San Jose Mercury News

Serena Williams Launches 'RALLY for Menstrual Migraine' Campaign ...  Apr 12, 2005
...to tell women my story, let them know that there is hope and that they should seek help." Last year, the 23-year-old Williams began using Frova(R) (frovatriptan ... - PR Newswire

Serena Williams Launches 'RALLY for Menstrual Migraine' Campaign ...  Apr 12, 2005
Last year, the 23-year-old Williams began using Frova(R) (frovatriptan), Endo's migraine medication, to successfully treat her menstrual migraines, which had ... - PharmaLive.com

Area company lures big-name endorser  Apr 13, 2005
...help.". Williams said Frova, marketed by Endo Pharmaceuticals, cured her of menstrual migraines after other treatments failed. Endo ... - The News Journal

Serena Williams doubles with Endo  Apr 12, 2005
Last year, the 23-year-old Williams began using Frova, Endo's migraine medication, to successfully treat her menstrual migraines. ... - Philadelphia Business Journal

I feel like Tiger, says Serena  Apr 13, 2005
...interests in acting and fashion design, writing an advice book for teenagers with her sister, Venus, and promoting a migraine headache remedy, Frova, she said ... - Independent Online

Serena pushes headache relief  Apr 18, 2005
..."It was the last straw," she said. "I lost to this girl I would never lose to because I had such an incredible headache.". she try the medication Frova. ... - Afternoon Dispatch & Courier

Fired-up fans have too short of a fuse  Apr 13, 2005
...doctor. I found this medication Frova, which has been able to help me a lot. I don't have to deal with the migraines anymore. I ... - Chicago Sun-Times

Serena Pushes Headache Relief  Apr 11, 2005
..."I lost to this girl I would never lose to because I had such an incredible headache.". A doctor then recommended she try the medication Frova. ... - Chicago Tribune (subscription)

Vernalis Exercises Option to Co-Promote Frova with Endo ...  Feb 24, 2005
Vernalis licensed exclusive North American sales and marketing rights to frovatriptan (marketed as Frova(R) in the US) to Endo in July 2004. ... - PharmaLive.com (press release),

Vernalis to raise £30m in new offer  Feb 24, 2005
It will use the cash to set up an American subsidiary to promote its migraine treatment, Frova, with its partner, Endo Pharmaceuticals. ... - Guardian,

London Markets Earnings help steady London  Feb 24, 2005
...option to have Endo Pharmaceuticals (ENDP: news, chart, profile) fund and assist the development of a North American sales team under its Frova drug marketing ... - MarketWatch

Ergot-containing drugs have been reported to cause prolonged vasospastic reactions. Due to a theoretical risk of a pharmacodynamic interaction, use of ergotamine-containing or ergot-type medications (like dihydroergotamine or methysergide) and FROVA within 24 hours of each other should be avoided (see CONTRAINDICATIONS).

Concomitant use of other 5-HT_1B/1D agonists within 24 hours of FROVA treatment is not recommended.

Selective serotonin reuptake inhibitors (SSRIs) (e.g., fluoxetine, fluvoxamine, paroxetine, sertraline) have been reported, rarely, to cause weakness, hyperreflexia, and incoordination when coadministered with 5-HT₁ agonists. If concomitant treatment with frovatriptan and an SSRI is clinically warranted, appropriate observation of the patient is advised.

Drug/Laboratory Test Interactions

FROVA is not known to interfere with commonly employed clinical laboratory tests.